The human α2-macroglobulin receptor: Identification of a 420-kD cell surface glycoprotein specific for the activated conformation of α2-macroglobulin

Journal of Cell Biology

Volumn 110, Issue 4, 1990, Pages 1041-1048

  Ashcom, James D ^a   Tiller, Steven E ^a   Dickerson, Kenneth ^a   Cravens, Janet L ^a   Argraves, W Scott ^a   Strickland, Dudley K ^a  

^a HOLLAND LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRITICUM AESTIVUM;

ALPHA 2 MACROGLOBULIN; MEMBRANE RECEPTOR;

ARTICLE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN CONFORMATION;

ALPHA-MACROGLOBULINS; ANIMAL; CELL LINE; CHROMATOGRAPHY, AFFINITY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; HUMAN; KINETICS; LDL-RECEPTOR RELATED PROTEIN 1; MEMBRANE GLYCOPROTEINS; MOLECULAR WEIGHT; PLACENTA; PREGNANCY; PROTEIN CONFORMATION; RECEPTORS, IMMUNOLOGIC; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0025231645     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.110.4.1041     Document Type: Article

References (55)

1. Barak, L. S., and W. W. Webb. 1981. Fluorescent low density lipoprotein for observation of dynamics of individual receptor complexes on cultured human fibroblasts. J. Cell Biol. 90:595-604.
2. 2-macroglobulin. Methods Enzymol. 80:737-754.
3. 2-macroglobulin molecule. Biochem J. 181:401-418.
4. 2-macroglobulin on reaction with primary amines or proteolytic enzymes. Biochem J. 207:347-356.
5. Brown, M. S., R. G. W. Anderson, and J. L. Goldstein. 1983. Recycling receptors: the round trip itinerary of migrant membrane proteins. Cell. 32:663-667.
6. Cheng, S. Y., F. R. Maxfield, J. Robbins, M. C. Willingham, and I. H. Pastan. 1980. Receptor-mediated uptake of 3,3′,5-triiodo-L-thyronine by cultured fibroblasts. Proc. Natl. Acad. Sci. USA. 77:3425-3426.
7. 2-macroglobulin is a binding protein for basic fibroblast growth factor. J. Biol. Chem. 264:7210-7216.
8. 2-macroglobulin adsorbed to colloidal gold: a new probe in the study of receptor-mediated endocytosis. J. Cell Biol. 89:29-34.
9. 2-macroglobulin by cultured fibroblasts. J. Biol. Chem. 256:3454-3459.
10. Engvall, E., and P. Pearlman. 1972. Enzyme-linked immunosorbent assay, ELISA. III. Quantification of specific antibodies by enzyme labeled anti-immunoglobulin in antigen-coated tubes. J. Immunol. 109:129-135.
11. 2-macroglobulin to hepatocytes: mechanism of in vivo clearance. Biochem. Biophys. Res. Commun 128:795-802.
12. 2-macroglobulin receptor from diploid human fibroblasts. Biochem. J. 214:629-631.
13. 2-macroglobulin-trypsin complexes in rat hepatocytes. Biochem. Biophys. Acta. 855:49-57.
14. 2-macroglobulin-trypsin complex in rat adipocytes: evidence for different pathways. Biochem. Biophys. Acta. 845:124-130.
15. Gliemann, J., O. Davidsen, and S. K. Moestrup. 1989. Characterization, size estimation and solubilization of alpha-macroglobulin complex receptors in liver membranes. Biochem. Biophys. Acta. 980:326-332.
16. 2-macroglobulin following reaction with methylamine and trypsin. Biochem. Biophys. Acta. 705:306-314.
17. 2-macroglobulin binding to cultured fibroblasts: identification by affinity chromatography of high-affinity binding sites. Arch. Biochem. Biophys. 227:570-579.
18. 2-macroglobulin binding to cultured fibroblasts: solubilization and partial purification of binding sites. J. Biol. Chem. 258:370-377.
19. 2-macroglobulin binding and uptake. J. Biol. Chem. 261:16732-16737.
20. Hanover, J. A., M. C. Willingham, and I. Pastan. 1984. Kinetics of transit of transferrin and epidermal growth factor through clathrin-coated membranes. Cell. 39:283-293.
21. Herz, J., U. Hamann, S. Rogne, O. Myklebost, H. Gausepohl, and K. K. Stanley. 1989. Surface location and high affinity for calcium of a 500-kDa liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor. EMBO (Eur. Mol. Biol. Organ.) J. 7:4119-4127.
22. 2-macroglobulin. Proc. Natl. Acad. Sci. USA. 81:342-346.
23. 2-macroglobulin. J. Biol. Chem. 256:8134-8139.
24. Ingham, K. C., S. A. Brew, and B. S. Isaacs. 1988. Interaction of fibronectin and its gelatin-binding domains with fluorescent-labeled chains of type I collagen. J. Biol. Chem. 263:4624-4628.
25. 2-macroglobulin receptor recognition site. J. Biol. Chem. 263:6709-6714.
26. 2-macroglobulin receptors from human, baboon, rat, and mouse liver. Biochem. Arch. 5:171-176.
27. Jensen, P. H., O. Davidsen, J. Gliemann, and C. M. Petersen. 1988. Cell association and degradation of pregnancy zone protein-chymotrypsin complex in cultured human monocytes. Scand. J. Clin. Lab. Invest. 48:165-176.
28. 2-macroglobulin- and pregnancy zone protein-proteinase complexes in the human placental syncytiotrophoblast. Placenta. 9:463-477.
29. Kaplan, J., and E. A. Keogh. 1981. Analysis of the effect of amines on inhibition of receptor-mediated and fluid-phase pinocytosis in rabbit alveolar macrophages. Cell. 24:925-932.
30. 2-macroglobulin-protease complexes. Ann. NY Acad. Sci. 421:442-456.
31. 2-macroglobulin-protease complexes to rabbit alveolar macrophages. J. Biol. Chem. 254:7323-7328.
32. 2-macroglobulin-protease complex receptor. J. Biol. Chem. 256:7705-7707.
33. Klickstein, L. B., W. W. Wong, J. A. Smith, J. H. Weis, J. G. Wilson, and D. T. Fearon. 1987. Human C3b/C4b receptor (CR1): demonstration of long homologous repeating domains that are composed of the short consensus repeats characteristic of C3/C4 binding proteins. J. Exp. Med. 165:1095-1112.
34. 2-macroglobulin complexes inhibits receptor-mediated endocytosis. J. Immunol. 127: 1782-1786.
35. 2-macroglobulin receptor from human fibroblasts. J. Biol. Chem. 259:7075-7079.
36. Maxfield, F. R. 1982. Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts. J. Cell Biol. 95:676-681.
37. 2-macroglobulin. Biochemistry. 20:5353-5358.
38. 2-macroglobulin receptor as an approximately 440 kDa single chain protein. J. Biol. Chem. 264:15574-15577.
39. Munson, P. J., and D. Rodbard. 1980. LIGAND: a versatile computerized approach for the characterization of ligand binding systems. Anal. Biochem. 107:220-239.
40. 2-macroglobulin to 3T3-L1 cells after differentiation to adipocytes. Biochemistry. 23:3395-3403.
41. 2-macroglobulin. J. Biol. Chem. 262:14090-14099.
42. 2-macroglobulin and pregnancy zone protein-proteinase complexes. Eur. J. Clin. Invest. 18:184-190.
43. Pytela, R., M. D. Pierschbacher, W. S. Argraves, S. Suzuki, and E. Ruoslahti. 1987. Arginine-glycine-aspartate adhesion receptors. Methods Enzymol. 144:475-489.
44. Schneider, C., R. Sutherland, R. Newman, and M. Greaves. 1982. Structural features of the cell surface receptor for transferrin that is recognized by the monoclonal antibody OKT9. J. Biol. Chem. 257:8516-8522.
45. Schneider, W. J., U. Beisiegel, J. L. Goldstein, and M. S. Brown. 1982. Purification of the low density lipoprotein receptor, an acidic glycoprotein of 164,000 molecular weight. J. Biol. Chem. 257:2664-2673.
46. Siegel, T. W., S. Ganguly, S. Jacobs, O. M. Rosen, and C. S. Rubin. 1981. Purification and properties of the human placental insulin receptor. J. Biol. Chem. 256:9266-9273.
47. 2-macroglobulin and complement components C3 and C4. Proc. Natl. Acad. Sci. USA. 82:9-13.
48. 2-macroglobulin to human blood monocytes. Biochemistry. 27:2885-2890.
49. 2-macroglobulin. Biochemistry. 23:3115.
50. 2-macroglobulin: use for the purification and characterization of binary proteinase-inhibitor complexes. Biochemistry. 27:1458-1466.
51. Turkewitz, A. P., J. F. Amatruda, D. Borhani, S. C. Harrison, and A. L. Schwartz. 1988. A high yield purification of the human transferrin receptor and properties of its major extracellular fragment. J. Biol. Chem. 263:8318-8325.
52. 2-macroglobulin receptor in human fibroblasts, absent in tumor-derived cell lines. J. Biol. Chem. 254:5155-5160.
53. 2-macroglobulin: isolation after limited proteolysis with a bacterial proteinase. J. Biol. Chem. 261:11369-11373.
54. 2-macroglobulin binding to the plasma membrane of cultured fibroblasts: diffuse binding followed by clustering in coated regions. J. Cell Biol. 82:614-625.
55. 2-macroglobulin in cultured fibroblasts. J. Histochem. Cytochem. 28:818-823.