The effects of dizocilpine maleate (MK-801), an antagonist of the n-methyl-d-aspartate receptor, on neurologic recovery and histopathology following complete cerebral ischemia in primates

Journal of Cerebral Blood Flow and Metabolism

Volumn 10, Issue 2, 1990, Pages 252-261

  Lanier, William L ^a,d   Perkins, William J ^a   Karlsson, Bente R ^c   Milde, James H ^a   Scheithauer, Bernd W ^a   Shearman, Gary T ^b   Michenfelder, John D ^a  

^a MAYO CLINIC COLLEGE OF MEDICINE   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c UNIVERSITY OF OSLO   (Norway)

^d MAYO CLINIC   (United States)

Author keywords

Brain resuscitation; Complete cerebral ischemia; Dizocilpine maleate (MK 801); Excitatory amino acid (EAA); Excitatory amino acid antagonist; Hippocampal histopathology; L glutamate antagonist; NMDA antagonist

Indexed keywords

DIZOCILIPINE MALEATE; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN ISCHEMIA; HIPPOCAMPUS; HISTOLOGY; HISTOPATHOLOGY; MONKEY; NERVE CELL LESION; NONHUMAN; PRIORITY JOURNAL;

ANIMAL; BRAIN; DIBENZOCYCLOHEPTENES; DIZOCILPINE MALEATE; ELECTROENCEPHALOGRAPHY; HIPPOCAMPUS; ISCHEMIC ATTACK, TRANSIENT; MACACA NEMESTRINA; MALE; PILOT PROJECTS; RECEPTORS, N-METHYL-D-ASPARTATE; RECEPTORS, NEUROTRANSMITTER; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0025248462     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/jcbfm.1990.42     Document Type: Article

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