Antidepressant-like effects of trazodone on a behavioral screen are mediated by trazodone, not the metabolite m-chlorophenylpiperazine

European Journal of Pharmacology

Volumn 177, Issue 3, 1990, Pages 137-144

  Li, Abby A ^a   Marek, Gerard J ^a   Hand, Timothy H ^a   Seiden, Lewis S ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

5 Hydroxytryptamine (5 HT, serotonin); Antidepressants (atypical); DRL 72 s schedule; m CPP (m chlorophenylpiperazine); Trazodone

Indexed keywords

(3 CHLOROPHENYL)PIPERAZINE; DRUG METABOLITE; PROADIFEN; TRAZODONE;

ANIMAL EXPERIMENT; ARTICLE; DEPRESSION; INSTRUMENTAL CONDITIONING; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; PSYCHOLOGICAL ASPECT; RAT; REINFORCEMENT;

ANIMAL; ANTIDEPRESSIVE AGENTS; BEHAVIOR, ANIMAL; CONDITIONING, OPERANT; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; PIPERAZINES; PROADIFEN; RATS; RATS, INBRED STRAINS; REINFORCEMENT SCHEDULE; SUPPORT, U.S. GOV'T, P.H.S.; TRAZODONE;

EID: 0025265617     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(90)90263-6     Document Type: Article

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