Prevention of myocardial enzyme release by ranolazine in a primate model of ischaemia with reperfusion

British Journal of Pharmacology

Volumn 99, Issue 1, 1990, Pages 5-6

  Allely, M C ^a   Alps, B J ^a  

^a Syntex Research Europe   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CREATINE KINASE; LACTATE DEHYDROGENASE; RANOLAZINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ENZYME RELEASE; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HEART PROTECTION; INTRAVENOUS DRUG ADMINISTRATION; MALE; MONKEY; NONHUMAN; PRIORITY JOURNAL; REPERFUSION;

EID: 0025134189     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1990.tb14641.x     Document Type: Article

References (9)

1. ALLELY 1988 The effects of the novel antianginal agent ranolazine (i.d.) in a canine model of transient myocardial ischaemia Br. J. Pharmacol 93 246P
2. ALLELY 1987 10.1042/bst0151057 The effects of the novel anti-anginal agent RS 43285 on [lactic acid], [K+] and pH in a canine model of transient myocardial ischaemia Biochem. Soc. Trans 15 1057
3. FISHER 1960 The Design of Experiments 44
4. GALEN 1975 10.1001/jama.1975.03250020019017 Diagnosis of acute myocardial infarction: relative efficiency of serum enzymes and isoenzyme measurements J. Am. Med. Assoc 232 145
5. GANOTE 1976 Oxygen-induced enzyme release after irreversible myocardial injury Am. J. Pathol 84 327
6. HEARSE 1973 10.1016/0022-2828(73)90030-8 Abrupt reoxygenation of the anoxic potassium-arrested perfused rat heart: a study of myocardial enzyme release J. Mol. Cell. Cardiol 5 395
7. MANDERS 1975 Altered relationship between creatine phosphokinase release and infarct size with reperfusion in conscious dogs [abstr] Circulation Suppl 52 II
8. NORRIS 1979 Infarct Size Quantification, Present and Future 363
9. YASMINEH 1977 10.1161/01.CIR.55.5.733 Serial serum creatinine phosphokinase MB isoenzyme activity after myocardial infarction: studies in the baboon and man Circulation 55 733