Short-chain fatty acids produced by anaerobic bacteria inhibit phagocytosis by human lung phagocytes

Journal of Infectious Diseases

Volumn 161, Issue 1, 1990, Pages 138-142

  Eftimiadi, Costantino ^a,b   Tonetti, M ^a,b   Cavallero, A ^a,b   Sacco, O ^a,b   Rossi, G A ^a,b  

^a UNIVERSITY OF GENOA   (Italy)

^b HARVARD SCHOOL OF DENTAL MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SHORT CHAIN FATTY ACID;

ANAEROBIC BACTERIUM; ARTICLE; CELL CULTURE; HUMAN; MACROPHAGE; NEUTROPHIL; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

CALORIMETRY; FATTY ACIDS; FATTY ACIDS, VOLATILE; HUMAN; HYDROGEN-ION CONCENTRATION; IN VITRO; LUNG; MACROPHAGES; NEUTROPHILS; PHAGOCYTES; PHAGOCYTOSIS; STAPHYLOCOCCUS AUREUS;

EID: 0025017773     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/161.1.138     Document Type: Article

References (15)

1. Bartlett J.B. Anaerobic pneumonias. Semin Infect Dis 1983;5:131–146
2. Toews G.B. Determinants of bacterial clearance from the lower respiratory tract. Semin Respir Infect 1986;1:68–78
3. Ingham H.R., Sisson P.R., Tharagonnet D, Selkon J.B., Codd A.A. Inhibition of phagocytosis in vitro by obligate anaerobes. Lancet 1977;2: 1252–1254
4. Botta G.A., Eftimiadi C, Costa A, Tonetti M, van Steenbergen T.J.M., de Graaff J. Influence of volatile fatty acids on human granulocyte chemotaxis. FEMS Microbiol Lett 1985;27:69–72
5. Eftimiadi C, Buzzi E, Tonetti M, Buffa P, Bufla D, van Steenbergen T.J.M., de Graaff J, Botta G.A. Short chain fatty acids produced by anaerobic bacteria alter the physiological responses of human neutrophils to chemotactic peptide. J Infect 1987;14:43–53
6. Rotstein O.D., Pruett T.L., Fiegel V.D., Nelson R.D., Simmons R.L. Succinic acid: a metabolic by-product of Bacteroides species inhibits polymorphonuclear leukocyte function. Infect Immun 1985;48:402–408
7. Rotstein O.D., Vittorini T, Kao J, McBurney M.I., Nasmith P.E., Grinstein S. A soluble Bacteroides by-product impairs phagocytic killing of Escherichia coli by neutrophils. Infect Immun 1989;57:745–753
8. Rossi G.A., Sacco O, Cosulich E, Risso A, Balbi B, Ravazzoni C. Helper T-lymphocytes in pulmonary sarcoidosis. Functional analysis of a lung T-cell subpopulation in patients with active disease. Am Rev Respir Dis 1986;133:1086–1090
9. Eftimiadi C, Rialdi G. Increased energy expenditure by granulocytes during phagocytosis of Staphylococcus aureus compared with other staphylococci. J Infect Dis 1984;150:366–371
10. Eftimiadi C, Rialdi G. Increased heat production proportional to oxygen consumption in human neutrophils activated with phorbol-12- myristate-13-acetate. Cell Biophys 1982;4:231–244
11. Hermans J Jr, Rialdi G. Heat of ionization and denaturation of sperm-whale myoglobin determined with a microcalorimeter. Biochemistry 1965;4:1277–1281
12. Reynolds H.Y., Newball H.H. Analysis of proteins and respiratory cells obtained from human lungs by bronchial lavage. J Lab Clin Med 1974;84:559–573
13. Gorbach S.L., Mayhew J.W., Bartlett J.G., Thadepalli H, Onderdonk A.B. Rapid diagnosis of anaerobic infections by direct gas-liquid chromatography of clinical specimens. J Clin Invest 1976;57:478–484
14. Hunter J.V., Chadwick M, Hutchinson G, Hodson M.E. Use of gas liquid chromatography in the clinical diagnosis of anaerobic pleuropulmonary infection. Br J Dis Chest 1985;79:1–8
15. Hoidal J.R., Schmeling D, Peterson P.K. Phagocytosis, bacterial killing, and metabolism by purified lung phagocytes. J Infect Dis 1981;144:61–71