Dihydropyrimidine Calcium Channel Blockers. 2.1 3-Substituted-4-aryl-l,4-dihydro-6-methyl-5-pyrimidinecarboxylic Acid Esters as Potent Mimics of Dihydropyridines

Journal of Medicinal Chemistry

Volumn 33, Issue 9, 1990, Pages 2629-2635

  Atwal, Karnail S ^a   Rovnyak, George C ^a   Kimball, S David ^a   Floyd, David M ^a   Moreland, Suzanne ^a   Swanson, Brian N ^a   Gougoutas, Jack Z ^a   Schwartz, Joseph ^a   Smillie, Kaye M ^a   Malley, Mary F ^a  

^a Squibb Inst for Medical Research   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIHYDRO 6 METHYL 4 PHENYL 2 THIOXO 3,5 PYRIMIDINEDICARBOXYLIC ACID DIETHYL ESTER; 1,4 DIHYDRO 6 METHYL 4 PHENYL 5 PYRIMIDINECARBOXYLIC ACID DERIVATIVE; CALCIUM CHANNEL; NITRENDIPINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; DRUG METABOLISM; DRUG SCREENING; DRUG SYNTHESIS; GUINEA PIG; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION; VASODILATATION;

ANIMAL; CALCIUM CHANNEL BLOCKERS; CHEMISTRY; DIHYDROPYRIDINES; MALE; MUSCLE, SMOOTH, VASCULAR; PYRIMIDINES; RABBITS; RATS; RATS, INBRED STRAINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0025105557     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00171a044     Document Type: Article

References (21)

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