Structure and function of the (A) BC excinuclease of Escherichia coli

Mutation Research-DNA Repair

Volumn 236, Issue 2-3, 1990, Pages 203-211

  Selby, Christopher P ^a   Sancar, Aziz ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

DNA, damaged; Excinuclease, (A)BC; Proteins, UvrAS, UvrB and UvrC

Indexed keywords

4 NITROQUINOLINE 1 OXIDE; CISPLATIN; MITOMYCIN; PSORALEN;

DNA DAMAGE; ENZYME MECHANISM; ENZYME STRUCTURE; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; REVIEW;

DNA REPAIR; ENDODEOXYRIBONUCLEASES; ESCHERICHIA COLI; MODELS, BIOLOGICAL; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0025033354     PISSN: 09218777     EISSN: None     Source Type: Journal    
DOI: 10.1016/0921-8777(90)90005-P     Document Type: Article

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4. Promoter properties and negative regulation of the uvrA gene by the LexA repressor and its amino-terminal DNA binding domain
5. Release of ultraviolet light-induced thymine dimers from DNA in E. coli K-12
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7. Involvement of helicase II (uvrD gene product) and DNA polymerase I in excision mediated by the uvrABC protein complex
8. Incision of damaged versus nondamaged DNA by the Escherichia coli UvrABC proteins
9. Use of psoralen-modified oligonucleotides to trap three-stranded RecA-DNA complexes and repair of these cross-linked complexes by ABC excinuclease
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13. Effect of a lexA41(Ts) mutation on DNA repair and recA(Def) derivatives of Escherichia coli K-12
14. DNA and RNA sequence determination based on phosphorothioate Chemistry
15. Structure and expression of the gene locus encoding the phosphatidylylycerophosphate synthase of Escherichia coli
16. In vitro study of the interaction of the LexA repressor and the UvrC protein with a uvrC regulatory region
17. Three loci in Escherichia coli K-12 that control the excision of pyrimidine dimers and certain other mutagen products in DNA
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19. Sequences of the uvrA gene and protein reveal two potential ATP binding sites
20. Thymine dimers bend DNA
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26. Analysis of mRNA synthesis following induction of the Escherichia coli SOS system
27. Regulation of the Escherichia coli excision repair gene uvrC overlap between the uvrC structural gene and the region coding for a 24 kD protein
28. Utilization of DNA photolyase, pyrimidine dimer endonucleases, and alkaline hydrolysis in the analysis of aberrant ABC excinuclease incision adjacent to UV-induced DNA photo products
29. Evidence from extended X-ray absorption fine structure and site-specific mutagenesis for zinc fingers in UvrA protein of Escherichia coli
30. The narX and narL genes encoding the nitrate-sensing regulators of Escherichia coli are homologous to a family of prokaryotic two-component regulatory genes
31. The (A)BC excinuclease of Escherichia coli has only the UvrB and UvrC subunits in the incision complex
32. DNA repair enzymes
33. A novel repair enzyme: UvrABC excision nuclease of Escherichia coli cuts a DNA strand on both sides of the damaged region
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35. Identification of the uvrB gene product
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37. lexA protein inhibits transcription of the E. coli uvrA gene in vitro
38. Escherichia coli DNA photolyase stimulates UvrABC excision nuclease in vitro
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41. Sequences of the Escherichia coli uvrC gene protein
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45. ABC excinuclease incises both 5′ and 3′ to the CC-1065-DNA adduct and its incision activity is stimulated by DNA helicase II and DNA polymerase I
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52. Repair of N-methyl-N′-nitro-N-nitrosoguanidine-induced DNA damage by ABC excinuclease
53. Action mechanism of ABC excision nuclease on a DNA substrate containing a psoralen crosslink at a defined position
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56. Analysis of sequential steps of nucleotide excision repair in Escherichia coli using synthetic substrates containing single psoralen adducts
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58. 6-methylguanine by ABC excinuclease of Escherichia coli in vitro
59. Role of ATP in excision repair of ultraviolet radiation damage in Escherichia coli
60. The purification of the Escherichia coli UvrABC incision system