Renin Inhibitors Containing Isosteric Replacements of the Amide Bond Connecting the P3and P2Sites

Journal of Medicinal Chemistry

Volumn 33, Issue 2, 1990, Pages 838-845

  Kaltenbronn, J S ^a   Hudspeth, J P ^a   Lunney, E A ^a   Michniewicz, B M ^a   Nicolaides, E D ^a   Repine, J T ^a   Roark, W H ^a   Stier, M A ^a   Tinney, F J ^a   Woo, P K W ^a   Essenburg, A D ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RENIN INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DRUG STABILITY; DRUG SYNTHESIS; ENZYME INHIBITION; HYPERTENSION; MONKEY; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANTIHYPERTENSIVE AGENTS; CHEMISTRY; CHYMOTRYPSIN; HUMAN; HYDROLYSIS; IN VITRO; PROTEASE INHIBITORS; RENIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0025165020     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00164a058     Document Type: Article

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