Patterns of expression of the p53 tumour suppressor in human breast tissues and tumours in situ and in vitro

International Journal of Cancer

Volumn 46, Issue 5, 1990, Pages 839-844

  Bártek, Jiří ^a   Bártková, Jiřina ^a   Vojtěšek, Bořivoj ^a   Stašková, Zdenka ^a   Rejthar, Aleš ^a   Kovařík, Jan ^a   Lane, David P ^b  

^a Research Institute of Clinical and Experimental Oncology ^*

^b Clare Hall Laboratories ^*  (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN EXPRESSION; ARTICLE; BREAST CANCER; BREAST DISEASE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

ANTIBODIES, MONOCLONAL; BREAST; BREAST DISEASES; BREAST NEOPLASMS; CARCINOMA IN SITU; CELLS, CULTURED; EPITHELIUM; FEMALE; GENE EXPRESSION; GENES, TUMOR SUPPRESSOR; HUMAN; IMMUNOHISTOCHEMISTRY; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PROTEIN P53; TUMOR CELLS, CULTURED;

EID: 0025221197     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.2910460515     Document Type: Article

References (20)

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4. A subclass of luminal epithelial cells in the human mammary gland defined by antibodies to cytokeratins
5. Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines
6. p53 expression in breast cancer
7. The cellular protein p53 in human tumors
8. Activating mutations for transformation by p53 produce a gene product that forms an hsc70‐p53 complex with an altered half life
9. Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form
10. Monoclonal antibodies specific for simian virus 40 tumor antigens
11. Increased expression of mutant forms of p53 oncogene in primary lung cancer
12. p53: oncogene or anti‐oncogene
13. Allele loss on short arm of chromosome 17 in breast cancers
14. Mutations in the p53 gene occur in diverse human tumour types
15. Post translational regulation of the 54K cellular tumor antigen in normal and transformed cells
16. Growth of normal human mammary cells in culture
17. p53: A frequent target for genetic abnormalities in lung cancer
18. Precise epitope mapping of the murine transformation‐associated protein, p53