Ranolazine—a new drug with beneficial effects on renal preservation

Transplantation

Volumn 50, Issue 5, 1990, Pages 755-759

  Lodge, J Peter A ^a   Lam, For T ^a   Perry, Sarah L ^a   Giles, Geoffrey R ^a  

^a ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIANGINA PECTORIS AGENT; PLACEBO; RANOLAZINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG THERAPY; INTRAARTERIAL DRUG ADMINISTRATION; KIDNEY TRANSPLANTATION; NONHUMAN; ORGAN PRESERVATION; PRIORITY JOURNAL; SURGERY; SWINE;

ANIMAL; BLOOD FLOW VELOCITY; GLOMERULAR FILTRATION RATE; KIDNEY FUNCTION TESTS; KIDNEY TRANSPLANTATION; ORGAN PRESERVATION; PIPERAZINES; SUPPORT, NON-U.S. GOV'T; SWINE; TIME FACTORS; TRANSPLANTATION, AUTOLOGOUS;

EID: 0025254674     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199011000-00004     Document Type: Article

References (22)

1. Alley MC, Alps BJ, Kilpatrick AT. The effects of the novel anti-anginal agent RS 43285 on [lactic acid], [K+] and pH in a canine model of transient myocardial ischaemia. Biochem Soc Trans 1987; 15: 1057.
2. Ferrandon P, Pascal J-C, Armstrong JM. Protective effects of the novel anti-ischaemic agent ranolazine (RS-43285) in perfused rat hearts. Proc Br J Pharmacol Soc 1988; 93: 247P.
3. Alley MC, Alps BJ. Prevention of myocardial enzyme release by ranolazine in a primate model of ischaemia with reperfusion. Br J Pharmacol 1990; 99: 5.
4. Lam FT, Mavor AID, Potts DJ, Giles GR. Improved 72-hour renal preservation with phosphate-buffered sucrose. Transplantation 1989; 47: 767.
5. Lam FT, Ubhi CS, Mavor AID, Lodge JPA, Giles GR. Clinical evaluation of PBS140 solution for cadaveric renal preservation. Transplantation 1989; 48: 1067.
6. Lodge JPA, Perry SL, Skinner C, Potts DJ, Giles GR. Improved renal preservation with a simple extracellular solution-PBS140: comparison with hyperosmolar citrate and University of Wisconsin Solutions Transplantation (in press).
7. Pirie DC, Potts DJ. A comparison of the relative effectiveness of three preservation fluids upon the integrity and function of rabbit proximal convoluted tubules perfused in vitro. Clin Sei 1986; 70: 443.
8. Wright HK, Gann DS. An automatic anthrone method for the determination of inulin in plasma and urine. J Lab Clin Med 1966; 67: 689.
9. Thomsen K. Lithium clearance: A new method for determining proximal and distal reabsorption of sodium and water. Nephron 1984; 37: 217.
10. Brobeck JR, ed. Best and Taylor’s physiological basis of medical practice. lOth ed. Baltimore: Williams & Wilkins, 1978: 83.
11. Goldring W, Clarke RW, Smith HW. The phenol red clearance in normal man. J Clin Invest 1936; 15: 221.
12. Lam FT, Mavor AID, Giles GR. Retrospective comparative study of the influence of preservation Solutions on human allograft function and survival. Nephrol Dial Transplant 1988; 3: 300.
13. Paller MS, Hoidal JR, Ferris T. Oxygen free radicals in ischaemic acute renal failure in the rat. J Clin Invest 1984; 74: 1156.
14. Bayati A, Hellberg O, Kallslorg O, Wolgast M. Effects of scavengers towards oxygen-free radicals in rat kidneys subjected to ischaemic damage. Transplant Proc 1986; 18: 84.
15. Koyama I, Bulkley GB, Williams GM, Im MJ. The role of oxygen free radicals in mediating the reperfusion injury of cold-preserved ischaemic kidneys. Transplantation 1985; 12: 590.
16. Sperber I. Studies on the mammalian kidney. Zool Bidrag Fran 1944; 22: 249.
17. Nielsen TW, Maaske CA, Booth NH. Some comparative aspects of porcine renal function. In: Bustad LK, McClellan RO, eds. Swine in biomedical research. Seattle: Frayn, 1966: 529.
18. Kreis H, Lacombe M, Ciancioni C, Marinov V. 48-hour kidney preservation: Initial perfusion with potassium-rich solution. Rev Europ Etudes Clin et Biol 1972; 17: 192.
19. Ploeg RJ, Goossens D, McAnulty JF, Southard JH, Beizer OF. Successful 72-hour cold storage of dog kidneys with UW solution. Transplantation 1988; 46: 191.
20. Ariyan S, Romolo JL, Jacobs JR, et al. A simple ex vivo method for evaluating the function of preserved kidneys. Arch Surg 1971; 102: 57.
21. Shapiro JI, Cheung C, Itabashi A, Chan L, Schrier RW. The effect of verapamil on renal function after warm and cold ischaemia in the isolated perfused rat kidney. Transplantation 1985; 40: 596.
22. Anaise D, Lane B, Waltzer WC, Rapaport FT. The protective effect of calcium inhibitors and of captopril on the renal micro-circulation during reperfusion. Transplantation 1987; 43: 128.