Kupffer Cell Blockade Increases Mortality During Intra-abdominal Sepsis Despite Improving Systemic Immunity

Archives of Surgery

Volumn 125, Issue 1, 1990, Pages 36-41

  Callery, Mark P ^a,b   Kamei, Takafumi ^a   Flye, M Wayne ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b American Liver Foundation Postdoctoral Research Fellow ^*

Author keywords

[No Author keywords available]

Indexed keywords

GADOLINIUM CHLORIDE;

ANIMAL EXPERIMENT; CELLULAR IMMUNITY; CONFERENCE PAPER; FATALITY; LIVER CELL; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; SEPSIS;

ABDOMEN; ANIMAL; BACTERIAL INFECTIONS; FEMALE; GADOLINIUM; HYPERSENSITIVITY, DELAYED; IMMUNOSUPPRESSION; INTERLEUKIN-1; KUPFFER CELLS; MACROPHAGE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, INBRED STRAINS; PHAGOCYTOSIS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0025117647     PISSN: 00040010     EISSN: 15383644     Source Type: Journal    
DOI: 10.1001/archsurg.1990.01410130038005     Document Type: Article

References (34)

1. Saba TM. Physiology and pathophysiology ofthe reticuloendothelial system. Arch Intern Med. 1970;126:1031-1052.
2. Mathison JC, Ulevitch R. The clearance, tissue distribution and cellular localization of intravenously injected lipopolysaccharide in rabbits. J Immunol. 1979;123:2133-2243.
3. Ruiter DJ, van der Meulen J, Brower A, et al. Uptake by liver cells of endotoxin following its intravenous injection. Lab Invest. 1981;45:38-45.
4. Marshall JC, Lee C, Meakins JL, Michel RP, Christou NV. Kupffer cell modulation ofthe systemic immune response. Arch Surg. 1987;122:191-196.
5. Marshall JC, Rode H, Christou NV, Meakins JL. In vivo activation of Kupffer cells by endotoxin causes suppression of nonspecific, but not specific, systemic immunity. Surg Forum. 1988;39:111-113.
6. MacLean LD, Meakins JL, Taguchi K, Duignan JP, Dhillon KS, Gordon J. Host resistance in sepsis and trauma. Ann Surg. 1975;182:207-217.
7. Rogoff TM, Lipsky PE. Role of the Kupffer cells in local and systemic immune responses. Gastroenterology. 1981;80:854-860.
8. Lautenschlager I. Characteristics of strongly la-positive cells in rat liver. Scand J Immunol. 1984;20:333-338.
9. Rogoff TM, Lipsky PE. Antigen presentation by isolated guinea pig Kupffer cells. J Immunol. 1980;124:1740-1744.
10. Richman LK, Klingenstein RJ, Richman JA, Strober W, Berzofsky JA. The murine Kupffer cell, I: characterization of the cell serving accessor}' function in antigen-specific T-cell proliferation. J Immunol. 1979;123:2602-2609.
11. Decker K. Eicosanoids, signal molecules of liver cells. Semin Liver Dis. 1985;5:175-190.
12. McCuskey RS, McCuskey PA, Urbaschek R, Urbaschek B. Kupffer cell function in host defense. Rev Infect Dis. 1987;9(suppl 5):S616-S619.
13. Decker T, Lohmann-Matthes ML, Karck TJ, Peters T, Decker K. Comparative study of cytotoxicity, tumor necrosis factor, and prostaglandin release after stimulation of rat Kupffer cells, murine Kupffer cells, and murine inflammatory liver macrophages. J Leukocyte Biol. 1989;45:139-146.
14. Border JR. Hypothesis: sepsis, multiple system organ failure, and the macrophage. Arch Surg. 1988;123:285-286.
15. Husztik E, Lazar G, Parducz A. Electron microscopic study of Kupffer-cell phagocytosis blockade induced by gadolinium chloride. Br J Exp Pathol. 1980;61:624-630.
16. Callery MP, Kamei T, Flye MW. Kupffer cell blockade inhibits induction of tolerance by the portal venous route. Transplantation. 1989;47:1092-1094.
17. Titus RG, Chiller JM. A simple and effective method to assess murine delayed-type hypersensitivity to proteins. J Immunol Methods. 1981;45:65-73.
18. Kaye J, Janeway C A. Induction of receptors for interleukin 2 requires T-cell Ag la receptor cross-linking and interleukin 1. Lymphokine Res. 1984;3:175-182.
19. Baker CC, Chaudry IH, Gaines HO, Baue AE. Evaluation of factors affecting mortality rate after sepsis in a murine cecal ligation and puncture model. Surgery. 1983;94:331-335.
20. Fry DE, Pearlstein L, Fulton RL, Polk HC. Multiple system organ failure: the role of uncontrolled infection. Arch Surg. 1980;115:136-140.
21. Unanue ER. Antigen-presenting function ofthe macrophage. Annu Rev Immunol. 1984;2:395-428.
22. Dinarello CA. Biology of interleukin 1. FASEB J. 1988;2:108-115.
23. Renz H, Gong JH, Schmidt A, Nain M, Gemsa D. Release of tumor necrosis factor from macrophages: enhancement and suppression are dose-dependently regulated by prostaglandin E2 and cyclic nueleotides. J Immunol. 1988;141:2388-2393.
24. Nathan CF. Secretory products of macrophages. J Clin Invest. 1987;79:319-326.
25. Wang BS, Heacock EH, Wu AVO, Mannick JA. Generation of suppressor cells in mice after surgical trauma. J Clin Invest. 1980;66:200-209.
26. Faist E, Mewes A, Strasser T, et al. Alteration of monocyte function following major injury. Arch Surg. 1988;123:287a-292.
27. West MA, Keller GA, Hyland BJ, Cerra FB, Simmons RL. Hepatocyte function in sepsis: Kupffer cells mediate a biphasic protein synthesis response in hepatoeytes after exposure to endotoxin or killed E coli. Surgery. 1985;98:388-395.
28. West MA, Keller GA, Hyland BJ, Cerra FB, Simmons RL. Further characterization of Kupffer cell/macrophage-mediated alterations in hepatocyte protein synthesis. Surgery. 1986;100:416-424.
29. Darlington GJ, Wilson DR, Lachman LB. Monocyte-conditioned medium, interleukin 1, and tumor necrosis factor stimulate the acute-phase response in human hepatoma cells in vitro. J Cell Biol. 1986;103:787-793.
30. Baumann H, Jahreis GP, Saunder DN, Koj A. Human keratinocytes and monocytes release factors which regulate the synthesis of major acute phase plasma proteins in hepatic cells from man, rat and mouse. J Biol Chem. 1984;259:7331-7342.
31. Arita H, Ogle CK, Alexander JW, Warden GD. Induction of hypermetabolism in guinea pigs by endotoxin infused through the portal vein. Arch Surg. 1988;123:1420-1424.
32. Faist E, Mewes A, Baker CC, et al. Prostaglandin E2 (PGE2)-dependent suppression of interleukin 2 (IL-2) production in patients with major trauma. J Trauma. 1987;27:837-848.
33. Boraschi D, Censini S, Tagliabue A. Interferon reduces macrophage-suppressive activity by inhibiting prostaglandin E2 release and inducing interleukin 1 production. J Immunol. 1984;133:764-768.
34. Wichterman KA, Baue AE, Chaudry IH. Sepsis and septic shock: a review of laboratory models and a proposal. J Surg Res. 1980;29:189-201.