Pharmacokinetics and protein binding of methocarbamol in renal insufficiency and normals

European Journal of Clinical Pharmacology

Volumn 39, Issue 2, 1990, Pages 193-194

  Sica, D A ^a   Comstock, T J ^b   Davis, J ^a   Manning, L ^c   Powell, R ^c   Melikian, A ^c   Wright, G ^c  

^a Box 980160   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c PFIZER INC   (United States)

Author keywords

haemodialysis; methocarbamol; pharmacokinetics

Indexed keywords

METHOCARBAMOL;

ADULT; ARTICLE; CLINICAL ARTICLE; DRUG PROTEIN BINDING; FEMALE; HEMODIALYSIS; HUMAN; HUMAN EXPERIMENT; KIDNEY FAILURE; MALE; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PHARMACOKINETICS; PRIORITY JOURNAL;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COMPARATIVE STUDY; FEMALE; HUMAN; KIDNEY DISEASES; MALE; METHOCARBAMOL; PROTEIN BINDING; RENAL DIALYSIS;

EID: 0025075861     PISSN: 00316970     EISSN: 14321041     Source Type: Journal    
DOI: 10.1007/BF00280060     Document Type: Article

References (7)

1. Metabolism of methocarbamol in the rat, dog, and human
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3. Liver dysfunction in dialysis patients
4. Uremia and the liver. II. Drugs and the liver in the uremic patient
5. Glucuronidation and disposition of drug glucuronides in patients with renal failure
6. Method of estimating relative absorption of a drug in a series of clinical studies in which blood levels are measured after single and/or multiple doses