Characterization of binding and biological effects of monoclonal antibodies against a human tumor necrosis factor receptor

Journal of Experimental Medicine

Volumn 171, Issue 2, 1990, Pages 415-426

  Espevik, Terje ^a   Brockhaus, Manfred ^b   Loetscher, Hansruedi ^b   Nonstad, Unni ^a   Shalaby, Refaat ^a  

^a NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

LYMPHOTOXIN; MEMBRANE RECEPTOR; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR;

ARTICLE; CELL CULTURE; CYTOCHEMISTRY; FLOW CYTOMETRY; HUMAN; PRIORITY JOURNAL;

ANTIBODIES, MONOCLONAL; BINDING, COMPETITIVE; CELL LINE; CELL SURVIVAL; EPITOPES; FLOW CYTOMETRY; HUMAN; LYMPHOTOXIN; RECEPTORS, CELL SURFACE; RECEPTORS, TUMOR NECROSIS FACTOR; RECOMBINANT PROTEINS; TUMOR NECROSIS FACTOR;

EID: 0025098536     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.171.2.415     Document Type: Article

References (21)

1. Kelker, H. C, J. D. Oppenheim, D. Stone-Wolf, D. Henriksen-DeStefano, B. Aggarwal, H. C. Stevenson, and J. Vilcek. 1985. Characterization of human tumor necrosis factor produced by peripheral blood monocytes and its separation from lymphotoxin. Int. J. Cancer. 36:69.
2. Cuturi, M. C, M. Murphy, M. P. Costa-Giomi, R. Weinmann, B. Perussia, and G. Trinchieri. 1987. Independent regulation of tumor necrosis factor and lymphotoxin production by human peripheral blood lymphocytes. J. Exp. Med. 165:1581.
3. Pennica, D., G. E. Nedwin, J. S. Hayflick, P. H. Seeburg, R. Derynck, M. A. Palladino, W. J. Kohr, B. B. Aggarwal, and D. V. Goeddel. 1984. Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin. Nature (Lond). 312:724.
4. Gray, P. W., B. B. Aggarwal, C. V. Benton, T. S. Bringman, W.J. Henzel, J. A. Jarret, D. W. Leung, B. Moffat, P. Ng, L. P. Svedersky, M. A. Palladino, and G. E. Nedwin. 1984. Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumor necrosis activity. Nature (Lond.). 312:721.
5. Sugarman, B. J., B. B. Aggarwal, P. E. Hass, I. Figari, M. A. Palladino, and H. M. Shephard. 1985. Recombinant human tumor necrosis factor-α: effects on proliferation of normal and transformed cells in vitro. Science (Wash. DC). 230:943.
6. Vilcek, J., V.J. Palombella, D. Henriksen-DeStefano, C. Swenson, R. Feinman, M. Hirai, and M. Tsujimoto. 1986. Fibroblast growth enhancing activity of tumor necrosis factor and its relationship to other polypeptide growth factors. J. Exp. Med. 163:632.
7. Nawroth, P. P., and J. Stern. 1986. Modulation of endothelial cell hemostatic properties by tumor necrosis factor. J. Exp. Med. 163:740.
8. Shalaby, M. R., B. B. Aggarwal, E. Rinderknecht, L. P. Svedersky, B. S. Finkle, and M. A. Palladino. 1985. Activation of human polymorphonuclear neutrophil functions by interferon-gamma and tumor necrosis factors. J. Immunol. 135:2069.
9. Ranges, G. E., I. S. Figari, T. Espevik, and M. A. Palladino. 1987. Inhibition of cytotoxic T cell development by transforming growth factor-β and reversal by recombinant tumor necrosis factor-α. J. Exp. Med. 166:991.
10. Kehrl, J. H., A. Miller, and A. Fauci. 1987. Effects of tumor necrosis factor α on mitogen-activated human B cells. J. Exp. Med. 166:786.
11. 1 and recombinant human tumor necrosis factor-α reciprocally regulate the generation of lymphokine-activated killer cell activity. J. Immunol. 140:2312.
12. Aggarwal, B. B., T. E. Eessalu, and P. E. Hass. 1985. Characterization of receptors for human tumour necrosis factor and their regulation by γ-interferon. Nature (Lond.). 318:665.
13. Creasy, A. A., R. Yamamoto, and C. R. Vitt. 1987. A high molecular weight component of the human tumor necrosis factor receptor is associated with cytotoxicity. Proc. Natl. Acad Sci. USA. 84:3293.
14. Hohmann, H. P., R. Remy, M. Brockhaus, and A. P. G. M. van Loon. 1989. Two different cell types have different major receptors for human tumor necrosis factor (TNF-α). J. Biol. Chem. 264:14972.
15. Kramer, S. M., and M. E. Craver. 1986. Serum-free in vitro bioassay for the detection of tumor necrosis factor. J. Immunol. Methods. 93:210.
16. Updyke, T. V., and G. L. Nicoloson. 1984. Immunoafnnity isolation of membrane antigens with biotinylated monoclonal antibodies and immobilized streptavidin matrices. J. Immunol. Methods. 73:83.
17. Wall, R. T., L. A. Harker, L.J. Quadrucci, and G. E. Striker. 1978. Factors influencing endothelial cell proliferation in vitro. J. Cell. Physiol. 96:203.
18. Shalaby, M. R., A. Waage, and T. Espevik. 1989. Cytokine regulation of interleukin-6 production by human endothelial cells. Cell. Immunol. 121:372.
19. Gamble, J. R., J. M. Harland, S.J. Klebanoff, A. F. Lopez, and M. A. Vadas. 1985. Stimulation of the adherence of neutrophils to umbilical vein endothelium by human recombinant tumor necrosis factor. Proc. Natl. Acad. Sci. USA. 882:8667.
20. Locksley, R. M., F. P. Heinzel, H. M. Shephard, J. Agosti, T. E. Eessalu, B. B. Aggarwal, and J. M. Harland. 1987. Tumor necrosis factors α and β differ in their capacities to generate interleukin 1 release from human endothelial cells. J. Immunol. 139:1891.
21. Yonehara, S., A. Ishii, and M. Yonehara. 1989. A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen codownregulated with the receptor of tumor necrosis factor. J. Exp. Med. 169:1747.