Mucoid Pseudomonas aeruginosa in cystic fibrosis: mutations in the muc loci affect transcription of the algR and algD genes in response to environmental stimuli

Molecular Microbiology

Volumn 4, Issue 2, 1990, Pages 189-196

  Deretic, V ^a   Govan, J R W ^b   Konyecsni, W M ^a   Martin, D W ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARCA; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA;

ALGINIC ACID;

ARTICLE; CASE REPORT; CYSTIC FIBROSIS; DNA TRANSCRIPTION; HUMAN; MUTATION; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA;

ALGINATES; CARBOHYDRATE DEHYDROGENASES; CYSTIC FIBROSIS; GENE EXPRESSION REGULATION, BACTERIAL; GLYCOSAMINOGLYCANS; HUMAN; MUTATION; NITROGEN; POLYSACCHARIDES, BACTERIAL; PROMOTER REGIONS (GENETICS); PSEUDOMONAS AERUGINOSA; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; TRANSCRIPTION FACTORS;

EID: 0025136898     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.1990.tb00586.x     Document Type: Article

References (39)

1. High osmolarity is a signal for enhanced algD transcription in mucoid and nonmucoid Pseudomonas aeruginosa strains
2. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein‐dye binding
3. Characterization of a gene, glnL, the product of which is involved in the regulation of nitrogen utilization in Escherichia coli.
4. Cloning of genes controlling alginate biosynthesis from mucoid cystic fibrosis isolate of Pseudomonas aeruginosa.
5. Gene amplification induces mucoid phenotype in rec‐2 Pseudomonas aeruginosa exposed to kanamycin
6. Alginate biosynthesis: a model system for gene regulation and function in Pseudomonas.
7. Gene algD coding for GDPmannose dehydrogenase is transcriptionally activated in mucoid Pseudomonas aeruginosa.
8. Pseudomonas aeruginosa infection in cystic fibrosis: nucleotide sequence and transcriptional regulation of the algD gene
9. The algR gene, which regulates mucoidy in Pseudomonas aeruginosa, belongs to a class of environmentally responsive genes
10. Common denominators of promoter control in Pseudomonas and other bacteria
11. Control of mucoidy in Pseudomonas aeruginosa: transcriptional regulation of algR and identification of the second regulatory gene, algQ.
12. Replication of an origin‐containing derivative of plasmid RK2 dependent on a plasmid function provided in trans.
13. Use of a gene replacement cosmid vector for cloning alginate conversion genes from mucoid and nonmucoid Pseudomonas aeruginosa strains; algS controls expression of algT.
14. Alginate synthesis in mucoid Pseudomonas aeruginosa: a chromosomal locus involved in control
15. Synthesis, regulation and function of bacterial alginates
16. Construction and characterization of algB mutants of Pseudomonas aeruginosa: role of algB in high‐level production of alginate
17. Alginate biosynthesis and other unusual characteristics associated with the pathogenesis of Pseudomonas aeruginosa in cystic fibrosis
18. Localization of Bacillus subtilis SacU (Hy) mutations to two linked genes with similarities to the conserved procaryotic family of two‐component signalling systems
19. Phosphorylation of three proteins in the signaling pathway of bacterial chemotaxis
20. A physiological role for DNA supercoiling in the osmotic regulation of gene expression in S. typhimurium and E. coli
21. Differentiation of arcA, arcB, and cpxA mutant phenotypes of Escherichia coli by sex pilus formation and enzyme regulation
22. EnvZ, a transmembrane environmental sensor of Escherichia coli K‐12, is phosphorylated in vitro.
23. Nitrogen control in Pseudomonas aeruginosa: a role for glutamine in the regulation of the synthesis of NADP‐dependent glutamate dehydrogenase, urease, and histidase
24. Protein kinase and phosphoprotein phosphatase activities of nitrogen regulatory proteins NtrB and NtrC of enteric bacteria: roles of the conserved amino‐terminal domain of NtrC
25. A new modification of the carbazole reaction: application to heteropolysaccharides
26. Broad‐host‐range plasmid and M13 bacteriophage‐derived vectors for promoter analysis in Escherichia coli and Pseudomonas aeruginosa.
27. Regulation of carbon and nitrogen utilization
28. Transfer of a chromosomal locus responsible for mucoid colony morphology in Pseudomonas aeruginosa isolated from cystic fibrosis patients to P. aeruginosa PAO
29. Molecular Cloning. A Laboratory Manual
30. Interaction between two proteins in osmoregulatory expression of ompF and ompC genes in Escherichia coli: a novel ompR mutation suppresses pleitropic defect caused by an envZ mutation
31. Coordinate regulation and sensory transduction in the control of bacterial virulence
32. II, regulates the transcription of the glnALG operon in Escherichia coli.
33. Crosstalk between bacterial chemotaxis signal transduction proteins and regulators of transcription of the Ntr regulon: evidence that nitrogen assimilation and chemotaxis are controlled by a common phosphotransfer mechanism
34. Recalibration of the Pseudomonas aeruginosa strain PAO chromosomal map in time units using high‐frequency‐of‐recombination donors
35. Conserved domains in bacterial regulatory proteins that respond to environmental stimuli
36. The pUC plasmids, an m13mp7‐derived system for insertion mutagenesis and sequencing with synthetic universal primers
37. Control of bacterial alkaline phosphatase synthesis and variation in Escherichia coli K‐12 phoR mutant by adenyl cyclase, the cyclic AMP receptor binding protein, and the phoM operon
38. I) of Escherichia coli.