The three carboxy-terminal amino acids of human interleukin-6 are essential for its biological activity

FEBS Letters

Volumn 273, Issue 1-2, 1990, Pages 95-98

  Krüttgen, Alex ^a   Rose John, Stefan ^a   Dufhues, Gabi ^a   Bender, Sven ^a   Lütticken, Claudia ^a   Freyer, Peter ^a   Heinrich, Peter C ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

Acute phase protein induction; Biological activity; Carboxy terminus; Deletion mutant; Interleukin 6; PCR

Indexed keywords

ACUTE PHASE PROTEIN; INTERLEUKIN 6; RADIOISOTOPE;

ARTICLE; HUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMAL; BASE SEQUENCE; CELL DIVISION; CELL LINE; CHROMOSOME DELETION; FIBRINOGEN; HUMAN; INTERLEUKIN-6; KINETICS; MICE; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDE PROBES; PLASMACYTOMA; SUPPORT, NON-U.S. GOV'T;

EID: 0025134958     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-5793(90)81059-W     Document Type: Article

References (15)

1. Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor