Synthesis and Pharmacological Evaluation of a Series of Dibenzo[a,b]cycloalkenimines as N-Methyl-D-aspartate Antagonists

Journal of Medicinal Chemistry

Volumn 33, Issue 2, 1990, Pages 789-808

  Thompson, Wayne J ^a   Anderson, Paul S ^a   Britcher, Susan F ^a   Lyle, Terry A ^a   Thies, J Eric ^a   Magill, Catherine A ^a   Varga, Sandor L ^a   Schwering, John E ^a   Lyle, Paulette A ^a   Christy, Marcia E ^a   Evans, Ben E ^a   Colton, C Dylion ^a   Springer, James P ^a   Hirshfield, Jordan M ^a   Ball, Richard G ^a   Amato, Joseph S ^a   Wong, Erik H F ^a   Kemp, John A ^a   Tricklebank, Mark D ^a   Singh, Lakhbir ^a   Oles, Ryszard ^a   Priestly, Tony ^a   Marshall, George R ^a   Knight, Antony R ^a   Middlemiss, Derek N ^a   Woodruff, Geoffrey N ^a   Iversen, Leslie L ^a   Holloway, M Katharine ^b   Larsen, Robert D ^b   more..

^a MERCK RESEARCH LABORATORIES   (United States)

^b NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DIBENZO[A,D]CYCLOHEPTANE DERIVATIVE; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN; CONVULSION; DRUG ANTAGONISM; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; INTRAVENOUS DRUG ADMINISTRATION; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION;

EID: 0025189893     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00164a052     Document Type: Article

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