5′-O-Phosphonomethyl-2′3′-Dideoxynucleosides: Synthesis and Anti-HIV Activity

Journal of Medicinal Chemistry

Volumn 33, Issue 9, 1990, Pages 2481-2487

  Jie, Liu ^a   Aerschot, Arthur Van ^a   Balzarini, Jan ^a   Janssen, Gerard ^a   Busson, Roger ^a   Clercq, Erik De ^a   Hoogmartens, Jos ^b   Herdewijn, Piet ^c  

^a Laboratories of Pharmaceutical Chemistry and Antiviral Chemotherapy ^*  (Belgium)

^b and Institute for Pharmaceutical Sciences ^*  (India)

^c UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

2',3' DIDEOXYNUCLEOSIDE; 3' AZIDO 3' DEOXY 5' O (PHOSPHONOMETHYL)THYMIDINE; 3' DEOXY 3' FLUORO 5' O (PHOSPHONOMETHYL)THYMIDINE; 3' FLUOROTHYMIDINE; 5' O (TRIPHOSPHOMETHYL) 3' DEOXY 3' FLUOROTHYMIDINE; RNA DIRECTED DNA POLYMERASE; UNCLASSIFIED DRUG; ZIDOVUDINE;

ARTICLE; CELL CULTURE; CYTOPATHOGENIC EFFECT; DRUG SCREENING; DRUG SYNTHESIS; HUMAN IMMUNODEFICIENCY VIRUS; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL;

ANTIVIRAL AGENTS; CHEMISTRY; DIDEOXYNUCLEOSIDES; HIV-1; HUMAN; ORGANOPHOSPHORUS COMPOUNDS; REVERSE TRANSCRIPTASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T;

EID: 0025167912     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00171a023     Document Type: Article

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