-
1
-
-
0000206049
-
5-Azacytidine stimulates fetal hemoglobin synthesis in anemic baboons
-
DeSimone J, Heller P, Hall L, Zwiers D. 5-Azacytidine stimulates fetal hemoglobin synthesis in anemic baboons. Proc Natl Acad Sci U S A 1982; 79: 4428–31.
-
(1982)
Proc Natl Acad Sci U S A
, vol.79
, pp. 4428-4431
-
-
DeSimone, J.1
Heller, P.2
Hall, L.3
Zwiers, D.4
-
2
-
-
0020466344
-
+ thalassemia
-
Ley TJ, DeSimone J, Anagnou NP, et al. 5-Azacytidine selectively increases γ-globin synthesis in a patient with β+ thalassemia. N Engl J Med 1982; 307: 1469–75.
-
(1982)
N Engl J Med
, vol.307
, pp. 1469-1475
-
-
Ley, T.J.1
DeSimone, J.2
Anagnou, N.P.3
-
3
-
-
0020563258
-
5-Azacytidine increases γ-globin synthesis and reduces the proportion of dense cells in patients with sickle cell anemia
-
Ley TJ, DeSimone J, Noguchi CT, et al. 5-Azacytidine increases γ-globin synthesis and reduces the proportion of dense cells in patients with sickle cell anemia. Blood 1983; 62: 370–80.
-
(1983)
Blood
, vol.62
, pp. 370-380
-
-
Ley, T.J.1
DeSimone, J.2
Noguchi, C.T.3
-
4
-
-
0004959517
-
Treatment of sickle cell anemia with 5-azacytidine results in increased fetal hemoglobin production and is associated with nonrandom hypomethylation of DNA around the gamma-delta-beta-globin gene complex
-
Charache S, Dover G, Smith K, Talbot CC Jr, Moyer M, Boyer S. Treatment of sickle cell anemia with 5-azacytidine results in increased fetal hemoglobin production and is associated with nonrandom hypomethylation of DNA around the gamma-delta-beta-globin gene complex. Proc Natl Acad Sci U S A 1983; 80: 4842–6.
-
(1983)
Proc Natl Acad Sci U S A
, vol.80
, pp. 4842-4846
-
-
Charache, S.1
Dover, G.2
Smith, K.3
Talbot, C.C.4
Moyer, M.5
Boyer, S.6
-
5
-
-
0023215591
-
Erythrocyte membrane skeleton abnormalities in severe β-thalassemia
-
Shinar E, Shalev O, Rachmilewitz EA. Schrier SL. Erythrocyte membrane skeleton abnormalities in severe β-thalassemia. Blood 1987; 70: 158–64.
-
(1987)
Blood
, vol.70
, pp. 158-164
-
-
Shinar, E.1
Shalev, O.2
Rachmilewitz, E.A.3
Schrier, S.L.4
-
6
-
-
0001497750
-
Sickle cell anemia
-
In: Stamatoyannopoulos G, Nienhuis AW, Leder P, Majerus PW., The molecular basis of blood diseases. Philadelphia: W.B. Saunders
-
Schechter AN. Noguchi CT, Rodgers GP. Sickle cell anemia. In: Stamatoyannopoulos G, Nienhuis AW, Leder P, Majerus PW. eds. The molecular basis of blood diseases. Philadelphia: W.B. Saunders, 1987:179–218.
-
(1987)
eds
, pp. 179-218
-
-
Schechter, A.N.1
Noguchi, C.T.2
Rodgers, G.P.3
-
7
-
-
0021286875
-
Hydroxyurea enhances fetal hemoglobin production in sickle cell anemia
-
Platt OS, Orkin SH, Dover G, Beardsley GP, Miller B, Nathan DG. Hydroxyurea enhances fetal hemoglobin production in sickle cell anemia. J Clin Invest 1984; 74: 652–6.
-
(1984)
J Clin Invest
, vol.74
, pp. 652-656
-
-
Platt, O.S.1
Orkin, S.H.2
Dover, G.3
Beardsley, G.P.4
Miller, B.5
Nathan, D.G.6
-
8
-
-
0022354852
-
Stimulation of F-cell production in patients with sickle-cell anemia treated with cytarabine or hydroxyurea
-
Veith R, Galanello R, Papayannopoulou T, Stamatoyannopoulos G. Stimulation of F-cell production in patients with sickle-cell anemia treated with cytarabine or hydroxyurea. N Engl J Med 1985; 313: 1571–5.
-
(1985)
N Engl J Med
, vol.313
, pp. 1571-1575
-
-
Veith, R.1
Galanello, R.2
Papayannopoulou, T.3
Stamatoyannopoulos, G.4
-
9
-
-
0022568850
-
Hydroxyurea induction of hemoglobin F production in sickle cell disease: relationship between cytotoxicity and F cell production
-
Dover GJ, Humphries RK, Moore JG, et al. Hydroxyurea induction of hemoglobin F production in sickle cell disease: relationship between cytotoxicity and F cell production. Blood 1986; 67: 735–8.
-
(1986)
Blood
, vol.67
, pp. 735-738
-
-
Dover, G.J.1
Humphries, R.K.2
Moore, J.G.3
-
10
-
-
0023130331
-
Hydroxyurea-induced augmentation of fetal hemoglobin production in patients with sickle cell anemia
-
Charache S, Dover GJ, Moyer MA, Moore JW. Hydroxyurea-induced augmentation of fetal hemoglobin production in patients with sickle cell anemia. Blood 1987; 69: 109–16.
-
(1987)
Blood
, vol.69
, pp. 109-116
-
-
Charache, S.1
Dover, G.J.2
Moyer, M.A.3
Moore, J.W.4
-
11
-
-
0024838303
-
Induction of fetal hemoglobin in sickle cell patients by hydroxyurea: the N.I.H. experience
-
In: Stamatoyannopoulos G, Nienhuis AW, eds., of Progress in clinical and biological research. New York: Alan R. Liss
-
Rodgers GP, Dover GJ, Noguchi CT, Schechter AN, Nienhuis AW. Induction of fetal hemoglobin in sickle cell patients by hydroxyurea: the N.I.H. experience. In: Stamatoyannopoulos G, Nienhuis AW, eds. Hemoglobin switching, part B: cellular and molecular mechanisms. Vol. 316B of Progress in clinical and biological research. New York: Alan R. Liss, 1989:281–93.
-
(1989)
Hemoglobin switching, part B: cellular and molecular mechanisms
, vol.316B
, pp. 281-293
-
-
Rodgers, G.P.1
Dover, G.J.2
Noguchi, C.T.3
Schechter, A.N.4
Nienhuis, A.W.5
-
13
-
-
0022250152
-
Cell heterogeneity in sickle cell disease: quantitation of the erythrocyte density profile
-
Rodgers GP, Schechter AN, Noguchi CT. Cell heterogeneity in sickle cell disease: quantitation of the erythrocyte density profile. J Lab Clin Med 1985; 106: 30–7.
-
(1985)
J Lab Clin Med
, vol.106
, pp. 30-37
-
-
Rodgers, G.P.1
Schechter, A.N.2
Noguchi, C.T.3
-
14
-
-
0018227087
-
Individual variation in the production and survival of F cells in sickle-cell disease
-
Dover GJ, Boyer SH, Charache S, Heintzelman K. Individual variation in the production and survival of F cells in sickle-cell disease. N Engl J Med 1978; 299: 1428–35.
-
(1978)
N Engl J Med
, vol.299
, pp. 1428-1435
-
-
Dover, G.J.1
Boyer, S.H.2
Charache, S.3
Heintzelman, K.4
-
15
-
-
0023096287
-
The cellular basis for different fetal hemoglobin levels among sickle cell individuals with two, three, and four alpha-globin genes
-
Dover GJ, Chang VT, Boyer SH, Serjeant GR, Antonarakis S, Higgs DR. The cellular basis for different fetal hemoglobin levels among sickle cell individuals with two, three, and four alpha-globin genes. Blood 1987; 69: 341–4.
-
(1987)
Blood
, vol.69
, pp. 341-344
-
-
Dover, G.J.1
Chang, V.T.2
Boyer, S.H.3
Serjeant, G.R.4
Antonarakis, S.5
Higgs, D.R.6
-
16
-
-
0021839846
-
Alpha thalassemia changes erythrocyte heterogeneity in sickle cell disease
-
Noguchi CT, Dover GJ, Rodgers GP, et al. Alpha thalassemia changes erythrocyte heterogeneity in sickle cell disease. J Clin Invest 1985; 75: 1632–7.
-
(1985)
J Clin Invest
, vol.75
, pp. 1632-1637
-
-
Noguchi, C.T.1
Dover, G.J.2
Rodgers, G.P.3
-
17
-
-
0021356075
-
Origin of the beta S-globin gene in blacks: the contribution of recurrent mutation or gene conversion or both
-
Antonarakis SE, Boehm CD, Serjeant GR, Theisen CE, Dover GJ, Kazazian HH Jr. Origin of the beta S-globin gene in blacks: the contribution of recurrent mutation or gene conversion or both. Proc Natl Acad Sci U S A 1984; 81: 853–6.
-
(1984)
Proc Natl Acad Sci U S A
, vol.81
, pp. 853-856
-
-
Antonarakis, S.E.1
Boehm, C.D.2
Serjeant, G.R.3
Theisen, C.E.4
Dover, G.J.5
Kazazian, H.H.6
-
20
-
-
0021045875
-
The intracellular polymerization of sickle hemoglobin: effects of cell heterogeneity
-
Noguchi CT, Torchia DA, Schechter AN. The intracellular polymerization of sickle hemoglobin: effects of cell heterogeneity. J Clin Invest 1983; 72: 846–52.
-
(1983)
J Clin Invest
, vol.72
, pp. 846-852
-
-
Noguchi, C.T.1
Torchia, D.A.2
Schechter, A.N.3
-
21
-
-
0022001839
-
Hematologically and genetically distinct forms of sickle cell anemia in Africa: the Senegal type and the Benin type
-
Nagel RL, Fabry ME, Pagnier J, et al. Hematologically and genetically distinct forms of sickle cell anemia in Africa: the Senegal type and the Benin type. N Engl J Med 1985; 312: 880–4.
-
(1985)
N Engl J Med
, vol.312
, pp. 880-884
-
-
Nagel, R.L.1
Fabry, M.E.2
Pagnier, J.3
-
22
-
-
0023140020
-
Molecular analysis of the high-hemoglobin-F phenotype in Saudi Arabian sickle cell anemia
-
Miller BA, Olivieri N, Salameh M, et al. Molecular analysis of the high-hemoglobin-F phenotype in Saudi Arabian sickle cell anemia. N Engl J Med 1987; 316: 244–50.
-
(1987)
N Engl J Med
, vol.316
, pp. 244-250
-
-
Miller, B.A.1
Olivieri, N.2
Salameh, M.3
-
23
-
-
0014315876
-
Irreversibly sickled erythrocytes: a consequence of the heterogeneous distribution of hemoglobin types in sickle-cell anemia
-
Bertles JF, Milner PF. Irreversibly sickled erythrocytes: a consequence of the heterogeneous distribution of hemoglobin types in sickle-cell anemia. J Clin Invest 1968; 47: 1731–41.
-
(1968)
J Clin Invest
, vol.47
, pp. 1731-1741
-
-
Bertles, J.F.1
Milner, P.F.2
-
24
-
-
0021330872
-
Augmentation of fetal-hemoglobin production in anemic monkeys by hydroxyurea
-
Letvin NL, Linch DC, Beardsley GP, Mclntyre KW, Nathan DG. Augmentation of fetal-hemoglobin production in anemic monkeys by hydroxyurea. N Engl J Med 1984; 310: 869–73.
-
(1984)
N Engl J Med
, vol.310
, pp. 869-873
-
-
Letvin, N.L.1
Linch, D.C.2
Beardsley, G.P.3
Mclntyre, K.W.4
Nathan, D.G.5
-
25
-
-
0022619760
-
On the mechanism of Hb F elevations in the baboon by erythropoietic stress and pharmacologic manipulation
-
Lavelle D, DeSimone J, Heller P, Zwiers D, Hall L. On the mechanism of Hb F elevations in the baboon by erythropoietic stress and pharmacologic manipulation. Blood 1986; 67: 1083–9.
-
(1986)
Blood
, vol.67
, pp. 1083-1089
-
-
Lavelle, D.1
DeSimone, J.2
Heller, P.3
Zwiers, D.4
Hall, L.5
-
26
-
-
0022568850
-
Hydroxyurea induction of hemoglobin F production in sickle cell disease: relationship between cytotoxicity and F cell production
-
Dover GJ, Humphries RK, Moore JG, et al. Hydroxyurea induction of hemoglobin F production in sickle cell disease: relationship between cytotoxicity and F cell production. Blood 1986; 67: 735–8.
-
(1986)
Blood
, vol.67
, pp. 735-738
-
-
Dover, G.J.1
Humphries, R.K.2
Moore, J.G.3
-
27
-
-
0021960220
-
5-Azacytidine acts directly on both erythroid precursors and progenitors to increase production of fetal hemoglobin
-
Humphries RK, Dover G, Young NS, et al. 5-Azacytidine acts directly on both erythroid precursors and progenitors to increase production of fetal hemoglobin. J Clin Invest 1985; 75: 547–57.
-
(1985)
J Clin Invest
, vol.75
, pp. 547-557
-
-
Humphries, R.K.1
Dover, G.2
Young, N.S.3
-
28
-
-
0021853293
-
The effect of hydroxyurea on hemoglobin F in patients with myeloproliferative syndromes
-
Alter BP, Gilbert HS. The effect of hydroxyurea on hemoglobin F in patients with myeloproliferative syndromes. Blood 1985; 66: 373–9.
-
(1985)
Blood
, vol.66
, pp. 373-379
-
-
Alter, B.P.1
Gilbert, H.S.2
-
29
-
-
0022479563
-
Volumetric erythrocyte macrocytosis induced by hydroxyurea
-
Burns ER, Reed LJ, Wenz B. Volumetric erythrocyte macrocytosis induced by hydroxyurea. Am J Clin Pathol 1986; 85: 337–41.
-
(1986)
Am J Clin Pathol
, vol.85
, pp. 337-341
-
-
Burns, E.R.1
Reed, L.J.2
Wenz, B.3
-
30
-
-
0021931288
-
Hemoglobin S polymerization: primary determinant of the hemolytic and clinical severity of the sickling syndromes
-
Brittenham GM, Schechter AN, Noguchi CT. Hemoglobin S polymerization: primary determinant of the hemolytic and clinical severity of the sickling syndromes. Blood 1985; 65: 183–9.
-
(1985)
Blood
, vol.65
, pp. 183-189
-
-
Brittenham, G.M.1
Schechter, A.N.2
Noguchi, C.T.3
-
31
-
-
0024822077
-
Stimulation of fetal hemoglobin production by hydroxyurea in sickle cell anemia
-
In: Stamatoyannopoulos G, Nienhuis AW, eds., of Progress in clinical and biological research. New York: Alan R. Liss
-
Dover GJ, Charache S. Stimulation of fetal hemoglobin production by hydroxyurea in sickle cell anemia. In: Stamatoyannopoulos G, Nienhuis AW, eds. Hemoglobin switching, part B: cellular and molecular mechanisms. Vol. 316B of Progress in clinical and biological research. New York: Alan R. Liss, 1989:295–306.
-
(1989)
Hemoglobin switching, part B: cellular and molecular mechanisms
, vol.316B
, pp. 295-306
-
-
Dover, G.J.1
Charache, S.2
-
32
-
-
0023255005
-
Stimulation of fetal hemoglobin synthesis by erythropoietin in baboons
-
AI-Khatti A, Veith RW, Papayannopoulou T, Fritsch EF, Goldwasser E, Stamatoyannopoulos G. Stimulation of fetal hemoglobin synthesis by erythropoietin in baboons. N Engl J Med 1987; 317: 415–20.
-
(1987)
N Engl J Med
, vol.317
, pp. 415-420
-
-
AI-Khatti, A.1
Veith, R.W.2
Papayannopoulou, T.3
Fritsch, E.F.4
Goldwasser, E.5
Stamatoyannopoulos, G.6
-
33
-
-
0024793892
-
Manipulation of HbF production with hematopoietic growth factors
-
In: Stamatoyannopoulos G, Nienhuis AW, eds., of Progress in clinical and biological research. New York: Alan R. Liss
-
McDonagh KT, Dover GJ, Donahue R, Nathan DG, Nienhuis AW. Manipulation of HbF production with hematopoietic growth factors. In: Stamatoyannopoulos G, Nienhuis AW, eds. Hemoglobin switching, part B: cellular and molecular mechanisms. Vol. 316B of Progress in clinical and biological research. New York: Alan R. Liss, 1989:307–15.
-
(1989)
Hemoglobin switching, part B: cellular and molecular mechanisms
, vol.316B
, pp. 307-315
-
-
McDonagh, K.T.1
Dover, G.J.2
Donahue, R.3
Nathan, D.G.4
Nienhuis, A.W.5
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