Synthesis and structure-activity of 4(5)-(2,2-diphenylethyl)imidazoles as new α2-adrenoreceptor antagonists

European Journal of Medicinal Chemistry

Volumn 25, Issue 7, 1990, Pages 557-568

  Cordi, AA ^a   Snyers, MP ^b   Giraud Mangin, D ^b   Van der Maesen, C ^b   Van Hoeck, JP ^b   Beuze, S ^b   Ellens, E ^b   Napora, F ^b   Gillet, CL ^b   Gorissen, H ^b   Calderon, P ^b   Remacle, MD ^b   Janssens de Varebeke, P ^b   Van Dorsser, W ^b   Roba, J ^b  

^a MONSANTO COMPANY   (United States)

^b Product Safety   (Belgium)

Author keywords

imidazole derivatives; norepinephrine uptake inhibitor; 2 adrenoreceptor antagonist

Indexed keywords

4 (2,2 DIPHENYLETHYL)IMIDAZOLE; 4 (2,2 DIPHENYLETHYL)IMIDAZOLE DERIVATIVE; ALPHA 2 ADRENERGIC RECEPTOR; CLONIDINE; IDAZOXAN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; DRUG ANTAGONISM; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SYNTHESIS; GUINEA PIG; MOUSE; NONHUMAN; NORADRENALIN UPTAKE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; SEROTONIN UPTAKE; STRUCTURE ACTIVITY RELATION;

EID: 0025148333     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/0223-5234(90)90180-B     Document Type: Article

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