Deficiencies of Coagulation-Inhibiting and Fibrinolytic Proteins in Outpatients with Deep-Vein Thrombosis

New England Journal of Medicine

Volumn 323, Issue 22, 1990, Pages 1512-1516

  Heijboer, Harriët ^a   Brandjes, Desiderius P m ^a   Büller, Harry R ^a   Sturk, Augueste ^a   Ten Cate, Jan Wouter ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

PLASMINOGEN; PROTEIN C; PROTEIN S;

ADULT; ANTITHROMBIN III DEFICIENCY; ARTICLE; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; FAMILIAL DISEASE; FEMALE; HUMAN; JUVENILE; MAJOR CLINICAL STUDY; MALE; PREDICTION; PREVALENCE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; RECURRENT DISEASE;

ACUTE DISEASE; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTITHROMBIN III; ANTITHROMBIN III DEFICIENCY; FEMALE; GLYCOPROTEINS; HUMAN; MALE; MIDDLE AGE; PLASMINOGEN; PREDICTIVE VALUE OF TESTS; PROTEIN C; PROTEIN S; SUPPORT, NON-U.S. GOV'T; THROMBOPHLEBITIS;

EID: 0025241268     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJM199011293232202     Document Type: Article

References (30)

1. Kierkegaard A. Incidence of acute deep vein thrombosis in two districts: a phlebographic study. Acta Chir Scand 1980; 146: 267–9.
2. Egeberg O. Inherited antithrombin deficiency causing thrombophilia. Thromb Diath Haemorrh 1965; 13: 516–30.
3. Marciniak E, Farley CH, DeSimone PA. Familial thrombosis due to antithrombin 3 deficiency. Blood 1974; 43: 219–31.
4. Bauer KA, Rosenberg RD. Congenital antithrombin III deficiency: insights into the pathogenesis of the hypercoagulable state and its management using markers of hemostatic system activation. Am J Med 1989; 87: Suppl 3B: 39S–43S.
5. Bauer KA, Goodman TL, Kass BL, Rosenberg RD. Elevated factor Xa activity in the blood of asymptomatic patients with congenital antithrombin deficiency. J Clin Invest 1985; 76: 826–36.
6. Rosenberg RD, Bauer KA. Thrombosis in inherited deficiencies of antithrombin, protein C, and protein S. Hum Pathol 1987; 18: 253–62.
7. Griffin JH, Evatt B, Zimmerman TS, Kleiss AJ, Wideman C. Deficiency of protein C in congenital thrombotic disease. J Clin Invest 1981; 68: 1370–3.
8. Broekmans AW, Veltkamp JJ, Bertina RM. Congenital protein C deficiency and venous thromboembolism: a study of three Dutch families. N Engl J Med 1983; 309: 340–4.
9. Schafer AI. The hypercoagulable states. Ann Intern Med 1985; 102: 814–28.
10. Horellou MH, Conard J, Bertina RM, Samama M. Congenital protein C deficiency and thrombotic disease in nine French families. BMJ 1984; 289: 1285–7.
11. Comp PC, Esmon CT. Recurrent venous thromboembolism in patients with a partial deficiency of protein S. N Engl J Med 1984; 311: 1525–8.
12. Broekmans AW, Bertina RM, Reinalda-Poot J, et al. Hereditary protein S deficiency and venous thrombo-embolism: a study in three Dutch families. Thromb Haemost 1985; 53: 273–7.
13. Engesser L, Broekmans AW, Briët E, Brommer EJP, Bertina RM. Hereditary protein S deficiency: clinical manifestations. Ann Intern Med 1987; 106: 677–82.
14. Aoki N, Moroi M, Sakata Y, Yoshida N. Abnormal plasminogen: a hereditary molecular abnormality found in a patient with recurrent thrombosis. J Clin Invest 1978; 61: 1186–95.
15. Hasegawa DK, Tyler BJ, Nilson JR. Thrombotic disease in three families with inherited plasminogen deficiency. Blood 1982; 60: Suppl I: 213. abstract.
16. Comp PC. Hereditary disorders predisposing to thrombosis. Prog Hemost Thromb 1986; 8: 71–102.
17. Mannucci PM, Tripodi A. Laboratory screening of inherited thrombotic syndromes. Thromb Haemost 1987; 57: 247–51.
18. Vikydal R, Korninger C, Kyrle PA, et al. The prevalence of hereditary antithrombin-III deficiency in patients with a history of venous thromboembolism. Thromb Haemost 1985; 54: 744–5.
19. Ben-Tal O, Zivelin A, Seligsohn U. The relative frequency of hereditary thrombotic disorders among 107 patients with thrombophilia in Israel. Thromb Haemost 1989; 61: 50–4.
20. Gladson CL, Scharrer I, Hach V, Beck KH, Griffin JH. The frequency of type I heterozygous protein S and protein C deficiency in 141 unrelated young patients with venous thrombosis. Thromb Haemost 1988; 59: 18–22.
21. Gladson CL, Griffin JH, Hach V, Beck KH, Scharrer I. The incidence of protein C and protein S deficiency in young thrombotic patients. Blood 1985; 66: Suppl I: 350a. abstract.
22. Briët E, Engesser L, Brommer EJP, Broekmans AW, Bertina RM. Thrombophilia: its causes and a rough estimate of its prevalence. Thromb Haemost 1987; 58: 39. abstract.
23. Hull R, van Aken WG, Hirsh J, et al. Impedance plethysmography using the occlusive cuff technique in the diagnosis of venous thrombosis. Circulation 1976; 53: 696–700.
24. Hull RD, Hirsh J, Carter CJ, et al. Diagnostic efficacy of impedance plethysmography for clinically suspected deep-vein thrombosis: a randomized trial. Ann Intern Med 1985; 102: 21–8.
25. Huisman MV, Büller HR, ten Cate JW, Vreeken J. Serial impedance plethysmography for suspected deep venous thrombosis in outpatients: the Amsterdam general practitioner study. N Engl J Med 1986; 314: 823–8.
26. Huisman MV, Büller HR, ten Cate JW, Heijermans HS, van der Laan J. van Maanen DJ. Management of clinically suspected acute venous thrombosis in outpatients with serial impedance plethysmography in a community hospital setting. Arch Intern Med 1989; 149: 511–3.
27. Peters M, Breederveld C, Kahlé LH, ten Cate JW. Rapid microanalysis of coagulation parameters by automated chromogenic substrate methods —application in neonatal patients. Thromb Res 1982; 28: 773–81.
28. Sturk A, Morriën-Salomons WM, Huisman MV, Borm JJ, Büller HR, ten Cate JW. Analytical and clinical evaluation of commercial protein C assays. Clin Chim Acta 1987; 165: 263–70.
29. Miettinen OS. Individual matching with multiple controls in the case of all-or-none responses. Biometrics 1969; 25: 339–55.
30. Miletich J, Sherman L, Broze G Jr. Absence of thrombosis in subjects with heterozygous protein C deficiency. N Engl J Med 1987; 317: 991–6.