The ventral pallidum plays a role in mediating cocaine and heroin self-administration in the rat

Brain Research

Volumn 508, Issue 1, 1990, Pages 20-29

  Hubner, Carol B ^a   Koob, George F ^a  

^a SCRIPPS CLINIC   (United States)

Author keywords

Cocaine; Heroin; Ibotenic acid; Progressive ratio schedule; Rat; Self administration; Ventral pallidum

Indexed keywords

COCAINE; DIAMORPHINE; IBOTENIC ACID; NALOXONE;

ANIMAL EXPERIMENT; ARTICLE; GLOBUS PALLIDUS; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; SELF STIMULATION;

ANIMAL; BEHAVIOR, ANIMAL; COCAINE; GLOBUS PALLIDUS; HEROIN; MALE; RATS; RATS, INBRED STRAINS; REINFORCEMENT SCHEDULE; SELF ADMINISTRATION; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0025162171     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(90)91112-T     Document Type: Article

References (36)

1. Cocaine reinforced progressive ratio performance in the rhesus monkey
2. Intracranial self-administration of morphine into the ventral tegmental area in rats
3. Effect of haloperidol on (+)-amphetamine self-administration
4. Blockade of cocaine reinforcement in rats with the dopamine receptor blocker pimozide but not with the noradrenergic blockers phentolamine or phenoxybenzamine
5. Heroin and cocaine intravenous self-administration in rats: mediation by separate neural systems
6. Changes in morphine self-administration and morphine dependence after lesions of the caudate nucleus in rats
7. Intracranial self-administration of methionine enkephalin into the nucleus accumbens
8. Nalorphine-induced changes in morphine self-administration in rhesus monkey
9. Comparison of progressive-ratio performance maintained by cocaine, methylphenidate and secobarbital
10. Progressive-ratio performance maintained by drug infusions: comparison of cocaine, diethylpropion, chlorphentermine, and fenfluramine
11. Progressive ratio and fixed ratio schedules of cocaine-maintained responding in baboons
12. Progressive ratio as a measure of reward strength
13. Effects of increment size and reinforcer volume on progressive ratio performance
14. Progressive-ratio performance in the rhesus monkey maintained by opiate infusions
15. Effects of opiate antagonists and their quaternary derivatives on heroin self-administration in the rat
16. Positive reinforcement properties of drugs: search for neural substrates
17. Destruction of dopaminergic nerve terminals in the nucleus accumbens: effect on d-amphetamine self-administration
18. Evidence that an accumbens to subpallidal GABA-ergic projection contributes to locomotor activity
19. Neural projections from the nucleus accumbens to globus pallidus, substantia innominata, and lateral preoptic-lateral hypothalamic area: an anatomical and electrophysiological investigation in the rat
20. Destruction of the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats
21. Cocaine-reinforced behavior in rats: effects of reinforcement magnitude and fixed ratio size
22. On the role of ascending catecholamine systems in intravenous self-administration of cocaine
23. Extinction and recovery of cocaine self-administration following 6-hydroxydopamine lesions of the nucleus accumbens
24. Disruption of cocaine self-administration following 6-hydroxydopamine lesions of the ventral tegmental area in rats
25. Atypical neuroleptics increase self-administration of cocaine: an evaluation of a behavioral screen for antipsychotic activity
26. Increased motivation to self-administer apomorphine following 6-hydroxydopamine lesions of the nucleus accumbens
27. Electrolytic lesions of the substantia innominata and lateral preoptic area attenuate the ‘suppressive’ locomotor response to apomorphine resulting from denervation of the nucleus accumbens
28. Substantia innominata: critical link in the behavioral expression of mesolimbic dopamine stimulation in the rat
29. Separate neural substrates of the locomotor-activity properties of amphetamine, heroin, caffeine, and corticotropin releasing factor (CRF) in the rat
30. Effects of intracerebroventricular administration of methylnaloxone on heroin self-administration in the rat
31. Blockade of nucleus accumbens opiate receptors attenuates intravenous heroin reward in the rat
32. Changes in morphine self-administration in rats induced by prostaglandin E and naloxone
33. The efferent projections of the nucleus accumbens in the rat
34. Disruption of cocaine and heroin self-administration following kainic acid lesions of the nucleus accumbens