Cultured endothelial cells maintain their L-arginine level despite the continuous release of EDRF

European Journal of Pharmacology

Volumn 182, Issue 3, 1990, Pages 573-576

  Mitchell, Jane A ^a   Hecker, Markus ^a   Ånggård, Erik E ^a   Vane, John R ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

(Bioassay); (HPLC); EDRF (endothelium derived relaxing factor); Endothelial cells; L Arginine

Indexed keywords

ARGININE; ENDOTHELIUM DERIVED RELAXING FACTOR;

ANIMAL CELL; AORTA; ARTICLE; CATTLE; CELL CULTURE; CELL LEVEL; ENDOTHELIUM CELL; NONHUMAN; PRIORITY JOURNAL;

AMINO ACIDS; ANIMAL; ARGININE; CATTLE; CELLS, CULTURED; CHROMATOGRAPHY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENDOTHELIUM, VASCULAR; NITRIC OXIDE; SUPEROXIDE DISMUTASE; SUPPORT, NON-U.S. GOV'T;

EID: 0025182892     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(90)90058-E     Document Type: Article

References (11)

1. Receptor mediated release of endothelium-derived relaxing factor and prostacyclin from bovine endothelial cells is coupled
2. 2 from BAEC by infusions of ADP, bradykinin, arachidonic acid, L-arginine and alkaline buffer
3. L-Arginine causes whereas L-argininosuccininc acid inhibits endothelium-dependent vascular smooth muscle relaxation
4. G-monomethyl-L-arginine to L-citrulline and subsequently to L-arginine
5. Maximum activities of some key enzymes of glycolysis, glutaminolysis, Krebs cycle and fatty acid utilization in bovine pulmonary endothelial cells
6. The generation of L-arginine in endothelial cells is linked to the release of endothelium-derived relaxing factor
7. Vascular endothelial cells synthesize nitric oxide from L-arginine
8. Role of endothelium-derived nitric oxide in the regulation of blood pressure
9. Arginine is the physiological precursor of endothelium-derived relaxing factor
10. Vascular activity of polycations and basic amino acids: L-arginine does not specifically elicit endothelium-dependent relaxation
11. The use of isolated organs for detecting active substances in the circulating blood