Inhibition of histamine skin flare reaction following repeated topical applications of capsaicin

Allergy

Volumn 45, Issue 2, 1990, Pages 121-125

  Bjerring, P ^a   Arendt Nielsen L ^b  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b Department of Medical Informatics ^*  (Denmark)

Author keywords

flare; histamine; skin; topical capsaicin

Indexed keywords

CAPSAICIN; HISTAMINE;

ADULT; ARTICLE; HUMAN; HUMAN EXPERIMENT; NORMAL HUMAN; PRIORITY JOURNAL; SKIN INFLAMMATION; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; ADULT; CAPSAICIN; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; ERYTHEMA; HISTAMINE; HUMAN; MIDDLE AGE; NERVE FIBERS; SKIN; SUPPORT, NON-U.S. GOV'T;

EID: 0025105264     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/j.1398-9995.1990.tb00469.x     Document Type: Article

References (24)

1. Effects of capsaicin applied locally to adult peripheral nerve
2. Topical capsaicin pretreatment inhibits axon reflex vasodilatation caused by somatostatin and vasoactive intestinal polypeptide in human skin
3. The effects of locally applied capsaicin on conduction in cutaneous nerves in four mammalian species
4. Histamine is released from skin by substance P but does not act as the final vasodilator in the axon reflex
5. On the origin from the spinal cord of the vasodilator fibres of the hind limb, and on the nature of these fibres
6. Bradykinin, Substance P, Prostaglandin E2 and Papain induced flare suppressed by capsaicin
7. Inhibition of axon reflex vasodilatation by topically applied capsaicin
8. Treatment of chronic postherpetic neuralgia with topical capsaicin
9. The value of axon responses in determining the site of lesion in traction injuries of brachial plexus
10. Vascular and sensory responses of human skin to mild injury after topical treatment with capsaicin
11. Structure‐activity relationships for some substance P‐related peptides that cause wheal and flare reactions in human skin
12. Capsaicin applied to peripheral nerve inhibits axoplasmic transport of substance P and somatostatin
13. The inhibitory effect of antiallergy drugs on allergen and histamine induced wheal and flare response
14. Peptide biosynthesis in sensory ganglia
15. Increase in tissue concentration of histamine and 5‐ hydroxytryptamine following capsaicin treatment of newborn rats
16. Flare and itch induced by substance P in human skin
17. The action of local anesthetics on histamine release
18. The immediate and long‐term effects of applying capsaicin to cutaneous nerves
19. The presence of histamine in tissue mast cells
20. Functional and fine structural characteristics of the sensory neuron blocking effect of capsaicin
21. Capsaicin prevents histamine‐induced itching
22. The effect of capsaicin on some experimental inflammations in human skin
23. The effect of capsaicin application to a peripheral nerve on impulse conduction in functionally identified afferent nerve fibres