Arcaine is a competitive antagonist of the polyamine site on the NMDA receptor

European Journal of Pharmacology

Volumn 177, Issue 3, 1990, Pages 215-216

  Reynolds, Ian J ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGMATINE; ARCAINE; DIZOCILPINE; GLUTAMIC ACID; GLYCINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; RADIOISOTOPE; SPERMIDINE;

ANIMAL CELL; ARTICLE; DRUG BINDING; DRUG CONCENTRATION; NONHUMAN; PRIORITY JOURNAL;

BIGUANIDES; BINDING, COMPETITIVE; BIOGENIC POLYAMINES; DIBENZOCYCLOHEPTENES; DIZOCILPINE MALEATE; RECEPTORS, N-METHYL-D-ASPARTATE; RECEPTORS, NEUROTRANSMITTER; SPERMIDINE; SUPPORT, NON-U.S. GOV'T;

EID: 0025273293     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(90)90274-A     Document Type: Article

References (5)

1. Ifenprodil and SL 820715 are antagonists at the polyamine site of the N-methyl-D-aspartate receptor
2. Excitatory amino acid receptors in the vertebrate central nervous system
3. 3H]MK-801 binding to the N-methyl-D-aspartate receptor-ion channel complex by L-glutamate, glycine and polyamines
4. Ifenprodil is a novel type of NMDA receptor antagonist: interaction with polyamines
5. 3H-labelled MK-801 binding to the excitatory amino acid receptor complex from rat brain is enhanced by glycine