Synthesis and Central Nervous System Actions of Thyrotropin-Releasing Hormone Analogues Containing a Dihydroorotic Acid Moiety

Journal of Medicinal Chemistry

Volumn 33, Issue 8, 1990, Pages 2130-2137

  Suzuki, Mamoru ^a   Sugano, Hiroshi ^a   Matsumoto, Kazuo ^a   Yamamura, Michio ^a   Ishida, Ryuichi ^a  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

(1 METHYL 4,5 DIHYDROOROTYL)HISTIDYLPROLINAMIDE; OROTIRELIN; PROTIRELIN; PROTIRELIN DERIVATIVE; PYRO 2 AMINOADIPYLHISTIDYLTHIAZOLIDINE 4 CARBOXAMIDE; TALTIRELIN; THYROTROPIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DRUG SCREENING; DRUG SYNTHESIS; HYPOTHERMIA; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MOTOR ACTIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION;

ANESTHESIA; CENTRAL NERVOUS SYSTEM; CHEMISTRY; HYPOTHERMIA; MOLECULAR STRUCTURE; MOTOR ACTIVITY; OROTIC ACID; PENTOBARBITAL; RESERPINE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; THYROTROPIN; THYROTROPIN-RELEASING HORMONE;

EID: 0025280640     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00170a014     Document Type: Article

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