Synthesis and Serotonin Binding Site Studies of Some Conformationally Restricted Indolylethylamine Analogues Based on 2-Amino-3-(3'-indolyl)bicyclo[2.2.2]octane

Journal of Medicinal Chemistry

Volumn 33, Issue 1, 1990, Pages 386-394

  Schlecht, M F ^a   Burkhart, Joseph P ^a   Tsarouhtsis, D ^a   Lipovac, M N ^b   Debler, Shujaath ^b  

^a UNIVERSITY OF SALERNO   (Italy)

^b NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (3 INDOLYL) 3 (1 PIPERIDYL)BICYCLO[2.2.2]OCTAN 5 ONE; 2 (31INDOLYL) 3 (1 PYRROLIDINYL)BICYCLO[2.2.2]OCT 5 ENE; 2 AMINO 3 (3 INDOLYL)BICYCLO[2.2.2]OCTANE DERIVATIVE; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; KETANSERIN; SEROTONIN 1A RECEPTOR; SEROTONIN 2 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMAL; BICYCLO COMPOUNDS; BINDING SITES; BRIDGED COMPOUNDS; CELL MEMBRANE; CEREBRAL CORTEX; CHEMISTRY; CHEMISTRY, PHYSICAL; COMPARATIVE STUDY; INDOLES; KETANSERIN; MICE; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; RECEPTORS, SEROTONIN; SEROTONIN; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, U.S. GOV'T, P.H.S.; TETRAHYDRONAPHTHALENES; THERMODYNAMICS;

EID: 0025117704     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00163a062     Document Type: Article

References (4)

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