Farnesol modification of Kirsten-ras exon 4B protein is essential for transformation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 87, Issue 8, 1990, Pages 3042-3046

  Jackson, Janis H ^a   Cochrane, Charles G ^a   Bourne, Jeffrey R ^a   Solski, Patricia A ^b   Buss, Janice E ^b   Der, Channing J ^b  

^a SCRIPPS CLINIC   (United States)

^b BURNHAM INSTITUTE   (United States)

Author keywords

Carboxyl terminal processing; Isoprenylation; Membrane association; Palmitoylation

Indexed keywords

FARNESOL;

ACYLATION; ANIMAL CELL; ARTICLE; CELL CULTURE; CELL TRANSFORMATION; GENETIC TRANSFECTION; MOUSE; NONHUMAN; ONCOGENE RAS; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN MODIFICATION;

ANIMAL; ANTICHOLESTEREMIC AGENTS; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; EXONS; FARNESOL; GENETIC VECTORS; HUMAN; LOVASTATIN; MEVALONIC ACID; MICE; MUTATION; OLIGONUCLEOTIDE PROBES; PROTO-ONCOGENE PROTEIN P21(RAS); PROTO-ONCOGENE PROTEINS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TRANSFECTION;

ANIMALIA;

EID: 0025212684     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.87.8.3042     Document Type: Article

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