Effects of selective phosphodiesterase inhibitors on the polymorphonuclear leukocyte respiratory burst

The Journal of Allergy and Clinical Immunology

Volumn 86, Issue 5, 1990, Pages 801-808

  Nielson, Christopher P ^a   Vestal, Robert E ^a   Sturm, Robert J ^a   Heaslip, Richard ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

4 (3 BUTOXY 4 METHOXYBENZYL) 2 IMIDAZOLIDINONE; CALCIMYCIN; CYCLIC AMP; ENPROFYLLINE; IMAZODAN; ISOPRENALINE; MILRINONE; PHOSPHODIESTERASE; ROLIPRAM; THEOPHYLLINE; ZAPRINAST;

ARTICLE; HUMAN; HUMAN CELL; NEUTROPHIL; NORMAL HUMAN; PRIORITY JOURNAL; RESPIRATORY BURST;

ADRENERGIC BETA-AGONISTS; ADULT; CALCIMYCIN; CHROMATOGRAPHY, ION EXCHANGE; HUMAN; ISOENZYMES; ISOPROTERENOL; MIDDLE AGE; MILRINONE; NEUTROPHILS; OXYGEN CONSUMPTION; PHOSPHODIESTERASE INHIBITORS; PHOSPHORIC DIESTER HYDROLASES; PURINONES; PYRIDAZINES; PYRIDONES; PYRROLIDINONES; RO 20-1724; ROLIPRAM; SUPEROXIDES; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0025225659     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(05)80186-1     Document Type: Article

References (35)

1. The respiratory burst of phagocytes
2. Oxygen metabolism and the toxic properties of phagocytes
3. The inflammatory reaction in the airways in an animal model of the late asthmatic response
4. Beta-adrenergic modulation of the polymorphonuclear leukocyte respiratory burst is dependent upon the mechanism of cell activation
5. Adenosine: a physiologic modulator of superoxide anion generation by human neutrophils. Adenosine acts via an A2 receptor on human neutrophils
6. 2, forskolin, and dibutyryl cAMP on arachidonic acid release and inositol phospholipid metabolism in guinea pig neutrophils
7. Polymorphonuclear leukocyte inhibition by therapeutic concentrations of theophylline is mediated by cyclic-3′, 5′-adenosine monophosphate
8. Cyclic nucleotide-dependent protein kinases in airway smooth muscle
9. Multiple isozymes of cyclic nucleotide phosphodiesterase
10. Tissue specificity of cAMP-phosphodiesterase inhibitors: rolipram, amrinone, milrinone, enoximone, piroximone, and imazodan
11. Separation of leukocytes from blood and bone marrow
12. Lucigenin chemiluminescence in the assessment of neutrophil superoxide production
13. Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand, and physiological dose-response curves
14. An algorithm for the least-squares estimation of non-linear parameters
15. Assay of cyclic nucleotide phosphodiesterase and resolution of multiple molecular forms of the enzyme
16. Cyclic AMP inhibition of phosphoinositide turn-over in human neutrophils
17. Elevated leukocyte phosphodiesterase as a basis for depressed cyclic adenosine monophosphate responses in the Basenji greyhound dog model of asthma
18. Multiple molecular forms of cyclic nucleotide phosphodiesterase in cardiac and smooth muscle and in platelets. Isolation, characterization, and effects of various reference phosphodiesterase inhibitors and cardiotonic agents
19. Occupancy of adenosine receptors raises cyclic AMP alone and in synergy with occupancy of chemoattractant receptors and inhibits membrane depolarization
20. Identification and characterization of surface receptors for histamine in the human promyelocytic leukemia cell line HL-60: comparison with human peripheral neutrophils
21. The identification of a new cyclic nucleotide phosphodiesterase activity in human and guinea pig cardiac ventricle
22. Cyclic AMP-dependent regulation of lipid mediators in white cells a unifying concept for explaining the efficacy of theophylline in asthma
23. Induction of a transient elevation in intracellular levels of adenosine 3,5-cyclic monophosphate by chemotactic factors: an early event in human neutrophil activation
24. Tracheal relaxant and cardiostimulant actions of xanthines can be differentiated from diuretic and CNS-stimulant effects: role of adenosine antagonism
25. Effects of enprofylline and theophylline may show the role of adenosine
26. Inhibition of human phosphodiesterase activity by therapeutic levels of theophylline
27. Therapeutic concentrations of theophylline and enprofylline potentiate catecholamine effects and inhibit leukocyte activation
28. Biochemical regulation of airway smooth muscle tone: current knowledge and therapeutic implications
29. The effect of theophylline and enprofylline on allergen-induced bronchoconstriction
30. Inflammation and asthma
31. 4 induces airway hyperresponsiveness in dogs
32. The requirement for polymorphonuclear leukocytes in the late asthmatic response and heightened airways reactivity in an animal model
33. Activity of cyclic AMP phosphodiesterase and methyltransferases in leukocyte membranes from allergic patients
34. Subclasses of cyclic AMP-specific phosphodiesterase in left ventricular muscle and their involvement in regulating myocardial contractility
35. Assessment of selective inhibition of rat cerebral cortical calcium-independent and calcium-dependent phosphodiesterases in crude extracts using doxycyclic AMP and potassium ions