Chlorinated biphenyls induce cytochrome P450IA2 and uroporphyrin accumulation in cultures of mouse hepatocytes

Archives of Biochemistry and Biophysics

Volumn 281, Issue 2, 1990, Pages 225-232

  Sinclair, Peter R ^a,b   Bement, William J ^a   Lambrecht, Richard W ^a   Gorman, Nadia ^a,b   Sinclair, Jacqueline F ^a,b  

^a VA MEDICAL CENTER   (United States)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; UROPORPHYRIN;

ANIMAL CELL; ARTICLE; CELL CULTURE; LIVER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

AMINOLEVULINIC ACID; ANIMAL; CELLS, CULTURED; COMPARATIVE STUDY; CULTURE MEDIA; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; IRON; ISOENZYMES; LIVER; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; POLYCHLORINATED BIPHENYLS; PORPHYRINS; RATS; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; TIME FACTORS; UROPORPHYRINS;

ANIMALIA; MAMMALIA;

EID: 0025172709     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/0003-9861(90)90436-3     Document Type: Article

References (45)

1. Dexamethasone-mediated regulation of 3-methylcholanthrene-induced cytochrome P-450d mRNA accumulation in primary rat hepatocyte cultures.
2. Induction of two immunochemically related rat liver cytochrome P-450 isozymes, cytochromes P-450c and P-450d, by structurally diverse xenobiotics.
3. Effects of polychlorinated biphenyls on cytochrome P450 induction in the chick embryo hepatocyte culture