메뉴 건너뛰기




Volumn 1, Issue 1, 1990, Pages 13-23

Recent Advances with Monoclonal Antibody Drug Targeting for the Treatment of Human Cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DRUG CARRIER; MONOCLONAL ANTIBODY; PRODRUG;

EID: 0025200067     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc00001a002     Document Type: Article
Times cited : (65)

References (108)
  • 1
    • 85022980964 scopus 로고
    • This review was presented as a lecture at the Dedicatory Symposia for the Journal of Bioconjugates at the American Chemical Society Meeting, Dallas, Texas, April 11
    • This review was presented as a lecture at the Dedicatory Symposia for the Journal of Bioconjugates at the American Chemical Society Meeting, Dallas, Texas, April 11, 1989.
    • (1989)
  • 2
    • 85022951711 scopus 로고
    • The concept was presented as part of a lecture at the dedication of the Georg-Speyer-Haus, September 6, 1906; see: (Louis Shuster, Ed.) Little, Brown, and Company, Boston, MA
    • The concept was presented as part of a lecture at the dedication of the Georg-Speyer-Haus, September 6, 1906; see: (1962) Readings in Pharmacology (Louis Shuster, Ed.) Little, Brown, and Company, Boston, MA.
    • (1962) Readings in Pharmacology
  • 3
    • 0018200431 scopus 로고
    • The immune response genes of the major histocompatibility complex
    • Benacerraf, B. and Germain, R. N. (1978) The immune response genes of the major histocompatibility complex. Immunol. Rev. 38, 70–119.
    • (1978) Immunol. Rev. , vol.38 , pp. 70-119
    • Benacerraf, B.1    Germain, R.N.2
  • 4
    • 0020332288 scopus 로고
    • Genetics and regulation of the immune response
    • Benacerraf, B. (1982) Genetics and regulation of the immune response. Natl. Cancer Inst. Monogr. 60, 171–173.
    • (1982) Natl. Cancer Inst. Monogr. , vol.60 , pp. 171-173
    • Benacerraf, B.1
  • 5
    • 0021423257 scopus 로고
    • The interaction between class II MHC molecules and antigens as a basis for Ir gene specificity.
    • Benecerraf, B. and Rock, K. L. (1984) The interaction between class II MHC molecules and antigens as a basis for Ir gene specificity. Ann. Immunol. (Paris) 135C (3), 386–389.
    • (1984) Ann. Immunol. (Paris) , vol.135C , Issue.3 , pp. 386-389
    • Benecerraf, B.1    Rock, K.L.2
  • 7
    • 0017162482 scopus 로고
    • Recognition structures determined by the H-2 complex.
    • Snell, G. D. (1976) Recognition structures determined by the H-2 complex. Transplant. Proc. 8 (2), 147–156.
    • (1976) Transplant. Proc. , vol.8 , Issue.2 , pp. 147-156
    • Snell, G.D.1
  • 8
    • 0018200432 scopus 로고
    • T cells, T cells recognition structures, and the major histocompatibility complex
    • Snell, G. D. (1978) T cells, T cells recognition structures, and the major histocompatibility complex. Immunol. Rev. 38, 3–69.
    • (1978) Immunol. Rev. , vol.38 , pp. 3-69
    • Snell, G.D.1
  • 9
    • 0018589577 scopus 로고
    • Recent advances in histocompatibility immunogenetics
    • Snell, G. D. (1979) Recent advances in histocompatibility immunogenetics. Adv. Genet. 20, 291–355.
    • (1979) Adv. Genet. , vol.20 , pp. 291-355
    • Snell, G.D.1
  • 10
    • 0019260162 scopus 로고
    • The major histocompatibility complex: Its evolution and involvement in cellular immunity
    • Snell, G. D. (1980) The major histocompatibility complex: Its evolution and involvement in cellular immunity. Harvey Lect. 74, 49–80.
    • (1980) Harvey Lect. , vol.74 , pp. 49-80
    • Snell, G.D.1
  • 11
    • 0019465678 scopus 로고
    • Studies in histocompatibility.
    • Snell, G. D. (1981) Studies in histocompatibility. Science 213 (4504), 172–178.
    • (1981) Science , vol.213 , Issue.4504 , pp. 172-178
    • Snell, G.D.1
  • 12
    • 0019491845 scopus 로고
    • The future of immunogenetics
    • Snell, G. D. (1981) The future of immunogenetics. Prog. Clin. Biol. Res. 45, 241–272.
    • (1981) Prog. Clin. Biol. Res. , vol.45 , pp. 241-272
    • Snell, G.D.1
  • 13
    • 0017143497 scopus 로고
    • Fusion between immunoglobulin secreting and non-secreting myeloma cell lines
    • Kohler, G., Howe, S. C., and Milstein, C. (1976) Fusion between immunoglobulin secreting and non-secreting myeloma cell lines. Eur. J. Immunol. 6, 292–295.
    • (1976) Eur. J. Immunol. , vol.6 , pp. 292-295
    • Kohler, G.1    Howe, S.C.2    Milstein, C.3
  • 14
    • 0021934132 scopus 로고
    • Derivation and diversification of monoclonal antibodies. Nobel lecture.
    • Kohler, G. (1985) Derivation and diversification of monoclonal antibodies. Nobel lecture. Biosci. Rep. 5 (7), 533–549.
    • (1985) Biosci. Rep. , vol.5 , Issue.7 , pp. 533-549
    • Kohler, G.1
  • 15
    • 0022999056 scopus 로고
    • Derivation and diversification of monoclonal antibodies.
    • Kohler, G. (1986) Derivation and diversification of monoclonal antibodies. Science 233 (4770), 1281–1286.
    • (1986) Science , vol.233 , Issue.4770 , pp. 1281-1286
    • Kohler, G.1
  • 16
    • 0023897676 scopus 로고
    • Nobel lecture in physiology or medicine-1987. Somatic generation of immune diversity
    • Tonegawa, S. (1988) Nobel lecture in physiology or medicine-1987. Somatic generation of immune diversity. In Vitro Cell Dev. Biol. 24 (4), 253–265.
    • (1988) Vitro Cell Dev. Biol. , vol.24 , Issue.4 , pp. 253-265
    • Tonegawa, S.1
  • 17
    • 0018658291 scopus 로고
    • Somatic recombination and mosaic structure of immunoglobulin genes
    • Tonegawa, S. (1979–1980) Somatic recombination and mosaic structure of immunoglobulin genes. Harvey Lect. 75, 61–83.
    • (1979) Harvey Lect. , vol.75 , pp. 61-83
    • Tonegawa, S.1
  • 18
    • 0023908196 scopus 로고
    • Somatic generation of immune diversity.
    • Tonegawa, S. (1988) Somatic generation of immune diversity. Biosci. Rep. 8 (1), 3–26.
    • (1988) Biosci. Rep. , vol.8 , Issue.1 , pp. 3-26
    • Tonegawa, S.1
  • 19
    • 0023883966 scopus 로고
    • Biotechnology and medicine of the future.
    • Hood, L. (1988) Biotechnology and medicine of the future. J. Am. Med. Assoc. 259 (12), 1837–1844.
    • (1988) J. Am. Med. Assoc. , vol.259 , Issue.12 , pp. 1837-1844
    • Hood, L.1
  • 20
    • 0022332686 scopus 로고
    • Diversity in the germline antibody repertoire. Molecular evolution of the T15 VN gene family.
    • Perlmutter, R. M., Berson, B., Griffin, J. A., and Hood, L. (1985) Diversity in the germline antibody repertoire. Molecular evolution of the T15 VN gene family. J. Exp. Med. 162 (6), 1998–2016.
    • (1985) J. Exp. Med. , vol.162 , Issue.6 , pp. 1998-2016
    • Perlmutter, R.M.1    Berson, B.2    Griffin, J.A.3    Hood, L.4
  • 25
    • 0024239497 scopus 로고
    • Mouse/human chimeric antibodies to a tumor-associated antigen: Biologic activity of the four human IgG subclasses.
    • Shaw, D. R., Khazaeli, M. B., and LoBuglio, A. F. (1988) Mouse/human chimeric antibodies to a tumor-associated antigen: Biologic activity of the four human IgG subclasses. JNCI, J. Natl. Cancer Inst. 80 (19), 1553–1559.
    • (1988) JNCI, J. Natl. Cancer Inst. , vol.80 , Issue.19 , pp. 1553-1559
    • Shaw, D.R.1    Khazaeli, M.B.2    LoBuglio, A.F.3
  • 26
    • 0024040626 scopus 로고
    • Biological activity of human-mouse IgGl, IgG2, IgG3, and IgG4 chimeric monoclonal antibodies with antitumor specificity.
    • Steplewski, Z., Sun, L. K., Shearman, C. W., Ghrayeb, J., Daddona, P., and Loprowski, H. (1988) Biological activity of human-mouse IgGl, IgG2, IgG3, and IgG4 chimeric monoclonal antibodies with antitumor specificity. Proc. Natl. Acad. Sci. U.S.A. 85 (13), 4852–4856.
    • (1988) Proc. Natl. Acad. Sci. U.S.A. , vol.85 , Issue.13 , pp. 4852-4856
    • Steplewski, Z.1    Sun, L.K.2    Shearman, C.W.3    Ghrayeb, J.4    Daddona, P.5    Loprowski, H.6
  • 27
    • 0023144405 scopus 로고
    • Chimeric antibody with human constant regions and mouse variable regions directed against carcinoma-associated antigen 17–1A.
    • Sun, L. K., Curtis, P., Rakowicz-Szulczynska, E., Ghrayeb, J., Chang, N., Morrison, S. L., and Koprowski, H. (1987) Chimeric antibody with human constant regions and mouse variable regions directed against carcinoma-associated antigen 17–1A. Proc. Natl. Acad. Sci. U.S.A. 84 (1), 214–218.
    • (1987) Proc. Natl. Acad. Sci. U.S.A. , vol.84 , Issue.1 , pp. 214-218
    • Sun, L.K.1    Curtis, P.2    Rakowicz-Szulczynska, E.3    Ghrayeb, J.4    Chang, N.5    Morrison, S.L.6    Koprowski, H.7
  • 28
    • 0023184888 scopus 로고
    • Characterization of a mouse/human chimeric monoclinal antibody (17–1A) to a colon cancer tumor-associated antigen.
    • Shaw, D. R., Khazaeli, M. B., Sun, L. K., Ghrayeb, J., Daddona, P. E., McKinney, S., and LoBuglio, A. F. (1987) Characterization of a mouse/human chimeric monoclinal antibody (17–1A) to a colon cancer tumor-associated antigen. J. Immunol. 138 (12), 4534–4538.
    • (1987) J. Immunol. , vol.138 , Issue.12 , pp. 4534-4538
    • Shaw, D.R.1    Khazaeli, M.B.2    Sun, L.K.3    Ghrayeb, J.4    Daddona, P.E.5    McKinney, S.6    LoBuglio, A.F.7
  • 29
    • 0023611311 scopus 로고
    • Production of a mouse-human chimeric monoclonal antibody to CD20 with potent Fc-dependent biologic activity.
    • Liu, A. Y., Robinson, R. R., Murray, E. D., Jr., Ledbetter, J. A., Hellstrom, I., and Hellstrom, K. E. (1987) Production of a mouse-human chimeric monoclonal antibody to CD20 with potent Fc-dependent biologic activity. J. Immunol. 139 (10), 3521–3526.
    • (1987) J. Immunol. , vol.139 , Issue.10 , pp. 3521-3526
    • Liu, A.Y.1    Robinson, R.R.2    Murray, E.D.3    Ledbetter, J.A.4    Hellstrom, I.5    Hellstrom, K.E.6
  • 32
    • 0021713342 scopus 로고
    • Production of functional chimaeric mouse/human antibody.
    • Boulianne, G. L., Hozumi, N., and Shulman, M. J. (1984) Production of functional chimaeric mouse/human antibody. Nature 312 (5995), 643–646.
    • (1984) Nature , vol.312 , Issue.5995 , pp. 643-646
    • Boulianne, G.L.1    Hozumi, N.2    Shulman, M.J.3
  • 33
    • 0022253160 scopus 로고
    • Significance and biological function of class II MHC molecules. Rous-Whipple Award lecture.
    • Benecerraf, B. (1985) Significance and biological function of class II MHC molecules. Rous-Whipple Award lecture. Am. J. Pathol. 120 (3), 334–343.
    • (1985) Am. J. Pathol. , vol.120 , Issue.3 , pp. 334-343
    • Benecerraf, B.1
  • 34
  • 35
    • 0016694206 scopus 로고
    • Three-dimensional structure, function and genetic control of immunoglobulin.
    • Poljak, R. J. (1975) Three-dimensional structure, function and genetic control of immunoglobulin. Nature 256, 373.
    • (1975) Nature , vol.256 , pp. 373
    • Poljak, R.J.1
  • 36
    • 0015795362 scopus 로고
    • Molecular dissection of immunoglobulin G. Conformational interrelationships of te subunits of human immunoglobulin G.
    • Lit-man, G. W., Litman, R. S., Good, R. A., and Rosenberg, A. (1973) Molecular dissection of immunoglobulin G. Conformational interrelationships of te subunits of human immunoglobulin G. Biochemistry 12 (10), 2004–2011.
    • (1973) Biochemistry , vol.12 , Issue.10 , pp. 2004-2011
    • Lit-man, G.W.1    Litman, R.S.2    Good, R.A.3    Rosenberg, A.4
  • 37
    • 0023928566 scopus 로고
    • The contribution of constant region domains to the binding of murine IgM to Fc mu receptors on T cells.
    • Mathur, A., Lynch, R. G., and Kohler, G. (1988) The contribution of constant region domains to the binding of murine IgM to Fc mu receptors on T cells. J. Immunol 140 (1), 143–147.
    • (1988) J. Immunol , vol.140 , Issue.1 , pp. 143-147
    • Mathur, A.1    Lynch, R.G.2    Kohler, G.3
  • 38
    • 0018762006 scopus 로고
    • IgE responses of synthetic polypeptide antigens. I. Simultaneous Ir gene and isotype-spe-cific regulation of IgE responses to L-glutamic acid60-L-alanine30-L-tyrosinel0 (GAT).
    • Dessein, A., Germain, R. N., Dorf, M. E., and Benacerraf, B. (1979) IgE responses of synthetic polypeptide antigens. I. Simultaneous Ir gene and isotype-spe-cific regulation of IgE responses to L-glutamic acid60-L-alanine30-L-tyrosinel0 (GAT). J. Immunol. 123 (1), 463–470.
    • (1979) J. Immunol. , vol.123 , Issue.1 , pp. 463-470
    • Dessein, A.1    Germain, R.N.2    Dorf, M.E.3    Benacerraf, B.4
  • 39
    • 0015922120 scopus 로고
    • Structure of immunoglobulin A. Amino acid sequence of cys-teine-containing peptides from the J chain.
    • Mendez, E., Frangione, B., and Franklin, E. C. (1973) Structure of immunoglobulin A. Amino acid sequence of cys-teine-containing peptides from the J chain. Biochemistry 12 (6), 1119–1124.
    • (1973) Biochemistry , vol.12 , Issue.6 , pp. 1119-1124
    • Mendez, E.1    Frangione, B.2    Franklin, E.C.3
  • 40
    • 0015759292 scopus 로고
    • Immunoglobulin A. Arrangement of disulfide bridges in the “hinge” region of an immunoglobulin lin A-l human myeloma protein.
    • Wolfenstein-Todel, C., Prelli, F., Frangione, B., and Franklin, E. C. (1973) Immunoglobulin A. Arrangement of disulfide bridges in the “hinge” region of an immunoglobulin lin A-l human myeloma protein. Biochemistry 12 (25), 5195–5197.
    • (1973) Biochemistry , vol.12 , Issue.25 , pp. 5195-5197
    • Wolfenstein-Todel, C.1    Prelli, F.2    Frangione, B.3    Franklin, E.C.4
  • 41
    • 0019170967 scopus 로고
    • Soluble mac-romolecules as carriers for daunorubicin
    • Hurwitz, E., Wilchek, M., and Pitha, J. (1980) Soluble mac-romolecules as carriers for daunorubicin. J. Appl. Biochem. 2, 25–35.
    • (1980) J. Appl. Biochem. , vol.2 , pp. 25-35
    • Hurwitz, E.1    Wilchek, M.2    Pitha, J.3
  • 42
    • 0022556050 scopus 로고
    • Preparation of F(ab’)2 fragments from mouse IgG of various subclasses
    • Lamoyi, E. (1986) Preparation of F(ab’)2 fragments from mouse IgG of various subclasses. Methods Enzymol. 121, 652–663.
    • (1986) Methods Enzymol. , vol.121 , pp. 652-663
    • Lamoyi, E.1
  • 43
    • 0017228029 scopus 로고
    • Fb’2, a new peptic fragment of human immunoglobulin G.
    • Parr, D. M., Connell, G. E., Kells, D. I., and Hofmann, T. (1976) Fb’2, a new peptic fragment of human immunoglobulin G. Biochem. J. 155 (1), 31–36.
    • (1976) Biochem. J. , vol.155 , Issue.1 , pp. 31-36
    • Parr, D.M.1    Connell, G.E.2    Kells, D.I.3    Hofmann, T.4
  • 44
    • 0017736374 scopus 로고
    • Fragments produced by digestion of human immunoglobulin G subclasses with pepsin in urea.
    • Parr, D. M. (1977) Fragments produced by digestion of human immunoglobulin G subclasses with pepsin in urea. Bio -ehem. J. 165 (2), 303–308.
    • (1977) Bio -ehem. J. , vol.165 , Issue.2 , pp. 303-308
    • Parr, D.M.1
  • 48
    • 0023583876 scopus 로고
    • Monoclonal antibody drug conjugates for site-directed cancer chemotherapy: Preclinical pharmacology and toxicology studies.
    • Johnson, I. S., Spearman, M. E., Todd, G. C., Zimmerman, J. L., and Bumol, T. F. (1987) Monoclonal antibody drug conjugates for site-directed cancer chemotherapy: Preclinical pharmacology and toxicology studies. Cancer Treat. Rev. 14 (3–4), 193–196.
    • (1987) Cancer Treat. Rev. , vol.14 , Issue.3-4 , pp. 193-196
    • Johnson, I.S.1    Spearman, M.E.2    Todd, G.C.3    Zimmerman, J.L.4    Bumol, T.F.5
  • 49
    • 0023219736 scopus 로고
    • Antitumor xenograft activity with a conjugate of a Vinca derivative and the squamous carcinoma-reactive monoclonal antibody PF1/D.
    • Johnson, D. A. and Laguzza, B. C. (1987) Antitumor xenograft activity with a conjugate of a Vinca derivative and the squamous carcinoma-reactive monoclonal antibody PF1/D. Cancer Res. 47 (12), 3118–3122.
    • (1987) Cancer Res. , vol.47 , Issue.12 , pp. 3118-3122
    • Johnson, D.A.1    Laguzza, B.C.2
  • 51
    • 0002576771 scopus 로고
    • An overview of therapy with immunotoxins containing ricin or its A Chain
    • Blakey, D. C. and Thorpe, D. C. (1983) An overview of therapy with immunotoxins containing ricin or its A Chain. Antibody, Immunoconjugates, Radiopharm. 1, 1–16.
    • (1983) Antibody, Immunoconjugates, Radiopharm. , vol.1 , pp. 1-16
    • Blakey, D.C.1    Thorpe, D.C.2
  • 54
    • 0022446137 scopus 로고
    • Effects of therapy with T101 ricin A-chain immunotoxin in two leukemia patients
    • Laurent, G., Pris, J., and Farcet, J-P. (1986) Effects of therapy with T101 ricin A-chain immunotoxin in two leukemia patients. Blood 67, 1680–1687.
    • (1986) Blood , vol.67 , pp. 1680-1687
    • Laurent, G.1    Pris, J.2    Farcet, J.-P.3
  • 55
    • 0023131765 scopus 로고
    • Therapy of patients with malignant melanoma using a monoclonal antimela-noma antibody ricin A chain immunotoxin
    • Spitler, L., del Rio, M., Khentigan, A., et al. (1987) Therapy of patients with malignant melanoma using a monoclonal antimela-noma antibody ricin A chain immunotoxin. Cancer Res. 47, 1717–1723.
    • (1987) Cancer Res. , vol.47 , pp. 1717-1723
    • Spitler, L.1    del Rio, M.2    Khentigan, A.3
  • 56
    • 0023554984 scopus 로고
    • New coupling agents for the synthesis of immunotoxins containing a hindered disulfide bond with improved stability in vivo.
    • Thorpe, P. E., Wallace, P. M., Knowles, P. P., Reif, M. G., Brown, A. N., Watson, G. J., Knyba, R. E., Wawrzynczak, E. J. and Blakey, D. C. (1987) New coupling agents for the synthesis of immunotoxins containing a hindered disulfide bond with improved stability in vivo. Cancer Res. 47 (22), 5924–5931.
    • (1987) Cancer Res. , vol.47 , Issue.22 , pp. 5924-5931
    • Thorpe, P.E.1    Wallace, P.M.2    Knowles, P.P.3    Reif, M.G.4    Brown, A.N.5    Watson, G.J.6    Knyba, R.E.7    Wawrzynczak, E.J.8    Blakey, D.C.9
  • 57
    • 0022970025 scopus 로고
    • Effect of linkage variation of pharmacokinetics of ricin A chain-antibody conjugates in normal rats.
    • Worrell, N. R., Cumber, A. J., Parnell, G. D., Mirza, A., Forrester, J. A., and Ross, W. C. (1986) Effect of linkage variation of pharmacokinetics of ricin A chain-antibody conjugates in normal rats. Anticancer Drug Des. 1 (3), 179–188.
    • (1986) Anticancer Drug Des. , vol.1 , Issue.3 , pp. 179-188
    • Worrell, N.R.1    Cumber, A.J.2    Parnell, G.D.3    Mirza, A.4    Forrester, J.A.5    Ross, W.C.6
  • 61
    • 0023156998 scopus 로고
    • Clinical parameters related to optimal tumor localization of indium-lll-labeled mouse antimelanoma monoclonal antibody ZME-018
    • Murray, J. L., Rosenblum, M. G., Lamki, L., et al. (1987) Clinical parameters related to optimal tumor localization of indium-lll-labeled mouse antimelanoma monoclonal antibody ZME-018. J. Nucl. Med. 28, 25–33.
    • (1987) J. Nucl. Med. , vol.28 , pp. 25-33
    • Murray, J.L.1    Rosenblum, M.G.2    Lamki, L.3
  • 62
    • 0023516782 scopus 로고
    • Antibody-guided irradiation of advanced ovarian cancer with intraperi-toneally administered radiolabeled monoclonal antibodies
    • Epenetos, A. A., Munro, A. J., Stewart, S. et al. (1987) Antibody-guided irradiation of advanced ovarian cancer with intraperi-toneally administered radiolabeled monoclonal antibodies. J. Clin. Oncol. 5, 1890–1899.
    • (1987) J. Clin. Oncol. , vol.5 , pp. 1890-1899
    • Epenetos, A.A.1    Munro, A.J.2    Stewart, S.3
  • 64
    • 0024477746 scopus 로고
    • Effect of mass of 111ln-benzyl-EDTA monoclonal antibody on hepatic uptake and processing in mice.
    • Adams, G. P., DeNardo, S. J., Deshpands, S. V., DeNardo, G. L., Meares, C. F., McCall, M. J., and Epstein, A. L. (1989) Effect of mass of 111ln-benzyl-EDTA monoclonal antibody on hepatic uptake and processing in mice. Cancer Res. 49 (7), 1707–1711.
    • (1989) Cancer Res. , vol.49 , Issue.7 , pp. 1707-1711
    • Adams, G.P.1    DeNardo, S.J.2    Deshpands, S.V.3    DeNardo, G.L.4    Meares, C.F.5    McCall, M.J.6    Epstein, A.L.7
  • 65
    • 84987453854 scopus 로고
    • Chelate radiochemistry: Cleavable linkers lead to altered levels of radioactivity in the liver
    • Meares, C. F., McCall, M. J., Desh-pande, S. V., DeNardo, S. J., and Goodwin, D. A. (1988) Chelate radiochemistry: Cleavable linkers lead to altered levels of radioactivity in the liver. Int. J. Cancer. 2, 99–102.
    • (1988) Int. J. Cancer. , vol.2 , pp. 99-102
    • Meares, C.F.1    McCall, M.J.2    Desh-pande, S.V.3    DeNardo, S.J.4    Goodwin, D.A.5
  • 67
    • 0022930742 scopus 로고
    • Metabolizable 111 In chelate conjugated anti-idiotype monoclonal antibody for radio-immunodetection of lymphoma in mice.
    • Haseman, M. K., Goodwin, D. A., Meares, C. F., Kaminski, M. S., Wensel, T. G., McCall, M. J., and Levy, R. (1986) Metabolizable 111 In chelate conjugated anti-idiotype monoclonal antibody for radio-immunodetection of lymphoma in mice. Eur. J. Nucl. Med. 12 (9), 455–460.
    • (1986) Eur. J. Nucl. Med. , vol.12 , Issue.9 , pp. 455-460
    • Haseman, M.K.1    Goodwin, D.A.2    Meares, C.F.3    Kaminski, M.S.4    Wensel, T.G.5    McCall, M.J.6    Levy, R.7
  • 68
    • 0022515047 scopus 로고
    • Chelating agents for the binding of metal ions to antibodies.
    • Meares, C. F. (1986) Chelating agents for the binding of metal ions to antibodies. Int. J. Radiat. Appl. Instrum. 13 (4), 311–318.
    • (1986) Int. J. Radiat. Appl. Instrum. , vol.13 , Issue.4 , pp. 311-318
    • Meares, C.F.1
  • 69
    • 0023010473 scopus 로고
    • Metal decomposition rates of 111 ln-DTPA and EDTA conjugates of monoclonal antibodies in vivo.
    • Goodwin, D. A., Meares, C. F., McTigue, M., McCall, M. J., and Chaovapong, W. (1986) Metal decomposition rates of 111 ln-DTPA and EDTA conjugates of monoclonal antibodies in vivo. Nucl. Med. Commun. 7 (11), 831–838.
    • (1986) Nucl. Med. Commun. , vol.7 , Issue.11 , pp. 831-838
    • Goodwin, D.A.1    Meares, C.F.2    McTigue, M.3    McCall, M.J.4    Chaovapong, W.5
  • 73
    • 0021512252 scopus 로고
    • Conjugation of antibodies with bifunctional chelating agents: Isothiocyanate and bromoacetamide reagents, methods of analysis, and subsequent addition of metal ions.
    • Meares, C. F., McCall, M. J., Rear-dan, D. T., Goodwin, D. A., Diamanti, C. I., and McTigue M. (1984) Conjugation of antibodies with bifunctional chelating agents: Isothiocyanate and bromoacetamide reagents, methods of analysis, and subsequent addition of metal ions. Anal. Biochem. 142 (1), 68–78.
    • (1984) Anal. Biochem. , vol.142 , Issue.1 , pp. 68-78
    • Meares, C.F.1    McCall, M.J.2    Rear-dan, D.T.3    Goodwin, D.A.4    Diamanti, C.I.5    McTigue, M.6
  • 74
    • 0019731879 scopus 로고
    • Technetium-99 m complexes of EDTA analogs: Studies of the radiochemistry and biodistribution.
    • Baker, R. J., Diamanti, C. I., Goodwin, D. A., and Meares, C. F. (1981) Technetium-99 m complexes of EDTA analogs: Studies of the radiochemistry and biodistribution. Int. J. Nucl. Med. Biol. 8 (2–3), 159–169.
    • (1981) Int. J. Nucl. Med. Biol. , vol.8 , Issue.2-3 , pp. 159-169
    • Baker, R.J.1    Diamanti, C.I.2    Goodwin, D.A.3    Meares, C.F.4
  • 77
    • 0023055743 scopus 로고
    • Preparation of protein conjugates via intermolecular hydrazone linkage.
    • King, T. P., Zhao, S. W., and Lam, T. (1986) Preparation of protein conjugates via intermolecular hydrazone linkage. Biochemistry 25 (19), 5774–5779.
    • (1986) Biochemistry , vol.25 , Issue.19 , pp. 5774-5779
    • King, T.P.1    Zhao, S.W.2    Lam, T.3
  • 78
    • 85022919420 scopus 로고
    • European Patent Number 0243929
    • Offord, R. and Rose, K. (1987) European Patent Number 0243929.
    • (1987)
    • Offord, R.1    Rose, K.2
  • 79
    • 0020123473 scopus 로고
    • The proteinase-catalysed synthesis of peptide hydrazides.
    • Jones, R. M. and Offord, R. E. (1982) The proteinase-catalysed synthesis of peptide hydrazides. Biochem. J. 203 (1), 125–129.
    • (1982) Biochem. J. , vol.203 , Issue.1 , pp. 125-129
    • Jones, R.M.1    Offord, R.E.2
  • 80
    • 0020536517 scopus 로고
    • Rapid preparation of human insulin and insulin analogues in high yield by enzyme-assisted semi-synthesis.
    • Rose, K., DePury, H., and Offord, R. E. (1983) Rapid preparation of human insulin and insulin analogues in high yield by enzyme-assisted semi-synthesis. Biochem. J. 211 (3), 671–676.
    • (1983) Biochem. J. , vol.211 , Issue.3 , pp. 671-676
    • Rose, K.1    DePury, H.2    Offord, R.E.3
  • 81
    • 0023796063 scopus 로고
    • Enzyme-assisted semisynthesis of polypeptide active esters and their use.
    • Rose, K., Herrero, C., Proud-foot, A. E., Offord, R. E., and Wallace, C. J. (1988) Enzyme-assisted semisynthesis of polypeptide active esters and their use. Biochem. J. 249 (1), 83–88.
    • (1988) Biochem. J. , vol.249 , Issue.1 , pp. 83-88
    • Rose, K.1    Herrero, C.2    Proud-foot, A.E.3    Offord, R.E.4    Wallace, C.J.5
  • 82
    • 85022954563 scopus 로고
    • Tumor localization of antitumor drug-antibody conjugates. Biodistribution of radiolabeled N,Ndimethyl adriamycin-B72.3 antibody conjugates with LS174T tumor xenografts in mice.
    • American Chemical Society Meeting, Dallas, Texas, Abstract No. 72, American Chemical Society, Washington, DC
    • Coughlin, D. J., King, H. D., DeVirgilio, M., Greway, G., and Alvarez, V. (1989) Tumor localization of antitumor drug-antibody conjugates. Biodistribution of radiolabeled N,Ndimethyl adriamycin-B72.3 antibody conjugates with LS174T tumor xenografts in mice. Abstracts of Papers American Chemical Society Meeting, Dallas, Texas, Abstract No. 72, American Chemical Society, Washington, DC.
    • (1989) Abstracts of Papers
    • Coughlin, D.J.1    King, H.D.2    DeVirgilio, M.3    Greway, G.4    Alvarez, V.5
  • 85
    • 0008003476 scopus 로고
    • Vinca alkaloids. XVII. Chemistry of catharanthine.
    • Gorman, M., Neuss, N., and Cone, N. J. (1965) Vinca alkaloids. XVII. Chemistry of catharanthine. J. Am. Chem. Soc. 87 (1), 93–99.
    • (1965) J. Am. Chem. Soc. , vol.87 , Issue.1 , pp. 93-99
    • Gorman, M.1    Neuss, N.2    Cone, N.J.3
  • 86
    • 0021330443 scopus 로고
    • Antigens associatd with a human lung adenocarcinoma defined by monoclonal antibodies.
    • Varki, N. M., Reisfeld, R. A., and Walker, L. E. (1984) Antigens associatd with a human lung adenocarcinoma defined by monoclonal antibodies. Cancer Res. 44 (2), 681–687.
    • (1984) Cancer Res. , vol.44 , Issue.2 , pp. 681-687
    • Varki, N.M.1    Reisfeld, R.A.2    Walker, L.E.3
  • 88
    • 0023730197 scopus 로고
    • Characterization of the human tumor and normal tissue reactivity of the KS1/ 4 monoclonal antibody.
    • Bumol, T. F., Marder, P., DeHerdt, S. V., Borowitz, M. J., and Apelgren, L. D. (1988) Characterization of the human tumor and normal tissue reactivity of the KS1/ 4 monoclonal antibody. Hybridoma 7 (4), 407–415.
    • (1988) Hybridoma , vol.7 , Issue.4 , pp. 407-415
    • Bumol, T.F.1    Marder, P.2    DeHerdt, S.V.3    Borowitz, M.J.4    Apelgren, L.D.5
  • 90
    • 0023087318 scopus 로고
    • Utilization of nude mice in research on human cancer-screening system of anticancer agent using human tumor xenografts in nude mice
    • Ueyama, Y. (1987) Utilization of nude mice in research on human cancer-screening system of anticancer agent using human tumor xenografts in nude mice. Prog. Clin. Biol. Res. 229, 287–310.
    • (1987) Prog. Clin. Biol. Res. , vol.229 , pp. 287-310
    • Ueyama, Y.1
  • 91
    • 0017314309 scopus 로고
    • Letter: Cancer xenografts in nude mice.
    • Garrett, A. J. and Franks, C. R. (1976) Letter: Cancer xenografts in nude mice. Lancet 1 (7952), 195.
    • (1976) Lancet , vol.1 , Issue.7952 , pp. 195
    • Garrett, A.J.1    Franks, C.R.2
  • 92
    • 0017297095 scopus 로고
    • Letter: Cancer xenografts in nuce mice.
    • Schmidt, M. and Good, R. A. (1976) Letter: Cancer xenografts in nuce mice. Lancet 1 (7949), 39.
    • (1976) Lancet , vol.1 , Issue.7949 , pp. 39
    • Schmidt, M.1    Good, R.A.2
  • 93
    • 0018899745 scopus 로고
    • Response to chemotherapy of human, malignant melanoma xenografts in athymic, nude mice.
    • Fodstad, O., Aass, N., and Pihl, A. (1980) Response to chemotherapy of human, malignant melanoma xenografts in athymic, nude mice. Int. J. Cancer 25 (4), 453–458.
    • (1980) Int. J. Cancer , vol.25 , Issue.4 , pp. 453-458
    • Fodstad, O.1    Aass, N.2    Pihl, A.3
  • 94
    • 0024117741 scopus 로고
    • Human tumor xenografts as model for drug testing.
    • Mattern, J., Bak, M., Hahn, E. W., and Volm, M. (1988) Human tumor xenografts as model for drug testing. Cancer Metastasis Reu. 7 (3), 263–284.
    • (1988) Cancer Metastasis Reu. , vol.7 , Issue.3 , pp. 263-284
    • Mattern, J.1    Bak, M.2    Hahn, E.W.3    Volm, M.4
  • 95
    • 0023231055 scopus 로고
    • Use of nude mouse xenografts as preclinical screens. Characterization of xenograft-derived melanoma cell lines.
    • Taetle, R., Jones, O. W., Honeysett, J. M., Abram-son, L., Bradshaw, C., and Reid, S. (1987) Use of nude mouse xenografts as preclinical screens. Characterization of xenograft-derived melanoma cell lines. Cancer 60 (8), 1836–1841.
    • (1987) Cancer , vol.60 , Issue.8 , pp. 1836-1841
    • Taetle, R.1    Jones, O.W.2    Honeysett, J.M.3    Abram-son, L.4    Bradshaw, C.5    Reid, S.6
  • 96
    • 0022515759 scopus 로고
    • Use of nude mouse xenografts as preclinical drug screens. Further studies on in vitro growth of xenograft tumor colony-forming cells.
    • Taetle, R., Honeysett, J. M., Rosen, F., and Shoemaker, R. (1986) Use of nude mouse xenografts as preclinical drug screens. Further studies on in vitro growth of xenograft tumor colony-forming cells. Cancer 58 (9), 1969–1978.
    • (1986) Cancer , vol.58 , Issue.9 , pp. 1969-1978
    • Taetle, R.1    Honeysett, J.M.2    Rosen, F.3    Shoemaker, R.4
  • 98
    • 0023583876 scopus 로고
    • Monoclonal antibody drug conjugates for site-directed cancer chemotherapy: Preclinical pharmacology and toxicology studies.
    • Johnson, I. S., Spearman, M. E., Todd, G. C., Zimmerman, J. L., and Bumol, T. F. (1987) Monoclonal antibody drug conjugates for site-directed cancer chemotherapy: Preclinical pharmacology and toxicology studies. Cancer Treat. Rev. 14 (3–4), 193–196.
    • (1987) Cancer Treat. Rev. , vol.14 , Issue.3-4 , pp. 193-196
    • Johnson, I.S.1    Spearman, M.E.2    Todd, G.C.3    Zimmerman, J.L.4    Bumol, T.F.5
  • 99
    • 85022944085 scopus 로고    scopus 로고
    • Tumor mass measurements did not vary over 30 % of the mean. Animals treated with KS1/4-DAVLB had tumor masses which were significantly different than control groups (P < O.001 via Student's t test analysis)
    • Bumol, T. F., personal communication. Tumor mass measurements did not vary over 30 % of the mean. Animals treated with KS1/4-DAVLB had tumor masses which were significantly different than control groups (P < O.001 via Student's t test analysis).
    • Personal communication
    • Bumol, T.F.1
  • 100
    • 0016648079 scopus 로고
    • 3H]vinblastine to embryonic chick brain tubulin and tubulin from sea urchin sperm tail outer doublet microtubules.
    • 3H]vinblastine to embryonic chick brain tubulin and tubulin from sea urchin sperm tail outer doublet microtubules. Biochemistry 14 (26), 5586–5592.
    • (1975) Biochemistry , vol.14 , Issue.26 , pp. 5586-5592
    • Wilson, L.1    Creswell, K.M.2    Chin, D.3
  • 101
    • 0016587150 scopus 로고
    • Microtubules as drug receptors: Pharmacological properties of microtubule protein
    • Wilson, L. (1975) Microtubules as drug receptors: Pharmacological properties of microtubule protein. Ann. N.Y. Acad. Sci. 253, 213–31.
    • (1975) Ann. N.Y. Acad. Sci. , vol.253 , pp. 213-231
    • Wilson, L.1
  • 102
    • 0017913111 scopus 로고
    • Differences in the binding properties of vinca alkaloids and colchicine to tubulin by varying protein sources and methodology.
    • Hans, F. O., Dickerson, R. M., Wilson, L., and Owellen, R. J. (1978) Differences in the binding properties of vinca alkaloids and colchicine to tubulin by varying protein sources and methodology. Biochem. Pharmacol. 27 (1), 71–76.
    • (1978) Biochem. Pharmacol. , vol.27 , Issue.1 , pp. 71-76
    • Hans, F.O.1    Dickerson, R.M.2    Wilson, L.3    Owellen, R.J.4
  • 103
    • 0023248720 scopus 로고
    • Disposition of the monoclonal antibody-vinca alkaloid conjugate KS1/4-DAVLB (LY256787) and free 4-desacetylvinblastine in tumor-bearing nude mice.
    • Spearman, M. E., Goodwin, R. M., Apelgren, L. D., and Bumol, T. F. (1987) Disposition of the monoclonal antibody-vinca alkaloid conjugate KS1/4-DAVLB (LY256787) and free 4-desacetylvinblastine in tumor-bearing nude mice. J. Pharmacol. Exp. Ther. 241 (2), 695–703.
    • (1987) J. Pharmacol. Exp. Ther. , vol.241 , Issue.2 , pp. 695-703
    • Spearman, M.E.1    Goodwin, R.M.2    Apelgren, L.D.3    Bumol, T.F.4
  • 107
    • 0024561482 scopus 로고
    • New antitumor monoclonal antibody-vinca conjugates LY203625 and related compounds: Design, preparation, and representative in vivo activity.
    • Laguzza, B. C., Nichols, C. L., Briggs, S. L., Cullinan, G. J., Johnson, D. A., Starling, J. J., Baker, A. L., Bumol, T. F., Corvalan, J. R. (1989) New antitumor monoclonal antibody-vinca conjugates LY203625 and related compounds: Design, preparation, and representative in vivo activity. J. Med. Chem. 32 (3), 548–555.
    • (1989) J. Med. Chem. , vol.32 , Issue.3 , pp. 548-555
    • Laguzza, B.C.1    Nichols, C.L.2    Briggs, S.L.3    Cullinan, G.J.4    Johnson, D.A.5    Starling, J.J.6    Baker, A.L.7    Bumol, T.F.8    Corvalan, J.R.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.