Identification and isolation of a membrane protein necessary for leukotriene production

Nature

Volumn 343, Issue 6255, 1990, Pages 278-281

  Miller, Douglas K ^a   Gillard, John W ^b   Vickers, Philip J ^b   Sadowski, Sharon ^a   Léveillé, Claire ^b,c   Mancini, Joseph A ^b   Charleson, Peter ^b   Dixon, Richard A F ^a   Ford Hutchinson, Anthony W ^b   Fortin, Réjean ^b   Gauthier, Jacques Yves ^b   Rodkey, John ^a   Rosen, Ronda ^a   Rouzer, Carol ^b,d   Sigal, Irving S ^a   Strader, Catherine D ^a   Evans, Jilly F ^b  

^a MERCK RESEARCH LABORATORIES   (United States)

^b MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

^c UNIVERSITÉ LAVAL   (Canada)

^d WESTERN MARYLAND COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 [1 (4 CHLOROBENZYL) 5 METHOXY 2 METHYL 3 INDOLYL]PROPIONIC ACID; 3 [1 (4 HYDROXY 3 IODOBENZYL) 5 ISOPROPYL 3 (4 TRIAZENOPHENYLSULFONYL) 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; 3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; ARACHIDONATE 5 LIPOXYGENASE; CELL MEMBRANE PROTEIN; LEUKOTRIENE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; DRUG MECHANISM; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LEUKOCYTE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT;

AFFINITY LABELS; AMINO ACID SEQUENCE; ANIMAL; AZIDES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMAN; INDOLES; INFLAMMATION; KINETICS; LEUKOTRIENE ANTAGONISTS; LEUKOTRIENES; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; NEUTROPHILS; RATS;

ANIMALIA; SIGANUS;

EID: 0025021789     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/343278a0     Document Type: Article

References (16)

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