Proposed Mechanism for the Condensation Reaction of Citrate Synthase: 1.9-Å Structure of the Ternary Complex with Oxaloacetate and Carboxymethyl Coenzyme A

Biochemistry

Volumn 29, Issue 9, 1990, Pages 2213-2219

  Karpusas, Mihail ^a   Branchaud, Bruce ^a   Remington, S James ^a  

^a UNIVERSITY OF OREGON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CITRATE SYNTHASE; OXALOACETIC ACID;

ARTICLE; CARBOXYMETHYL COENZYME A; COMPLEX FORMATION; CRYSTAL STRUCTURE; PRIORITY JOURNAL;

ACYL COENZYME A; ANIMAL; CATALYSIS; CHEMISTRY; CHICKENS; CITRATE (SI)-SYNTHASE; HYDROGEN BONDING; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; OXALOACETATES; OXO-ACID-LYASES; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; X-RAY DIFFRACTION;

EID: 0025214122     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi00461a002     Document Type: Article

References (26)

1. Bayer, E., Bauer, B., & Eggerer, H. (1981) Eur. J. Biochem. 120, 47-52.
2. Bernstein, F. C., Koetzle, T. F., Williams, G. J. B., Meyer, E. F., Jr., Brice, M. D., Rodgers, J. R., Kennard, O., Schimanouchi, T., & Tasunmi, M. (1977) J. Mol. Biol. 112, 535-542.
3. Eggerer, H. (1965) Biochem. Z. 343, 111-138.
4. Eggerer, H., & Remberger, U. (1963) Biochem. Z. 337, 202-223.
5. Eggerer, H., Buckel, W., Lenz, H., Wunderwald, P., Cornforth, J. W., Donninger, C., Mallaby, R., Redmond, J. W., & Gottschalk, G. (1970) Nature (London) 226, 517-519.
6. Englard, S. (1958) J. Biol. Chem. 234, 1004-1009.
7. Evans, C. T., Owens, D. D., Sumegi, B., Kispal, G., & Srere, P. (1988) Biochemistry 27, 4680-4686.
8. Handford, P. A., Ner, S. S., Bloxham, D. P., & Wilton, D. C. (1988) Biochim. Biophys. Acta 953, 232-240.
9. Hanson, K. R., & Rose, I. A. (1975) Acc. Chem. Res. 8, 1-10.
10. Hegarty, A. F., & Jencks, W. P. (1975) J. Am. Chem. Soc. 97, 7188-7189.
11. House, H. O. (1972) Modern Synthetic Reactions, p 494, W. A. Benjamin, New York.
12. Jencks, W. P. (1976) Acc. Chem. Res. 9, 425-432.
13. Jencks, W. P. (1980) Acc. Chem. Res. 13, 161-169.
14. Jencks, W. P. (1981) Chem. Soc. Rev. 10, 345-375.
15. Jones, T. A. (1978) J. Appl. Crystallogr. 11, 268-272.
16. Lau, S.-M., Brantley, R. K., & Thorpe, C. (1988) Biochemistry 27, 5089-5095.
17. Lienhard, G. E., & Jenkcs, W. P. (1965) J. Am. Chem. Soc. 87, 3863-3874.
18. Loehlein-Werhahn., G., Bayer, E., Bauer, B., & Eggerer, H. (1983) Eur. J. Biochem. 133, 665-672.
19. Remington, S., Wiegand, G., & Huber, R. (1982) J. Mol. Biol. 158, 111-152.
20. Schmid, M. F., Weaver, L. H., Holmes, M. A., Gruetter, M. G., Ohlendorf, D. H., Reynolds, R. A., Remington, S. J., & Matthews, B. W. (1981) Acta Crystallogr. A37, 701-710.
21. Spector, L. B. (1972) Enzymes (3rd Ed.) 7, 357-389.
22. Srere, P. (1972) Curr. Top. Cell. Regul. 5, 245-283.
23. Tronrud, D. E., Ten Eyck, L. F., & Matthews, B. W. (1987) Acta Crystallogr. A43, 489-501.
24. Weitzman, P. D. J., & Danson, M. J. (1976) Curr. Top. Cell. Regul. 10, 161-204.
25. Wiegand, G., & Remington, S. (1986) Annu. Rev. Biophys. Biophys. Chem. 15, 97-117.
26. Wiegand, G., Remington, S., Deisenhofer, J., & Huber, R. (1984) J. Mol. Biol. 174, 205-211.* Author to whom correspondence should be addressed.