Cryoprotectant toxicity and cryoprotectant toxicity reduction: In search of molecular mechanisms

Cryobiology

Volumn 27, Issue 3, 1990, Pages 247-268

  Fahy, Gregory M ^a   Lilley, Terence H ^b   Linsdell, Helen ^b   Douglas, Mary St John ^a   Meryman, Harold T ^a  

^a HOLLAND LABORATORY   (United States)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CRYOPROTECTIVE AGENT; DIMETHYL SULFOXIDE; FRUCTOSE BISPHOSPHATASE; LYSINE; WATER;

ANIMAL CELL; CONFERENCE PAPER; CRYOPROTECTION; ENZYME INACTIVATION; GLYCOLYSIS; NONHUMAN;

AMIDES; ANIMAL; CRYOPROTECTIVE AGENTS; DIMETHYL SULFOXIDE; DRUG INTERACTIONS; HUMAN; PROTEIN DENATURATION; PROTEINS; SUPPORT, U.S. GOV'T, P.H.S.;

ANIMALIA;

EID: 0025102358     PISSN: 00112240     EISSN: 10902392     Source Type: Journal    
DOI: 10.1016/0011-2240(90)90025-Y     Document Type: Article

References (80)

1. Dimethyl sulfoxide as a spray reagent for the detection of triterpenoids and some steroids on thin-layer plates
2. Mechanisms of cell fusion
3. Mechanism of poly(ethylene glycol) interaction with proteins
4. Cryoprotection of human platelets with high concentrations of propylene glycol and glycerol
5. Biochemical effects on kidney of exposure to high concentrations of dimethyl sulphoxide
6. Aqueous solutions containing amino acids and peptides. Part 19. The enthalpic coefficients for the interactions of N-acetylsarcosinamide with 2-(N-acetylamino)acyl amides at 25 °C
7. Aqueous solutions containing amino acids and peptides. Part 13.—Enthalpy of dilution and osmotic coefficients of some N-acetyl amino acid amides and some N-acetyl peptide amides at 298.15 K
8. Solute–solute–solvent interactions in aqueous solutions of triethanolamine and dimethylsulfoxide. Microcalorimetric study
9. Transcription in vitro using mixtures of ethylene glycol and water
10. Effect of fructose, dihydroxyacetone, glycerol, and glucose on metabolites and related compounds in liver and kidney
11. The enthalpies of interaction of some amides with urea in water at 25 °C
12. Cytolysis of yeast cells, caused by dimethylsulfoxide. Antonie van Leeuwenhoek 35
13. Viability assays-A critique
14. The use of dimethyl sulfoxide(DMSO) for protein fractionation.
15. Denaturation of human and Glycera dibranchiata hemoglobins by the urea and amide classes of denaturants
16. Prevention of toxicity from high concentrations of cryoprotective agents
17. Viability concepts in organ preservation
18. Cryoprotectant toxicity neutralizers reduce freezing injury
19. Cryoprotectant toxicity: Biochemical or osmotic?
20. The relevance of cryoprotectant “toxicity” to cryobiology
21. Cryoprotectant toxicity reduction: Specific or non-specific?
22. Vitrificaton of multicellular systems and whole organs
23. Prospects for organ preservation by vitrification
24. Some emerging principles underlying the physical properties, biological actions, and utility of vitrification solutions
25. Vitrification as an approach to cryopreservation
26. Structural changes of ribosome by the action of ethylene glycol
27. Dimethylsulfoxide induces aneuploidy in a fungal test system
28. The stability of protein structure in aqueous propylene glycol, amino acid solubility and preferential solvation of protein
29. Effects of dimethylsulfoxide on metabolism of isolated perfused rat brain
30. Calorimetric study of association of diketopiperazine in water
31. Dimethyl sulfoxide can initiate cell divisions of arrested callus protoplasts by promoting cortical microtubule assembly
32. Structure of muramidase (lysozyme). VIII. Effect of dimethyl sulfoxide on the stability of muramidase
33. Solvent denaturation of globular proteins. Unfolding by the monalkyl-and dialkyl-substituted formamides and ureas
34. Solution studies of the nucleic acid bases and related model compounds. Solubility in aqueous urea and amide solutions
35. On the structural stability and solvent denaturation of proteins. I. Denaturation by the alcohols and glycols
36. Solution studies of the nucleic acid bases and related model compounds. Solubility in aqueous alcohol and glycol solutions
37. 7p
38. 13C-NMR study of glycerol metabolism in rabbit renal cells of proximal convoluted tubules
39. The effect of dimethylsulphoxide on the microtubular system of the mouse oocyte
40. Biological Effects of Acetamide, Formamide, and Their Monomethyl and Dimethyl Derivatives
41. Role of water structure in macromolecules
42. Cryoprotectants as kosmotropic hofmeister solutes
43. II) phase at the expense of lamellar liquid-crystalline phase in hydrated phosphatidylethanola-mines
44. The effect of dimethylsulphoxide on the permeability of the lysosomal membrane
45. Interactions between amino acids and peptides in water
46. Thermodynamics of peptides and model systems
47. Molecular basis of the biological compatibility of nature's osmolytes
48. Phospholipid membrane stabilization by dimethylsulfoxide and other inducers of Friend leukemic cell differentiation
49. Membrane action of DMSO and other chemical inducers of Friend leukaemic cell differentiation
50. Cryoprotectant-induced redistribution of intramembranous particles in mouse lymphocytes
51. The effect of DMSO on fructose-1,6-diphosphatase
52. +-adenozintrifosfatazy dimetilsulfoxsidom pri inaktivatsii mochevinoi
53. Hydrogen bonding between nucleic acid constituents and amino acid amide group
54. Matters arising
55. Activation of transcription at specific promoters by glycerol
56. Enhancement of F-actin/alpha-actinin association in the presence of 1,2-propanediol
57. Interaction between dimethyl sulfoxide and formamide in the liquid state
58. The optimization of a mixture of two permeating cryoprotectants
59. Membrane lipid phase separations at low temperature
60. Chemical inducers of differentiation cause conformational changes in the chromatin and deoxyribonucleic acid of murine erythroleukemia cells
61. Effects of organic solvents on the cytoskeleton of mammalian oocytes and embryos: implications for the cryopreservation of cells
62. Tubulin polymerization in dimethyl sulfoxide
63. 2′-dibutyryl cyclic adenosine monophosphate
64. Pressure-induced depolymerization of brain microtubules in vitro
65. Solvent denaturation
66. Thermal denaturation of chromatin and lysine copolymer-DNA complexes. Effects of ethylene glycol
67. Kinetics of glycerol uptake by the perfused rat liver: membrane transport, phosphorylation and effect on NAD redox level
68. The influence of thyroid state on glycerol-induced hyperpolarization of the cell membranes in isolated, perfused rat liver
69. Oxidation of sulfhydryl groups to disulfides by sulfoxides
70. From dogfish to dogs: Trimethylamines protect proteins from urea
71. Activation of low molecular weight acid phosphatase from bovine brain by purines and glycerol
72. Separation of plasma membrane markers by glycerol-induced blistering of muscle cells
73. Effect of 1,2-pro-panediol and dimethylsulphoxide on the meiotic spindle of the mouse oocyte
74. Experimental cryopreservation: A model for the freezing of human embryos and oocytes
75. Cryopreservation of ovulated rabbit oocytes: Cryoprotectant effect on microfilament and microtubule organization. In vivo survival after freezing
76. Comparative effect of cryoprotectants on rabbit embryos cytoskeleton
77. Neutral salts: The generality of their effects on the stability of macromolecular conformations
78. Single-strand breaks in DNA of various organs of mice induced by methyl methanesulfonate and dimethylsulfoxide determined by the alkaline unwinding technique
79. Denaturation of globular proteins. III. A comparative study of the interaction of urea with several proteins
80. Living with water stress: Evolution of osmolyte systems