Phosphatidic acid and not diacylglycerol generated by phospholipase D is functionally linked to the activation of the NADPH oxidase by FMLP in human neutrophils

Biochemical and Biophysical Research Communications

Volumn 168, Issue 1, 1990, Pages 320-327

  Rossi, Filippo ^a   Grzeskowiak, Miroslawa ^a   Bianca, Vittorina Della ^a   Calzetti, Federica ^a   Gandini, Giorgio ^b  

^a UNIVERSITY OF VERONA   (Italy)

^b UNIVERSITY AND HOSPITAL TRUST OF VERONA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DIACYLGLYCEROL; PHOSPHATIDIC ACID; PHOSPHOLIPID; PROTEIN KINASE C; RADIOISOTOPE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ARTICLE; HUMAN; HUMAN CELL; NEUTROPHIL; PRIORITY JOURNAL;

BUTANOLS; CYTOCHALASIN B; DIGLYCERIDES; ENZYME ACTIVATION; GLYCERIDES; HUMAN; IN VITRO; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NADH, NADPH OXIDOREDUCTASES; NADPH OXIDASE; NEUTROPHILS; OXYGEN CONSUMPTION; PHOSPHATIDIC ACIDS; PHOSPHOLIPASE D; PHOSPHOLIPASES; PROPRANOLOL; SUPPORT, NON-U.S. GOV'T;

EID: 0025274039     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/0006-291X(90)91711-Z     Document Type: Article

References (23)

1. Polyphosphoinositide phosphodiesterase: regulation by a novel guanine nucleotide binding protein, Gp
2. Calcium influx stimulates a second pathway for sustained diacylglycerol production in leukocytes activated by chemoattractants.
3. Modulation of rat brain cytosolic phosphatidate phosphohydrolase: Effect of cationic amphiphilic drugs and divalent cations