TGF-β induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop

Cell

Volumn 63, Issue 3, 1990, Pages 515-524

  Battegay, Edouard J ^a   Raines, Elaine W ^a   Seifert, Ronald A ^a   Bowen Pope, Daniel F ^a   Ross, Russell ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; CELL CULTURE; CELL GROWTH; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

AORTA, THORACIC; CARTILAGE; CELL DIVISION; CELLS, CULTURED; DNA REPLICATION; HUMAN; INFANT, NEWBORN; MACROMOLECULAR SYSTEMS; MUSCLE, SMOOTH, VASCULAR; PLATELET-DERIVED GROWTH FACTOR; RECEPTORS, CELL SURFACE; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA;

EID: 0025114866     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(90)90448-N     Document Type: Article

References (57)

1. An activated form of transforming growth factor β is produced by cocultures of endothelial cells and pericytes
2. Type β transforming growth factor in human platelets: release during platelet degranulation and action on vascular smooth muscle cells
3. Transforming growth factor-β in human platelets
4. cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines
5. Methods for studying the platelet-derived growth factor receptor
6. Transforming growth factor β is a bifunctional regulator of replication and collagen synthesis in osteoblast-enriched cell cultures from fetal bone
7. Transforming growth factor β specifically stimulates synthesis of proteoglycan in human adult arterial smooth muscle cells
8. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
9. Cultured human endothelial cells express platelet-derived growth factor B chain:cDNA cloning and structural analysis
10. Differential inhibition of transforming growth factor β1 and β2 activity by α2-macroglobulin
11. Transforming growth factor β responsiveness is modulated by extracellular collagen matrix during hepatic Ito cell culture
12. Regulation of protein synthesis in mitogenactivated bovine lymphocytes
13. Differential regulation of expression of two platelet-derived growth factor receptor subunits by transforming growth factor β
14. Synthesis, phosphorylation, and degradation of multiple forms of platelet-derived growth factor receptor studied using a monoclonal antlbody
15. Two classes of PDGF receptor recognize different isoforms of PDGF
16. Biochemical evidence for multiple classes of PDGF receptor
17. Purification of PDGF-AB and PDGF-BB from human platelet extracts and identification of all three PDGF dimers in human platelets
18. Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptors
19. Dimerization of B-type platelet-derived growth factor receptors occurs after ligand binding and is closely associated with receptor kinase activation
20. Bi-functional action of transforming growth factor-β on DNA synthesis in early passage human fetal fibroblasts
21. Transforming growth factor-β and the initiation of chondrogenesis and osteogenesis in the rat femur
22. High and low affinity binding of heparin-binding growth factor to a 130-kDa receptor correlates with stimulation and inhibition of growth of a differentiated human hepatoma cell
23. The B chain of PDGF alone is sufficient for mitogenesis
24. Transforming growth factor-β regulates growth as well as collagen and fibronectin synthesis of human marrow fibroblasts
25. Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor β: a proposed model for indirect mitogenesis involving autocrine activity
26. Regulation of extracellular matrix RNA levels in cultured smooth muscle cells
27. Interleukin 1: a mitogen for human vascular smooth muscle cells that induces the release of growth-inhibitory prostanoids
28. The antiproliferative effect of type beta transforming growth factor occurs at a level distal from receptors for growth-activating factors
29. Transforming growth factors and the regulation of cell proliferation
30. Beta-type transforming growth factor specifies organizational behavior in vascular smooth muscle cell cultures
31. Role of PDGF-A expression in the control of vascular smooth muscle cell growth by TGF-β
32. The TGF-β family of growth and differentiation factors
33. Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes
34. 2-macroglobulin inactive complex
35. Differential inhibitory effects of TGF-β on EGF-, PDGF-, and HBGF-1-stimulated MG63 human osteosarcoma cell growth: possible involvement of growth factor interactions at the receptor and postreceptor levels
36. Transforming growth factor-β1 binds to immobilized fibronectin
37. Inhibition of normal rat kidney cell growth by transforming growth factor-β is mediated by collagen
38. Density-dependent inhibition of cell growth by transforming growth factor-β1 in normal human fibroblasts
39. Transforming growth factor β1 suppression of c-myc gene transcription: role in inhibition of keratinocyte proliferation
40. Purification of human platelet-derived growth factor
41. Interleukin-1 mltogenic activity for fibroblasts and smooth muscle cells is due to PDGF-AA
42. Platelet-derived growth factor
43. The pathogenesis of atherosclerosis—an update
44. Localization of PDGF-B protein in macrophages in all phases of atherogenesis
45. Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming factor-β1-like molecule by plasmin during co-culture
46. Two different subunits associate to create isoform-specific platelet-derived growth factor receptors
47. Type β transforming growth factor/growth inhibitor stimulates entry of monolayer cultures of AKR-2B cells into S phase after a prolonged prereplicative interval
48. Radioimmunoassay of human platelet-derived growth factor using monoclonal antibody toward a synthetic 73–97 fragment of its B-chain
49. TGF-β stimulates primary human skin fibroblast DNA synthesis via an autocrine production of PDGF-related peptides
50. Transforming growth factor-β: biological function and chemical structure
51. Some recent advances in the chemistry and biology of transforming growth factor-beta
52. Transforming growth factor-β promotes the growth of mouse uterus and vagina in vivo
53. TGF-β inhibition of endothelial cell proliferation: alteration of EGF binding and EGF-induced growth-regulatory (competence) gene expression
54. Differential effects of transforming growth factor-β and epidermal growth factor on the cell cycle of cultured rabbit articular chondrocytes
55. Role of serum components in density-dependent inhibition of growth of cells in culture
56. Distribution and modulation of the cellular receptor for transforming growth factor-beta