α‐Helical coiled coils and bundles: How to design an α‐helical protein

Proteins: Structure, Function, and Bioinformatics

Volumn 7, Issue 1, 1990, Pages 1-15

  Cohen, Carolyn ^a   Parry, David A D ^b  

^a BRANDEIS UNIVERSITY   (United States)

^b MASSEY UNIVERSITY   (New Zealand)

Author keywords

4 helix bundle; membrane spanning proteins; fibrous proteins

Indexed keywords

ALPHA HELIX; PRIORITY JOURNAL; PROTEIN STRUCTURE; REVIEW;

AMINO ACID SEQUENCE; ANIMAL; BLOOD PROTEINS; INTERMEDIATE FILAMENTS; MEMBRANE PROTEINS; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEINS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0025272940     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.340070102     Document Type: Review

References (108)

1. Last blackboard
2. Croonian Lecture On the structure of biological fibers and the problem of muscle
3. The structure of proteins: Two hydrogen‐bonded helical configurations of the polypeptide chain
4. Helix signals in proteins
5. Amino acid preferences for specific locations at the ends of α helices
6. The structure of feather keratin
7. The packing of α‐helices: Simple coiled coils
8. α‐helical coiled coils—A wide spread motif in proteins
9. Tropomyosin coiled‐coil in teractions: Evidence for an unstaggered structure
10. Engineering aspects of protein structure
11. General architecture of the α‐helical globule
12. Tropomyosin crystal structure and muscle regulation
13. Analysis of the primary structure of α‐tropomyosin
14. Crystalline tubes of myosin subfragment‐2 showing the coiled‐coil and molecular interaction geometry
15. Compound helical configurations of polypeptide chains: Structure of proteins of the α‐keratin type
16. Intrachain potential energy of the α‐helix and of the coiled‐coil strand
17. Coiled‐coils in α‐helix‐containing proteins: Analysis of the residue types within the heptad repeat and the use of these data in the predictin of coiled‐coils in other proteins
18. Intermediate filament structure:3. Analysis of sequence homologies
19. Intermediate filament structure. 1. Analysis of IF protein sequence data
20. Designation of sequences involved in the “coiled‐coil” interdomainal connections in fibrinogen: Construction of an atomic scale model
21. Fibrinogen: A preliminary analysis of the amino acid sequences of the portions of the α, β and γ chains postulated to form the interdomainal link between globular regions of the molecule
22. Molecular substructure of a viral receptor‐receptor‐recognition protein. The gp17 tail‐fiber of bacteriophage T7
23. A four‐strand coiled‐coil model for some insect fibrous proteins
24. Amino Acid sequence and structural repeats in schistosome paramyosin match those of myosin
25. The paramyosin gene (unc‐15) of Caenorhabditis elegans: Molecular cloning, nucleotide sequence and models for thick filament assembly
26. Sequence analysis of the complete Caenorhabditis elegans myosin heavy chain gene family
27. Homologies in both primary and secondary structural between nuclear envelope and intermediate filament proteins
28. Structural studies on lamin: Similarities and difference between lamin and intermediate filament proteins
29. Conformation characteristics of the complete sequence of group A streptococcal M6 protein
30. Isolation of dynein heavy chain cDNAs from trout testis which predict an extensive carboxyl‐terminal α‐helical coiled‐coil domain
31. Protein design using model synthetic peptides
32. Protein design, a minimalist approach
33. The role of the α‐helix dipole in protein function and structure
34. Stabilization of the long central helix of troponin C by intrahelical salt bridges between charged amino acid side chains
35. + salt bridges in short peptides of de novo design
36. Dipoles of the α‐helix and β‐sheet: Their role in protein folding
37. Tests of the helix dpole model for stabilization of α‐helices
38. Energetics of the structure of the four‐α‐helix bundle in proteins
39. Principles that determine the structure of proteins
40. Structural and patterns in globular proteins
41. Structural and functional diversity in 4‐α‐helical proteins
42. Prediction of the secondary and tertiary structures of interferon from four homologous amino acid sequences
43. M. Synthesis, antiviral activity and conformational characterization of mouse‐human α‐interferon hybrids
44. Conformational homologies among cytokines: Interleukins and colony stimulating factors
45. Helix geometry in proteins
46. Topological distribution of four‐α‐helix bundles
47. Three‐dimensional structure of a genetically engineered variant of porcine growth hormone
48. The spatial structural of horse spleen apoferritin
49. Principles and patterns of protein conformation
50. Structure of the ColE1 Rop protein at 1.7 Å resolution
51. Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution
52. 6 Å‐resolution X‐ray structure of a variable surface glycoprotein from Trypanosoma brucei
53. α‐helical coiled‐coil structures of Trypanosoma brucei
54. Two variant surface glycoprotein of Trypanosoma Brucei of different sequence classes have similar 6 A resolution X‐ray structures
55. Erythrocyte spectrin is comprised of many homologous triple helical segments
56. α‐actinins and the DMD protein contain spectrin‐like repeats
57. Stereochemical consideration for constructing α‐helical protein bundles with particular application to membrane protein
58. The DNA binding domain of the rat liver nuclear protein C/EBP is bipartite
59. Evidence that the leucine zipper is a coiled coil
60. Leucine zipper motif extends
61. Disulphide bridges in globular proteins
62. The anatomy and taxonomy of protein structure
63. Disulphide bonding in‐α‐keratin
64. Ion pairs in alpha helices
65. Stereochemistry of salt‐bridge formation in α‐helices and β‐strands
66. The design, synthesis and crystallization of an alpha‐helical peptide
67. Design, expression, and preliminary characterization of felix: A model protein
68. Three‐dimensional structure of membrane and surface proteins
69. Identifying nonpolar transbilayer helices in amino acid sequences of membrane proteins
70. Three‐dimensional model of purple membrane obtained by electron microscopy
71. Images of purple membrane at 2.8 Å resolution obtained by cryo‐electron microscopy
72. Structure of the protein subunits in the photosynthetic reaction centre of Rhodopseudomonas viridis, at 3Å resolution
73. Structure of the reaction center from Rhodobacter sphaeroids R‐26:The protein subunits
74. Structure of the reaction center from Rhodobactersphaeroides R‐26:The cofactors
75. Multi‐spanning membrane proteins: How accurate are the models?
76. On the folding and insertion of globular membrane proteins
77. A simple method for displaying the hydropathic character of a protein
78. Folding patterns of porin and bacteriorhodopsin
79. Evaluation of methods for the prediction of membrane protein secondary structures
80. Amphipathic analysis and possible formation of the ion channel in an acetlycholine receptor
81. The structure of the lactose permease derived from Raman spectroscopy and prediction methods
82. Structure of the reaction center from Rhodobacter sphaeroides R‐26 and 2.4:2 Symmetry relations and sequence comparisons between different species
83. The bacterial photosynthetic reaction center as a model for membrane protein
84. Structure of the reaction center from Rhodobacter sphaeroides R‐26: Membrane‐protein interactions
85. Bacteriorhodopsin is an inside‐out protein
86. Membrane transport through α‐helical bundles. IV. Preliminary model building investigation of helix‐helix interactions
87. Topology of the 32‐kd liver gap junction protein determined by site‐directed antibody localizations
88. Hydrophobic organization of membrane proteins
89. Structure of the membrane‐pore‐forming fragment of conlicin A
90. Secondary structure of the pore‐forming coliclin a and its C‐terminal fragment. Experimental fact and structure prediction
91. Is there a common design for cell membrane channels?
92. Quaternary structure of the acetylcholine receptor,
93. On channel of acetylcholine receptor reconstructed from images of postsynaptic membranes
94. Molecular model of the action potential sodium channel
95. Sequence of a probable potassium channel component encoded at Shaker locus of Drosophila
96. Structure of the junction between communicating cells
97. A voltage‐gated ion channel model inferred from the crystal structure of alamethicin at 1.5‐Å resolution
98. Lactose permease: A carrier on the move
99. Primary structure and transmembrane orientation of the murine anion exchange protein
100. Synthetic amphiphilic peptide models for protein ion channels
101. Some design principles for structurally stable proteins
102. Structure of ferricytochrome c' from Rhodospirillum molischianum at 1.67 Å resolution
103. Path of the polypeptide in bacteriorhodopsin