Serologic responses to Pneumocystis carinii antigens in health and disease

Journal of Infectious Diseases

Volumn 161, Issue 2, 1990, Pages 296-306

  Peglow, Sheree L ^a,b,c   Smulian, A George ^a,b,c   Linke, Michael J ^a,b,c   Pogue, Cheryl L ^a,b,c   Nurre, Stephen ^a,b,c   Crisler, Jane ^a,b,c   Phair, John ^a,b,c   Gold, Jonathan W M ^a,b,c   Armstrong, Donald ^a,b,c   Walzer, Peter D ^a,b,c  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; PARASITE ANTIGEN;

ANTIBODY RESPONSE; ARTICLE; HOST PARASITE INTERACTION; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; IMMUNOBLOTTING; NONHUMAN; PNEUMOCYSTIS CARINII; PNEUMOCYSTOSIS; PRIORITY JOURNAL; PROTOZOON;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ADULT; ANTIBODIES, FUNGAL; ANTIGENS, FUNGAL; CASE REPORT; CHILD, PRESCHOOL; COMPARATIVE STUDY; HUMAN; IMMUNE TOLERANCE; IMMUNOBLOTTING; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INFANT; IOWA; OPPORTUNISTIC INFECTIONS; PNEUMOCYSTIS CARINII; PNEUMONIA, PNEUMOCYSTIS CARINII; PREVALENCE; RECURRENCE; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0025159270     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/161.2.296     Document Type: Article

References (67)

1. Walzer P.D., Kim C.K., Cushion M.T., Pneumocystis carinii. In: Walzer P.D., Genta R.M., eds. Parasitic infections in the compromised host. New York: Marcel Dekker, 1989:83–178.
2. Meuwissen J.H.E.Th., Thuber I., Leeuwenberg A.D.E.M., Beckers P.J.A., Sieben M., Parasitologic and serologic observations of infection with Pneumocystis in humans. J Infect Dis 1977;136:43–49.
3. Pifer L.L., Hughes W.T., Stagno S., Woods D., Pneumocystis carinii infection: evidence for high prevalence in normal and immunosuppressed children. Pediatrics 1978;61:35–41.
4. Kagan I.G., Norman L.N., Serology of pneumocystosis. NCI Monogr 1976;43:121–125.
5. Shepherd V.B., Jameson B., Knowles G.K., Pneumocystis cariniipneumonitis: a serological study. J Clin Pathol 1979;32:773–777.
6. Gerrard M.P., Eden O.B., Jameson B., Craft A.W., Serological study of Pneumocystis carinii infection in the absence of immunosuppression. Arch Dis Child 1987;62:177–179.
7. Tanabe K., Furuta T., Ueda K., Tanaka H., Shimada K., Serological observations of Pneumocystis carinii infection in humans. J Clin Microbiol 1985;22:1058–1060.
8. Girón J.A., Martinez S., Walzer P.D., Should inpatients with Pneumocystis carinii be isolated [letter]? Lancet 1982;2:46.
9. Hofmann B., Ødum N., Platz P., Ryder L.P., Svejgaard A., Nielsen P.B., Holten-Andersen W., Gerstoft J., Nielsen J.O., Mojon M., Humoral responses to Pneumocystis carinii in patients with acquired immunodeficiency syndrome and in immunocompromised homosexual men. J Infect Dis 1985;152:838–840.
10. Hofmann B., Nielsen P.B., Ødum N., Gerstoft J., Platz P., Ryder L.P., Poulsen A.G., Mathiesen L., Dickmeiss E., Norrild B., Andersen H.K., Westergaard B.F., Nielsen C.M., Holten-Andersen W., Mojon M., Nielsen J.O., Svejgaard A., Humoral and cellular responses to Pneumocystis carinii, CMV, and herpes simplex in patients with AIDS and in controls. Scand J Infect Dis 1988;20:389–394.
11. Maddison S.E., Hayes G.V., Slemenda S.B., Norman L.G., Ivey M.H., Detection of specific antibody by enzyme–linked immunosorbent assay and antigenernia by counterimmunoelectrophoresis in humans infected with Pneumocystis carinii. J Clin Microbiol 1982;15:1036–1043.
12. Maddison S.E., Walls K.W., Haverkos H.W., Juranek D.D., Evaluation of serologic tests for Pneumocystis carinii antibody and antigenemia in patients with acquired immunodeficiency syndrome. Diagn Microbiol Infect Dis 1984;2:69–75.
13. Radulescu S., Niculeseu D., Petrasincu D., Lazar L., Butnariu J., Baciu M.C., Buttucea L.V., Maneseu V.II, Evaluation of enzyme linked immunosorbent assay as a serodiagnostic tool–clinical and epidemiological aspects of pneumocystosis in young infants. Arch Roum Pathol Exp Microbiol1986;45:117–128.
14. Pifer L.L.W., Niell H.B., Langdon S.B., Baltz S., Clark S.T., Edwards C.C., Woods D.R., Evidence for depressed humoral immunity to Pneumocystis cariniiin homosexual males, commercial plasma donors, and patients with acquired immunodeficiency syndrome. J Clin Microbiol 1987; 25:991–995.
15. Matthews P.C., Immunoblotting in the serodiagnosis of infectious diseases. Serodiagn Immunother 1987;1:165–167.
16. Calhoun D.L., Osir E.O., Dugger K.O., Galgiani J.N., Law J.H., Humoral antibody responses to specific antigens of Coccidioides immitis. J Infect Dis 1986;154:265–272.
17. Potasman I., Araujo F.G., Thulliez P., Desmonts G., Remington J.S., Ioxoplasma gondii antigens recognized by sequential samples of serum obtained from congenitally infected infants. J Clin Microbiol 1987; 25:1926–1931.
18. Weiss L.M., Udem S.A., Tanowitz H., Wittner M., Western blot analysis of the antibody response of patients with AIDS and toxoplasma encephalitis: antigenic diversity among Ioxoplasma strains. J Infect Dis 1988;157:7–13.
19. Kirchhoff L.V., Gam A.A., da Gusmao R., Goldsmith R.S., Rezende J.M., Rassi A., Increased specificity of serodiagnosis of Chagas’ disease by detection of antibody to the 72– and 90–kilodalton glycoproteins of Trypanosoma cruzi. J Infect Dis 1987;155:561–564.
20. Slemenda S.B., Maddison S.E., Jong E.C., Moore D.O., Diagnosis of paragonimiasis by immunoblot. Am J Trop Med Hyg 1988;39:469–471.
21. Grodzicki R.L., Steere A.C., Comparison of immunoblotting and indirect enzyme–linked immunosorbent assay using different antigen preparations for diagnosing early Lyme disease. J Infect Dis 1988;157: 790–797.
22. Dobson S.R.M., Taber L.H., Baughn R.E., Recognition of Treponema pallidum antigens by IgM and IgG antibodies to congenitally infected newborns and their mothers. J Infect Dis 1988;157:903–910.
23. Gold D., Ashley R., Handsfield H.H., Verdon M., Leach L., Mills J., Drew L., Corey L., Immunoblot analysis of the humoral immune response in primary cytomegalovirus infection. J Infect Dis 1988;157:319–326.
24. Dubey L., Steinberg S.P., LaRussa P., Oh P., Gershon A.A., Western blot analysis of antibody to varicella–zoster virus. J Infect Dis 1988; 157:882–888.
25. Kahlon J., Whitley R.J., Antibody response of the newborn after herpes simplex virus infection. J Infect Dis 1988;158:925–933.
26. Gigliotti F., Stokes D.C., Cheatham A.B., Davis O.S., Hughes W.T., Development of murine monoclonal antibodies to Pneumocystis carinii. J Infect Dis 1986;154:315–322.
27. Gigliotti F., Ballou L.R., Hughes W.T., Mosley B.D., Purification and initial characterization of a ferret Pneumocystis carinii surface antigen. J Infect Dis 1988;158:848–854.
28. Gigliotti F., Hughes W.T., Passive immunoprophylaxis with specific monoclonal antibody confers partial protection against Pneumocystis carinii pneumonitis in animal models. J Clin Invest 1988;81:1666–1668.
29. Graves D.C., McNabb S.J.N., Ivey M.H., Worley M.A., Development and characterization of monoclonal antibodies to Pneumocystis carinii. Infect Immun 1986;51:125–133.
30. Graves D.C., McNabb S.J.N., Whorley M.A., Downs T.O., Ivey M.H., Analysis of rat Pneumocystis carinii antigens recognized by human and rat antibodies by using Western immunoblotting. Infect Immun 1986; 54:96–103.
31. Kovacs J.A., Halpern J.L., Swan J.C., Moss J., Parrillo J.E., Masur H., Identification of antigens and antibodies specific for Pneumocystis carinii. J Immunol 1988;140:2023–2031.
32. Kovacs J.A., Halpern J.L., Lundgren B., Swan J.E., Parrillo J.E., Masur H., Monoclonal antibodies to Pneumocystis carinii: identification of specific antigens and characterization of antigenic differences between rat and human isolates. J Infect Dis 1989;159:60–70.
33. Lee C.H., Bolinger C.D., Bartlett M.S., Kohler R.B., Wilde CE III, Smith J.W., Production of monoclonal antibody against Pneumocystis carinii by using a hybrid of rat spleen and mouse myeloma cells. J Clin Microbiol 1986;23:505–508.
34. Linder E., Lundin L., Vorma H., Detection of Pneumocystis carinii in lung–derived samples using monoclonal antibodies to an 82 kDa parasite component. J Immunol Methods 1987;98:57–62.
35. Walzer P.O., Linke M.J., A comparison of the antigenic characteristics of rat and human Pneumocystis carinii by immunoblotting. J Immunol 1987;138:2257–2265.
36. Walzer P.O., Stanforth D., Linke M.J., Cushion M.T., Pneumocystis carinii: immunoblotting and immunofluorescent analyses of serum antibodies during experimental rat infection and recovery. Exp Parasitol 1987;63:319–328.
37. Linke M.J., Cushion M.T., Walzer P.D., Properties of the major antigens of rat and human Pneumocystis carinii. Infect Immun 1989;57: 1547–1555.
38. Walzer P.O., Kim C.K., Linke M.J., Pogue C.L., Huerkamp M.J., Chrisp C.E., Lerro A.V., Wixson S.K., Hall E., Shultz L.D., Outbreaks of Pneumocystis carinii pneumonia in colonies of immunodeficient mice. Infect Immun 1989;57:62–70.
39. Tanabe K., Takasaki S., Watanabe J.I., Kobata A., Egawa K., Nakamura Y., Glycoproteins composed of major surface immunodeterminants of Pneumocystis carinii, Infect Immun 1989;57;1363–1368.
40. Radding J.A., Armstrong M.Y.K., Ullu E., Richards F.E., Identification and isolation of a major cell surface glycoprotein of Pneumocystis carinii. Infect Immun 1989;57:2149–2157.
41. Cushion M.T., Ruffolo J.J., Linke M.J., Walzer P.D., Pneumocystis carinii: growth variables and estimates in the A549 and WI–38 VA13 human cell lines. Exp Parasitol 1985;60:43–54.
42. Kim C.K., Foy J.M., Cushion M.T., Stanforth D., Linke M.J., Hendrix H.L., Walzer P.D., Comparison of histologic and quantitative techniques in evaluationof therapy for experimental Pneumocystis carinii pneumonia. Antimicrob Agents Chemother 1987;31:197–201.
43. Laemmli U.K., Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680–685.
44. Towbin H., Staehelin T., Gordon J., Electrophoretic transfer proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 1979;76:4350–4354.
45. Walzer P.O., Rutledge M.E., Humoral immunity in experimental Pneumocystis carinii infection. I. Serum and bronchial lavage fluid antibody responses in rats. J Lab Clin Med 1981;97:820–833.
46. Soulez B., Dei-Cas E., Camus D., The rabbit as experimental host of Pneumocystis carinii. Ann Parasitol Hum Comp 1988;63:5–15.
47. Edman J.C., Kovacs J.A., Masur H., Santi D.V., Elwood H.J., Sogin M.L., Ribosomal RNA sequence shows Pneumocystis carinii to be a member of the fungi. Nature 1988;334:519–522.
48. Watanabe J.I., Hori H., Tanabe K., Nakamura Y., Phylogenetic association of Pneumocystis cariniiwith the ‘Rhizopoda/Myxomycota/Zygomycota group’ indicated by comparison of 5S ribosomal RNA sequences. Mol Biochem Parasitol 1989;32:163–168.
49. Stringer S.L., Stringer J.R., Blase M.A., Walzer P.D., Cushion M.T., Pneumocystis carinii: sequence from ribosomal RNA implies a close relationship with fungi. Exp Parasitol 1989;68:450–461.
50. Walzer P.D., Rutledge M.E., Serum antibody responses to Pneumocystis carinii among different strains of normal and athymic mice. Infect Immun 1982;35:620–626.
51. Furuta T., Fujiwara K., Yamanouchi K., Ueda K., Detection of antibodies to Pneumocystis carinii by enzyme–linked immunosorbent assay in experimentally infected mice. J Parasitol 1985;71:522–523.
52. McNabb S.J.N., Graves D.C., Kosanke S.D., Moyer M.J., Ivey M.H., Pneumocystiscarinii antigen detection in rat serum and lung lavage. J Clin Microbiol 1988;26:1763–1771.
53. Rankin J.A., Walzer P.D., Dwyer J.M., Schrader C.E., Enriquez R.E., Merrill W.W., Immunologic alterations in bronchoalveolar lavage fluid in the acquired immunodeficiency syndrome (AIDS). Am Rev Respir Dis 1983;128:189–194.
54. Lane H.C., Masur H., Edgar L.C., Whalen G., Rook A.H., Fauci A.S., Abnormalities of B–cell activation and immunoregulation in patients with the acquired immunodeficiency syndrome. N Engl J Med 1983; 309:453–458.
55. Carne C.A., Weller I.V.D., Waite J., Briggs M., Pearce F., Adler M.W., Tedder R.S., Impaired responsiveness of homosexual men with HIV antibodies to plasma derived hepatitis B vaccine. Br Med J 1987;294:866–868.
56. Janoff E.N., Douglas J.M. Jr., Gabriel M., Blaser M.J., Davidson A.J., Cohn D.L., Judson F.N., Class–specific antibody response to pneumococcal capsular polysaccharidesin men infectedwith human immunodeficiency virus type 1. J Infect Dis 1988;158:983–990.
57. Borkowsky W., Steele C.J., Grubman S., Moore T., La Russa P., Krasinski K., Antibody responses to bacterial toxoids in children infected with human immunodeficiency virus. J Pediatr 1987;110:563–566.
58. Janoff E.N., Smith P.D., Blaser M.J., Acute antibody responses to Giardia lamblia are depressed in patients with AIDS. J Infect Dis 1988; 157:798–804.
59. Ungar B.L.P., Soave R., Fayer R., Nash T.E. Enzyme immunoassay detection of immunoglobulin M and G antibodies to Cryptosporidium in immunocompetentand immunocompromised persons. J Infect Dis 1986;153:570–578.
60. Wong B., Gold J.W.M., Brown A.E., Lange M., Fried R., Grieco M., Mildvan D., Giron J., Tapper M.L., Lerner C.W., Armstrong D., Centralnervous– system toxoplasmosis in homosexual menand parenteraldrug abusers. Ann Intern Med 1984;100:36–42.
61. Luft B.J., Brooks R.G., Conley F.K., McCabe R.E., Remington J.S., Toxoplasmic encephalitis in patients with acquired immune deficiency syndrome. JAMA 1984;252:913–917.
62. Roberts C.J., Coccidioidomycosis in acquired immune deficiency syndrome. Depressed humoralas well as cellular immunity. AmJ Med 1984;76:734–736.
63. Dylewski J., Chou S., Merigan T.C., Absenceof detectableIgM antibody during cytomegalovirus disease in patientswithAIDS[letter]. N Engl J Med 1983;309:493.
64. Hagler D.N., Deepe G.S., Pogue C.L., Walzer P.D., Blastogenic responses to Pneumocystis carinii among patients with human immunodeficiency virus (HIV) infection. Clin Exp Immunol 1988;74:7–13.
65. Masur H., Jones T.C., The interaction in vitro of Pneumocystis carinii with macrophages and L–cells. J Exp Med 1978;147:157–170.
66. Walzer P.D., Schultz M.G., Western K.A., Robbins J.B., Pneumocystis carinii pneumonia and primary immune deficiency diseases of infancyand childhood. J Pediatr 1973;82:416–422.
67. Rao C.P., Gelfand E.W., Pneumocystis cariniipneumonitis in patients with hypogammaglobulinemia and intact Tcell immunity. J Pediatr 1983; 103:410–412.