Catalytic asymmetric alkylation of aldehydes by diethylzinc in the presence of N-iso-propylephedrine; dependence of enantioselectzvity on Et2Zn:RCHO

Tetrahedron Letters

Volumn 31, Issue 36, 1990, Pages 5185-5188

  Chaloner, Penny A ^a   Langadianou, Eugenia ^a  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE;

ARTICLE; DRUG STABILITY; DRUG SYNTHESIS; NONHUMAN; PRIORITY JOURNAL; REACTION ANALYSIS;

EID: 0025180449     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)97838-9     Document Type: Article

References (14)

1. Asymmetric synthesis of alcohols with two chiral centres from a racemic aldehyde by the selective addition of dialkylzinc reagents using (1S,2R)-(?)-N,N-dibutylnorephedrine and (S)-(+)-diphenyl-(1-methylpyrrolidin-2-yl)methanol as chiral catalysts
2. Enantioselective addition of diethylzinc to aldehydes catalyzed by polymer-supported chiral amino alcohols. Evidence for a two zinc species mechanism
3. Asymmetric Synthesis
4. Asymmetric synthesis via axially dissymmetric molecules. A binaphthol-modified complex aluminum hydride reagent possessing extremely high ability of chiral recognition
5. Catalytic enantioselective conjugate addition of dialkylzincs to .ALPHA.,.BETA.-unsaturated ketones using nickel bromide-N,N-dibutylnorephedrine.