Tachykinin receptors in the circular muscle of the guinea-pig ileum

British Journal of Pharmacology

Volumn 101, Issue 4, 1990, Pages 996-1000

  Maggi, C A ^a   Patacchini, R ^a   Giachetti, A ^a   Meli, A ^a  

^a Menarini Ricerche SpA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ATROPINE; BESTATIN; CAPTOPRIL; CARBACHOL; NEUROKININ A; NEUROKININ DERIVATIVE; RECEPTOR SUBTYPE; SUBSTANCE P; TACHYKININ RECEPTOR; TETRODOTOXIN; THIORPHAN;

ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; ELECTROSTIMULATION; GUINEA PIG; ILEUM; MALE; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE CONTRACTILITY;

EID: 0025258437     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1990.tb14195.x     Document Type: Article

References (32)

1. BARTHO', L. & HOLZER, P. (1985). Search for a physiological role of substance P in gastrointestinal motility. Neuroscience, 16, 1–32.
2. BARTHO', L., HOLZER, P., LEANDER, S. & LEMBECK, F. (1989). Evidence for an involvement of substance P but not cholecystokinin‐like peptides in hexamethonium‐resistant intestinal peristalsis. Neuroscience, 28, 211–217.
3. BAUER, V. & KURIYAMA, H. (1982). The nature of non‐cholinergic non‐adrenergic transmission in longitudinal and circular muscles of the guinea‐pig ileum. J. Physiol., 332, 375–391.
4. BURCHER, E., BUCK, S.H., LOVENBERG, W. & O'DONOHUE, T.L. (1986). Characterization and autoradiographic localization of multiple tachykinin binding sites in gastrointestinal tract and bladder. J. Pharmacol. Exp. Ther., 236, 819–831.
5. COSTA, M., FURNESS, J.B., LLEWELLYN‐SMITH, D. & CUELLO A.C. (1981). Projections of substance P‐containing neurons within the guinea‐pig small intestine, Neuroscience, 6, 411–424.
6. COSTA, M., FURNESS, J.B., PULLIN, C.O. & BORNSTEIN, J. (1985). Substance P enteric neurons mediate non‐cholinergic transmission to the circular muscle of the guinea‐pig intestine. Naunyn Schmiedebergs Arch. Pharmacol., 328, 446–453.
7. DEVILLIER, P., ADVENIER, C., DRAPEAU, G., MARSAC, J. & REGOLI, D. (1988). Comparison of the effect of epithelium removal and of an enkephalinase inhibitor on the neurokinin‐induced contractions of guinea‐pig isolated trachea, Br. J. Pharmacol., 94, 675–684.
8. DION, S., D'ORLEANS‐JUSTE, P., DRAPEAU, G., RHALEB, N.E., ROUISSI, N., TOUSIGNANT, C. & REGOLI, D. (1987). Characterization of neurokinin receptors in various isolated organs by the use of selective agonists. Life Sci., 41, 2269–2278.
9. DONNERER, F., HOLZER, P. & LEMBECK, F. (1984). Release of dynorphin, somatostatin and substance P from the vascularly perfused small intestine of the guinea‐pig during peristalsis. Br. J. Pharmacol., 83, 919–925.
10. DRAPEAU, G., D'ORLEANS‐JUSTE, P., DION, S., RHALEB, N.E., ROUISSI, N.E. & REGOLI, D. (1987). Selective agonists for substance P and neurokinin receptors, Neuropeptides, 10, 43–54.
11. FOX, J.E.T. & DANIEL, E.E. (1986). Substance P: a potential inhibitor of the canine small intestine in vivo. Am. J. Physiol., 250, G21–G27.
12. FOX, J.E.T., McDONALD, T.J. ALFORD, L. & DANIEL, E.E. (1986). Tachykinin activation of muscarinic inhibition in canine small intestine is SP‐P in nature. Life Sci., 39, 1123–1128.
13. FRANCO, R., COSTA, M. & FURNESS, J.B. (1979). Evidence for the release of endogenous substance P from intestinal nerves. Naunyn Schmiedebergs Arch. Pharmacol., 306, 195–201.
14. GUARD, S. & WATSON, S.P. (1987). Evidence for neurokinin‐3 receptor‐mediated tachykinin release in the guinea‐pig ileum, Eur. J. Pharmacol., 144, 409–412.
15. HOLZER, P. (1989). Ascending enteric reflex: multiple neurotransmitter systems and interactions, Am. J. Physiol., 256, G540–G545.
16. HOLZER, P., LEMBECK, F. & DONNERER, J. (1980). Caerulein, substance P, serotonin and cholinomimetics induce rhythmic contractions of the intestinal circular muscle, Naunyn Schmiedebergs Arch. Pharmacol., 312, 131–137.
17. JACOBY, H.I., LOPEZ, I., WRIGHT, D. & VAUGHT, J.L. (1986). Differentiation of multiple neurokinin receptors in the guinea‐pig ileum, Life Sci., 39, 1995–2003.
18. KILBINGER, H., STAUB, P., ERLHOF, I. & HOLZER, P. (1986). Antagonist discrimination between subtypes of tachykinin receptors in the guinea‐pig ileum, Naunyn Schmiedebergs Arch. Pharmacol., 334, 181–187.
19. LAUFER, R., GILON, C., CHOREV, M. & SELINGER, Z. (1986). Characterization of neurokinin B receptor site in rat brain using a highly selective radioligand. J. Biol. Chem., 261, 10257–10263.
20. LAUFER, R., GILON, C., CHOREV, M. & SELINGER, Z. (1988). Desensitization with selective agonists discriminates between multiple tachykinin receptors. J. Pharmacol. Exp. Ther., 245, 639–643.
21. LEE, C.M., IVERSEN, L.L., HANLEY, M.R. & SANDBERG, B.E.B. (1982). The possible existence of multiple receptors for substance P. Naunyn Schmiedebergs Arch. Pharmacol., 318, 281–288.
22. LLEWELLYN‐SMITH, I.J., FURNESS, J.B., GIBBINS, I.L. & COSTA, M. (1988). Quantitative ultrastructural analysis of enkephalin‐, substance P‐ and VIP‐immunoreactive nerve fibers in the circular muscle of the guinea‐pig small intestine. J. Comp. Neurol., 272, 139–148.
23. LLEWELLYN‐SMITH, I.J., FURNESS, J.B. & COSTA, A. (1989). Ultrastructural analysis of substance P‐immunoreactive nerve fibers in myenteric ganglia of guinea‐pig small intestine. J. Neuroscience, 9, 167–174.
24. MAGGI, C.A., PATACCHINI, R., GIULIANI, S., ROVERO, P., DION, S., REGOLI, D., GIACHETTI, A. & MELI, A. (1990b). Competitive antagonists discriminate between NK‐2 tachykinin receptor subtypes. Br. J. Pharmacol. 100, 588–592.
25. MAGGI, C.A., PATACCHINI, R., SANTICIOLI, P., GIULIANI, S., TURINI, D., BARBANTI, G., BENEFORTI, P., MISURI, D. & MELI, A. (1989). Human isolated small intestine: motor responses of the longitudinal muscle to field stimulation and exogenous neuropeptides. Naunyn Schmiedebergs Arch. Pharmacol., 339, 415–423.
26. MAGGI, C.A., PATACCHINI, R., SANTICIOLI, P., GIULIANI, S., TURINI, D., BARBANTI, G., GIACHETTI, A. & MELI, A. (1990a). Human isolated ileum: motor responses of the circular muscle to electrical field stimulation and exogenous neuropeptides Naunyn Schmiedebergs Arch. Pharmacol., 341, 256–261.
27. PATACCHINI, R., MAGGI, C.A., ROVERO, P., DRAPEAU, G., REGOLI, D. & MELI, A. (1989). Effect of thiorphan on tachykinin‐induced potentiation of nerve‐mediated contractions of the rat isolated vas deferens, J. Pharmacol. Exp. Ther., 250, 678–681.
28. ROVERO, P., RHALEB, N.E., DION, S., ROUISSI, N., TOUSIGNANT, C., TELEMAQUE, S., DRAPEAU, G. & REGOLI, D. (1989). Structure activity studies of neurokinin A. Neuropeptides, 13, 263–270.
29. ROVERO, P., PESTELLINI, V., MAGGI, C.A., PATACCHINI, R., REGOLI, D. & GIACHETTI, A. (1990). An highly selective NK‐2 tachykinin receptor antagonist containing D‐tryptophan. Eur. J. Pharmacol., 175, 113–115.
30. SMITH, T.K. & FURNESS, J.B. (1988). Reflex changes in circular muscle activity elicited by stroking the mucosa: an electrophysiological analysis in the isolated guinea‐pig ileum. J. Autonom. Nerv. System, 25, 205–218.
31. TOO, H.P., CORDOVA, J.L. & MAGGIO, J.E. (1989). A novel radioimmunoassay for neuromedin K. I Absence of neuromedin K‐like immunoreactivity in guinea‐pig ileum and urinary bladder. II Heterogeneity of tachykinins in guinea‐pig tissues. Regul. Peptides, 26, 93–105.
32. TURNER, A.J. (1987). Neuropeptides and their Peptidases. Chichester: Ellis Horwood Ltd.