Potential Antitumor Agents. 59. Structure-Activity Relationships for 2-Phenylbenzimidazole-4-carboxamides, a New Class of “Minimal” DNA-Intercalating Agents Which May Not Act via Topoisomerase II

Journal of Medicinal Chemistry

Volumn 33, Issue 2, 1990, Pages 814-819

  Denny, William A ^a   Rewcastle, Gordon W ^a   Baguley, Bruce C ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

2 PHENYL 4 BENZIMIDAZOLECARBOXAMIDE; 2 PHENYL 4 BENZIMIDAZOLECARBOXAMIDE DERIVATIVE; AMSACRINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL CULTURE; CROSS RESISTANCE; CYTOTOXICITY; DNA BINDING; DRUG SCREENING; DRUG SYNTHESIS; INTRAPERITONEAL DRUG ADMINISTRATION; LEUKEMIA; LEUKEMIA P 388; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL;

ANIMAL; ANTINEOPLASTIC AGENTS; BENZIMIDAZOLES; CELL SURVIVAL; CHEMISTRY, PHYSICAL; DNA; DNA TOPOISOMERASES, TYPE II; INTERCALATING AGENTS; LEUKEMIA P388; MICE; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T; TUMOR CELLS, CULTURED;

EID: 0025020286     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00164a054     Document Type: Article

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