Synthesis and Structure-Activity Relationships of New 9-N-Alkyl Derivatives of 9 (S)-Erythromycylamine

Journal of Medicinal Chemistry

Volumn 33, Issue 11, 1990, Pages 3086-3094

  Kirst, Herbert A ^a   Wind, Julie A ^a   Leeds, James P ^a   Willard, Kevin E ^a   Debono, Manuel ^a   Bonjouklian, Rosanne ^a   Greene, James M ^a   Sullivan, Kevin A ^a   Paschal, Jonathan W ^a   Deeter, Jack B ^a   Jones, Noel D ^a   Ott, John L ^a   Felty Duckworth, Anna M ^a   Counter, Fred T ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

9 N PROPYLERYTHROMYCYLAMINE; ERYTHROMYCIN; ERYTHROMYCYLAMINE; ERYTHROMYCYLAMINE DERIVATIVE; LY 281389; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL INFECTION; BLOOD LEVEL; CELL CULTURE; DRUG SCREENING; DRUG SYNTHESIS; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION; SUBCUTANEOUS DRUG ADMINISTRATION; TISSUE LEVEL;

ALKYLATION; ANIMAL; BACTERIAL INFECTIONS; CHEMISTRY; COMPARATIVE STUDY; ERYTHROMYCIN; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MOLECULAR STRUCTURE; RATS; STAPHYLOCOCCAL INFECTIONS; STREPTOCOCCAL INFECTIONS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0025155117     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00173a028     Document Type: Article

References (14)

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