Pharmacokinetics of methotrexate administered by intramuscular and subcutaneous injections in patients with rheumatoid arthritis

Arthritis & Rheumatism

Volumn 33, Issue 1, 1990, Pages 91-94

  Brooks, Paul J ^a,b,c   Spruill, William J ^a,b   Parish, Roy C ^a,b   Birchmore, Daniel A ^a,b  

^a University of Georgia College of Pharmacy ^*  (United States)

^b UNIVERSITY OF GEORGIA   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METHOTREXATE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; FEMALE; HUMAN; INTRAMUSCULAR DRUG ADMINISTRATION; MALE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SUBCUTANEOUS DRUG ADMINISTRATION;

AGED; ARTHRITIS, RHEUMATOID; HUMAN; INJECTIONS, INTRAMUSCULAR; INJECTIONS, SUBCUTANEOUS; METHOTREXATE; MIDDLE AGE; OSMOLAR CONCENTRATION; STATISTICS; SUPPORT, NON-U.S. GOV'T;

EID: 0025190680     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.1780330112     Document Type: Article

References (12)

1. The current status of methotrexate use in rheumatic diseases.
2. Immunosuppressive and antiinflammatory properties of cyclophosphamide, azathioprine and methotrexate.
3. The use of methotrexate in rheumatoid arthritis.
4. An approach to the use of immunosup‐pressive drugs in nonmalignant diseases.
5. Comparison of serum concentrations of methotrexate after various routes of administration.
6. Pharmacokinetics of small doses of methotrexate in patients with psoriasis.
7. Weekly intravenous methotrexate in the treatment of rheumatoid arthritis.
8. Methotrexate bioavailability after oral and intramuscular administration in children.
9. Methotrexate: bioavailability and pharmacokinetics.
10. Pharmacokinetics of subcutaneous methotrexate.