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Volumn 29, Issue 9, 1990, Pages 977-991

The Directed Synthesis of Biaryl Compounds: Modern Concepts and Strategies

Author keywords

Arenes; Asymmetric synthesis; Biaryls; Synthetic methods

Indexed keywords

GOSSYPOL; STEGANONE;

EID: 0025164652     PISSN: 05700833     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.199009771     Document Type: Review
Times cited : (679)

References (190)
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    • For exceptions see e.g. [24]
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    • Schlüsselbausteine der Naturstoff-Biosynthese und ihre Bedeutung für Chemie und Medizin
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    • Nickel and palladium complex catalyzed cross-coupling reactions of organometallic reagents with organic halides
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    • Palladium-katalysierte Kupplungsreaktionen organischer Elektrophile mit Organozinn-Verbindungen
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    • In the case of very electron‐poor aromatic compounds (such as oxazoline‐substituted quinolines) the electrophilic coupling partner does not require a nucleofugal group
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    • In another example, an unnatural but biologically more active aza‐analogous dibenzocyclooctadiene, the thermodynamic equilibrium even lies at only 1:40
  • 183
    • 84990145541 scopus 로고
    • A further advantage of this process is that apart from 42 and 43 hydroxymethyl compounds of type 41 and lactones of type 40 are found as natural products in the same plants and can thus be included synthetically without additional effort:, Planta med. 56
    • (1990)
    • Bringmann, G.1    Rübenacker, M.2    Jansen, J.R.3    Gender, T.4    Aké Assi, L.5
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    • In contrast, precomplexation of the alkali metal cation of basic hydride transfer reagents at nitrogen and attack of the anionic hydride part of the reagent from the same side (i.e. from above) should lead to the other lactolate diastercomer (not shown in Scheme 27), which bears the hydrogen in β‐position; this isomer should react in an analogous manner to give 45b.
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    • See for example the non‐stereoselective synthesis of a (probably not separable) mixture of all four possible stereoisomeric ancistrocladisines [113].


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.