Long‐term maintenance of the adult pattern of liver‐specific expression for P‐450b, P‐450e, albumin and α‐fetoprotein genes in intrasplenically transplanted hepatocytes

Hepatology

Volumn 11, Issue 4, 1990, Pages 585-592

  Maganto, Paloma ^a   Traber, Peter G ^a   Rusnell, Christopher ^a   Dobbins Iii, William O ^a   Keren, David ^b   Gumucio, Jorge J ^a  

^a Section of Gastroenterology   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; ALPHA FETOPROTEIN;

ANIMAL CELL; ARTICLE; CELL CULTURE; GENE EXPRESSION; HISTOCHEMISTRY; HISTOLOGY; HUMAN CELL; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; SPLEEN; TISSUE TRANSPLANTATION;

ALBUMINS; ALPHA-FETOPROTEINS; ANIMAL; BLOTTING, NORTHERN; CYTOCHROME P-450 ENZYME SYSTEM; GENE EXPRESSION; GENE EXPRESSION REGULATION; LIVER; LIVER TRANSPLANTATION; MALE; PHENOBARBITAL; RATS; RATS, INBRED F344; RNA, MESSENGER; SPLEEN; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; TIME FACTORS; TRANSPLANTATION, HETEROTOPIC;

EID: 0025268528     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.1840110410     Document Type: Article

References (27)

1. Hepatocellular transplantation for treatment of d‐galactosamine‐induced acute liver failure in rats
2. Hepatocyte transplantation for enzyme deficiency disease in congenic rats
3. Observations on the fine structure of long‐survived isolated hepatocytes inoculated into rat spleen
4. Transplanted cryopreserved hepatocytes: an approach for future support in liver failure
5. Primary structure of a cytochrome P‐450: coding nucleotide sequence of phenobarbital‐inducible cytochrome P‐450 cDNA from rat liver
6. A cytochrome P‐450 multigene family: characterization of a gene activated by phenobarbital administration
7. Cloned cytochrome P‐450 cDNA
8. Gene structure of a major form of phenobarbital‐inducible cytochrome P‐450 in rat liver
9. The microcirculatory hepatic unit
10. Zonal signal heterogeneity and induction of hepatocyte heterogeneity.
11. Sublobular compartmentation of pharmacological events (SCOPE): metabolic fluxes in periportal and pericentral regions of the liver lobule
12. Physiological significance and regulation of hepatocellular heterogeneity
13. Cryopreservation and transplantation of hepatocytes: an approach for culture and clinical application
14. Isolation of biologically active ribonucleic acid from sources rich in ribonuclease
15. Phenobarbital induction of rat liver cytochromes P450b and P450e: quantitation of specific RNAs by hybridization to synthetic oligodeoxyribonucleotide probes
16. Expression of cytochrome P450b and P450e genes in small intestinal mucosa of rats following treatment with phenobarbital, polyhalogenated biphenyls, and organochlorine pesticides
17. Technique for radiolabelling DNA restriction endonuclease fragments to high specific activity
18. Transcriptional control of the murine albumin/alpha fetoprotein locus during development
19. Alpha and luteinizing hormone beta messenger ribonucleic acid of male and female rats after castration: quantitation using an optimized RNA dot blot hybridization assay
20. Cytochrome P450 of small intestinal epithelial cells. Immunochemical characterization of increase in cytochrome P450 caused by phenobarbital
21. Diagnostic pathology of the intestine and colon
22. Dependence of liverspecific transcription on tissue organization
23. Regulation of gene expression in adult rat hepatocytes cultured on a basement membrane matrix
24. Transcriptional regulation of rat liver epoxide hydratase, NADPH‐cytochrome P‐450 oxidoreductase, and cytochrome P‐450b genes by phenobarbital
25. Intrahepatic bile duct development in the rat: a cytokeratin‐immunohistochemical study
26. Demonstration by in situ hybridization of the zonal modulation of rat liver cytochrome P450b and P450e gene expression after phenobarbital
27. Intrahepatic distribution of xenobiotic‐metabolizing enzymes.