Inhibition of cGMP-dependent protein kinase by (Rp)-guanosine 3',5'-monophosphorothioates

FEBS Letters

Volumn 263, Issue 1, 1990, Pages 47-50

  Butt, Elke ^a   Van Bemmelen, Michael ^a   Fischer, Lilo ^b   Walter, Ulrich ^b   Jastorff, Bernd ^a  

^a UNIVERSITY OF BREMEN   (Germany)

^b Labor für Klinische Biochemie Medizinische Universitätsklinik Josef Schneider Str 2 D 8700 Würzburg FRG ^*

Author keywords

8 Cl cGMPS; Antagonist; cGMPS; Protein kinase, cGMP dependent

Indexed keywords

CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; GUANOSINE DERIVATIVE; PROTEIN KINASE;

ARTICLE; ENZYME INHIBITION; PRIORITY JOURNAL;

ANIMAL; CATTLE; CYCLIC GMP; ENZYME ACTIVATION; KINETICS; LUNG; MOLECULAR STRUCTURE; MYOCARDIUM; PROTEIN KINASES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T; THIONUCLEOTIDES;

EID: 0025250329     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-5793(90)80702-K     Document Type: Article

References (26)

1. Interaction of hydrolysis-resistant analogs of cyclic GMP with the phosphodiesterase and light-sensitive channel of retinal rod outer segments.
2. Hydrolysis of cyclic nucleotides by a purified cGMP-stimulated phosphodiesterase: structural requirements for hydrolysis
3. Stoichiometric and reversible phosphorylation of a 46-kDa protein in human platelets in response to cGMP- and cAMP-elevating vasodilators.