Repeat unit sequence variation in minisatellites: A novel source of DNA polymorphism for studying variation and mutation by single molecule analysis

Cell

Volumn 60, Issue 3, 1990, Pages 473-485

  Jeffreys, Alec J ^a   Neumann, Rita ^a   Wilson, Victoria ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

REPETITIVE DNA; SATELLITE DNA;

ALLELE; ARTICLE; DNA STRUCTURE; HUMAN; HUMAN CELL; MUTATION RATE; PRIORITY JOURNAL;

ALLELES; BASE SEQUENCE; CHROMOSOME DELETION; DNA, SATELLITE; GENETIC TECHNIQUES; HAPLOTYPES; HUMAN; MALE; MOLECULAR SEQUENCE DATA; MUTATION; OLIGONUCLEOTIDE PROBES; POLYMORPHISM (GENETICS); REPETITIVE SEQUENCES, NUCLEIC ACID; RESTRICTION MAPPING; SPERMATOZOA; SUPPORT, NON-U.S. GOV'T; VARIATION (GENETICS);

EID: 0025141652     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(90)90598-9     Document Type: Article

References (34)

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4. Evolution of animal mitochondrial DNA
5. Hypervariable minisatellite regions are sites for crossing-over at meiosis in man
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17. Application of multilocus and single locus minisatellite DNA probes in forensic medicine
18. Characterization of a highly unstable mouse minisatellite locus: evidence for somatic mutation during early development
19. DNA fingerprinting on trial
20. Amplification and analysis of DNA sequences in single human sperm and diploid cells
21. Characterization of a human ‘midisatellite’ sequence
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23. Analysis of a 1963-bp polymorphic region flanking the human insulin gene
24. Linkage, physical mapping, and DNA sequence analysis of pseudoautosomal loci on the human X and Y chromosomes
25. Clustering of hypervariable minisatellites in the proterminal region of human autosomes
26. Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase
27. Linkage disequilibrium in human ribosomal genes: implications for multigene family evolution
28. Evolution of repeated DNA sequences by unequal crossover
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31. Unequal crossingover between homologous chromosomes is not the major mechanism involved in the generation of new alleles at VNTR loci
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33. Characterization of a panel of highly variable minisatellites cloned from human DNA