Cytogenetics and DNA amplification in colorectal cancers

Genes, Chromosomes and Cancer

Volumn 2, Issue 1, 1990, Pages 63-70

  Brüderlein, Silke ^a   Van Der Bosch, Kai ^a   Schlag, Peter ^b   Schwab, Manfred ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL CULTURE; CLINICAL ARTICLE; COLORECTAL CANCER; CYTOGENETICS; CYTOLOGY; FEMALE; GENE AMPLIFICATION; HEREDITY; HUMAN; HUMAN CELL; MALE;

ANIMAL; CHROMOSOME ABERRATIONS; COLORECTAL NEOPLASMS; GENE AMPLIFICATION; GENES, MYC; HUMAN; LIVER NEOPLASMS; LUNG NEOPLASMS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; ONCOGENES; PROTO-ONCOGENE PROTEINS; RECEPTOR, ERBB-2; SUPPORT, NON-U.S. GOV'T; TUMOR CELLS, CULTURED;

EID: 0025040604     PISSN: 10452257     EISSN: 10982264     Source Type: Journal    
DOI: 10.1002/gcc.2870020112     Document Type: Article

References (32)

1. Oncogene amplification in tumor cells
2. Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c‐myc) in malignant neuroendocrine cells from a human colon carcinoma
3. Aberrant expression of an amplified c‐myb oncogene in two cell lines from a colon carcinoma
4. Amplified NMYC in human neuroblastomas is often arranged as clustered tandem repeats of differently recombined DNA
5. Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas
6. Prevalence of ras gene mutations in human colorectal cancers
7. Expression of the c‐erbB‐2 gene product (p185) at different stages of neoplastic progression in the colon
8. Nuclear oncogene amplification or rearrangement is not involved in human colorectal malignancies
9. Identification of a chromosome 18q gene that is altered in colorectal cancers
10. Detection of high incidence of K‐ras oncogenes during human colon tumorigenesis
11. Double minutes and Cbandless chromosomes in a mouse tumor
12. Tumorigenicity of SEWA murine cells correlates with degree of c‐myc amplification
13. Chromosome 1 deletion in human neuroblastomas: Generation and fine mapping of microclones from the distal 1p region
14. Mutations in the p53 gene occur in diverse human tumor types
15. Loss of constitutional heterozygosity in colon carcinoma from patients with familial polyposis coli
16. Characteristics of cell lines established from human colorectal carcinoma
17. Double minutes in human large bowel cancer
18. Chromosomal banding patterns in human large bowel cancer
19. Karyotypic findings in a colonic villous adenoma
20. Amplification of NMYC in human neuroblastomas
21. Amplification of cellular oncogenes: A predictor of clinical outcome in human cancer
22. A cellular oncogene (c‐Ki‐ras) is amplified, overexpressed and located within karyotypic abnormalities in mouse adrenocortical tumor cells
23. Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumor
24. Amplification and enhanced expression of the c‐myc oncogene in mouse SEWA tumour cells
25. Oncogene amplification in colorectal cancer
26. Studies of the HER‐2/neu proto‐oncogene in human breast and ovarian cancer
27. Chromosome 5 allele loss in human colorectal carcinomas
28. Sporadic amplification of the HER2lneu protooncogene in adenocarcinomas of various tissues
29. The chromosomal analysis of human solid tumors
30. Genetic alterations during coloreetal‐tumor development
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32. Neuroblastoma consensus deletion maps to chromosome band 1p36.1.2