Molecular biology of non-Hodgkin's lymphomas

Seminars in Oncology

Volumn 17, Issue 1, 1990, Pages 30-42

  McKeithan, Timothy W ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN; HUMAN CELL; MOLECULAR BIOLOGY; NONHODGKIN LYMPHOMA; ONCOGENE; PRIORITY JOURNAL; REVIEW;

EXONS; HUMAN; LYMPHOMA, NON-HODGKIN; ONCOGENES; TRANSLOCATION (GENETICS);

EID: 0025139877     PISSN: 00937754     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (66)

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3. Activation of cellular oncogenes in hemopoietic cells by chromosome translocation
4. The molecular genetics of human non-Hodgkin's lymphoma
5. Translocation, breakage and truncated transcripts of c-myc oncogene in murine plasmacytomas
6. 6;7 chromosomal translocation in spontaneously arising rat immunocytomas: Evidence for c-myc breakpoint clustering and correlation between isotypic expression and the c-myc target
7. Identification and nucleotide sequence of a human locus homologous to the v-myc oncogene of avian myelocytomatosis virus MC29
8. Novel promoter upstream of the human c-myc gene and regulation of c-myc expression in B-cell lymphomas
9. A non-AUG translational initiation in c-myc exon 1 generates an N-terminally distinct protein whose synthesis is disrupted in Burkitt's lymphoma
10. The leucine zipper: A hypothetical structure common to a new class of DNA binding proteins
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13. 1
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15. Aberrant c-myc RNAs of Burkitt's lymphoma cells have longer halflives
16. Truncation of exon 1 from the c-myc gene results in prolonged c-myc mRNA stability
17. c-myc oncogene protein synthesis is independent of the cell cycle in human and avian cells
18. The first exon of the c-myc proto-oncogene contains a novel positive control element
19. A negative transcriptional control element located upstream of the murine c-myc gene
20. A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells
21. Sequence requirements for premature termination of transcription in the human c-myc gene
22. Avian leukemia viruses: Interaction with their target cells in vivo and in vitro
23. Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis
24. Significance of chromosome 8 breakpoint location in Burkitt's lymphoma: correlation with geographic origin and association with Epstein-Barr Virus
25. Different regions of the immunoglobulin heavy-chain locus are involved in chromosomal translocations in distinct pathogenetic forms of Burkitt lymphoma
26. Chromosomal breakpoints and structural alterations of the c-myc locus differ in endemic and sporadic forms of Burkitt lymphoma
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28. The c-myc oncogene perturbs B lymphocyte development in Eμ-myc transgenic mice
29. Pathogenesis of Burkitt lymphoma: Expression of an activated c-myc oncogene causes the tumorigenic conversion of EBV-infected human B lymphoblasts
30. Translocated c-myc oncogene of Burkitt lymphoma is transcribed in plasma cells and repressed in lymphoblastoid cells
31. Repression of rearranged μ gene and translocated c-myc in mouse 3T3 cell x Burkitt lymphoma cell hybrids
32. Coexpression of translocated and normal c-myc oncogenes in hybrids between Daudi and lymphoblastoid cells
33. The t(8;14) breakpoint of the EW 36 undifferentiated lymphoma cell line lies 5′ of myc in a region prone to involvement in endemic Burkitt's lymphoma
34. Strong transcriptional activation of translocated c-myc genes occurs without a strong nearby enhancer or promoter
35. Deletion of a B-cell-specific enhancer affects transfected, but not endogenous, immunoglobulin heavy-chain gene expression
36. Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching
37. Clustered somatic mutations in and around first exon on non-rearranged c-myc in Burkitt lymphoma with t(8;22)
38. Mutations in the first exon are associated with altered transcription of c-myc in Burkitt lymphoma
39. myc oncogene involved in a t(8;22) chromosome translocation is not altered in its putative regulatory regions
40. Sequence analysis of the MYC oncogene involved in the t(8;14)(q24;q11) chromosome translocation in a human leukemia T-cell line indicates that putative regulatory regions are not altered
41. Intragenic pausing and antisense transcription within the murine c-myc locus
42. Chromosomal abnormalities in lymphoid tumours: mechanisms and role in tumour pathogenesis
43. The t(8;14) chromosomal translocation occurring in B-cell malignancies results from mistakes in V-D-J joining
44. Somatic generation of antibody diversity
45. Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation
46. H on chromosome 14 and near a transcriptional unit on 18
47. Bcl-2 and other genomic alterations in the prognosis of large-cell lymphoma
48. Alternative promoters and exons, somatic mutation and deregulation of the Bcl-2—Ig fusion gene in lymphoma
49. Regulation of bcl-2 proto-oncogene expression during normal human lymphocyte proliferation
50. Expression in non-Hodgkin's lymphoma of the bcl-2 protein associated with the t(14;18) chromosomal translocation
51. Recent progress on the human bcl-2 gene involved in follicular lymphoma: Characterization of the protein products
52. Oncogenic potential of bcl-2 demonstrated by gene transfer
53. Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
54. bcl-2—immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation
55. Molecular cloning of the chromosomal breakpoint of B-cell lymphomas and leukemias with the t(11;14) translocation
56. Gene encoding the α chain of the T-cell receptor is moved immediately downstream of c-myc in a chromosomal 8;14 translocation in a cell line from a human T-cell leukemia
57. Molecular mechanisms of a t(8;14)(q24;q11) translocation juxtaposing c-myc and TcR-α genes in a T-cell leukaemia: Involvement of a Vα internal heptamer
58. Molecular cloning of the breakpoint junction of a human chromosomal 8;14 translocation involving the T-cell receptor α-chain gene and sequences on the 3′ side of MYC
59. The mechanism of chromosome 14 inversion in a human T cell lymphoma
60. Common mechanism of chromosome inversion in B- and T-cell tumors: Relevance to lymphoid development
61. Human T-cell tumours containing chromosome 14 inversion or translocation with breakpoints proximal to immunoglobulin joining regions at 14q32
62. Molecular analysis of a t(7;14)(q35;q32) chromosome translocation in a T cell leukemia of a patient with ataxia telangiectasia
63. The mechanism of chromosomal translocation t(11;14) involving the T-cell receptor Cδ locus on human chromosome 14q11 and a transcribed region of chromosome 11p15
64. Analysis of DNA surrounding the breakpoints of chromosomal translocations involving the β T cell receptor gene in human lymphoblastic neoplasms
65. Chromosomal translocation involving the β T cell receptor gene in acute leukemia