Effects of various inducers on diethylstilbestrol metabolism, drug-metabolizing enzyme activities and the aromatic hydrocarbon (Ah) receptor in male syrian golden hamster liver

Journal of Steroid Biochemistry

Volumn 35, Issue 2, 1990, Pages 201-204

  Blaich, Günter ^a   Göttlicher, Martin ^a   Cikryt, Peter ^a   Metzler, Manfred ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME B5; CYTOCHROME P450; DIETHYLSTILBESTROL;

ANIMAL CELL; ARTICLE; DRUG METABOLISM; HAMSTER; LIVER CARCINOGENESIS; LIVER MICROSOME; MALE; NONHUMAN; PRIORITY JOURNAL;

ANIMAL; BENZOFLAVONES; BIOTRANSFORMATION; CARCINOGENS; CYTOCHROME B5; CYTOCHROME P-450 ENZYME SYSTEM; DIETHYLSTILBESTROL; DRUG INTERACTIONS; ENZYME INDUCTION; HAMSTERS; MALE; MESOCRICETUS; METHYLCHOLANTHRENE; MICROSOMES, LIVER; PHENOBARBITAL; RECEPTORS, ARYL HYDROCARBON; RECEPTORS, DRUG; SUPPORT, NON-U.S. GOV'T; TETRACHLORODIBENZODIOXIN;

ANIMALIA; CRICETINAE; MESOCRICETUS AURATUS;

EID: 0025189604     PISSN: 00224731     EISSN: None     Source Type: Journal    
DOI: 10.1016/0022-4731(90)90275-W     Document Type: Article

References (13)

1. High incidence of hepatocellular carcinomas after synthetic estrogen administration in Syrian golden hamsters fed a-naphthoflavone. A new tumor model
2. Estrogen-induced tumors of the kidney. I. Incidence of renal tumors in intact and gonadectomized male golden hamsters treated with diethylstilbestrol
3. The P450 gene superfamily: recommended nomenclature
4. Quantitative evaluation of the promotion by 2,3,7,8-tetrachlorodibenzo-p-dioxin of hepatocarcino-genesis from diethylnitrosamine
5. Metabolism of diethylstilbestrol in hamster hepatocytes
6. Effect of pretreatment of male Syrian golden hamsters with 7,8-benzoflavone and with diethylstilbestrol on P450 isoenzyme activities and on microsomal diethylstilbestrol metabolism
7. Rapid vertical tube rotor gradient assay for binding of 2378-tetrachloro-dibenzo-p-dioxin to the Ah receptor
8. The affinity of carcinogenic aromatic amides to the rat hepatic aromatic hydrocarbon (Ah) receptor in vitro and in vivo
9. Induction of different isozymes of cytochrome P450 and of microsomal epoxide hydrase in rat liver by 2-acetyl-aminofluorene and structurally related compounds
10. Co-induction of cytochrome P450 isozymes in rat liver by 2,4,5,2',4',5'-hexachlorobiphenyl or 3-methoxy-4-aminoazobenzene
11. a-Naphthoflavone antagonism of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced murine lymphocyte ethoxyresorufin-O-deethylase activity and immunosuppression
12. Elevated binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 3-methyl-cholanthrene to the Ah receptor in hepatic cytosols from phenobarbital-treated rats and mice
13. Induction of the aromatic hydrocarbon receptor by trans-4-acetylaminostilbene in rat liver. Comparison with other aromatic amines