Inhibition of Enzymes of Estrogen and Androgen Biosynthesis by Esters of 4-Pyridylacetic Acid

Journal of Medicinal Chemistry

Volumn 33, Issue 11, 1990, Pages 3050-3055

  McCague, Raymond ^a   Rowlands, Martin G ^a   Barrie, S Elaine ^a   Houghton, John ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

(4 PYRIDYL)ACETIC ACID DERIVATIVE; AMINOGLUTETHIMIDE; AROMATASE; KETOCONAZOLE; STEROID 17,20 LYASE; STEROID 17ALPHA MONOOXYGENASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; RAT; SWINE;

ACETIC ACIDS; ALDEHYDE-LYASES; ANDROGENS; ANIMAL; AROMATASE; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; CYTOCHROME P-450 ENZYME SYSTEM; ESTERS; ESTROGENS; FEMALE; HUMAN; MALE; MOLECULAR STRUCTURE; PLACENTA; PYRIDINES; RATS; STEROID 17-ALPHA-HYDROXYLASE; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T; TESTIS;

EID: 0025039347     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00173a022     Document Type: Article

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